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EJNMMI Research, ISSN 2191-219X, 12/2013, Volume 3, Issue 1, pp. 1 - 9
Expression of αvβ3 integrin is increased after myocardial infarction as part of the repair process. Increased expression of αvβ3 has been shown by molecular... 
Myocardial infarction | 68 Ga-NODAGA-RGD | Medicine & Public Health | Orthopedics | 18 F-galacto-RGD | Oncology | 68 Ga-TRAP(RGD) 3 | Nuclear Medicine | Imaging / Radiology | Cardiology | PET | F-galacto-RGD | Ga-NODAGA-RGD | Ga-TRAP(RGD)
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 03/2018, Volume 8, Issue 2, pp. 165 - 177
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential biomedical applications. With tailored mesoporous structure, huge... 
Mesoporous silica nanoparticles | Gene delivery | Poorly soluble drug | Cancer therapy | Multidrug resistance | CANCER-CELLS | OVERCOMING MULTIDRUG-RESISTANCE | PORE-SIZE | PHOTODYNAMIC THERAPY | CELLULAR UPTAKE | IN-VITRO | CO-DELIVERY | FACILE SYNTHESIS | ORAL BIOAVAILABILITY | PHARMACOLOGY & PHARMACY | TARGETED DELIVERY | GI, gastrointestinal | P-gp, P-glycoprotein | C dots, Cornell dots | GNRs@mSiO2, mesoporous silica-encapsulated gold nanorods | MSNs-TAT, TAT peptide-modified MSNs | PAMAM, polyamidoamine | Review | APTMS, amino propyl trimethoxysilane | TAT peptide-modified MSNs | MSNs-RGD | pDNA, plasmid DNA | PLL, poly-l-lysine | APTES, 3-aminopropyltriethoxysilane | BCS, Biopharmaceutical Classification System | LHRH, luteinising-hormone releasing hormone | EPR, enhanced permeability and retention | AO, acridine orange | MSNs, mesoporous silica nanoparticles | RGD, arginine-glycine-aspartate | PEG400, polyethylene glycol 400 | MDR, multi-drug resistance | MRP1, multidrug resistance protein 1 | NIR, near-infrared | PDEAEMA, poly (2-(diethylamino)ethylmethacrylate) | PTX, paclitaxel | FDA, Food and Drug Administration | Q-MSNs, quercetin encapsulated MSNs | MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide | MSNs@PDA-PEG-FA, poly(ethylene glycol)-folic acid-functionalized polydopamine-modified MSNs | CTAB, cetyltrimethyl ammonium bromide | PEI, polyethyleneimine | TMB, 1,3,5-trimethybenzene | BCL-2, B-cell lymphoma-2 | CMC, critical micelle concentration | MSNs-HA, hyaluronic acid-conjugated MSNs | TAT, trans-activating transcriptor | Bio-TEM, biological transmission electron microscopy | CPT, camptothecin | TAT, RGD | PDMAEMA, poly(2-(dimethylamino)ethylmethacrylate) | MSN-Dox-G2, Dox-loaded and G2 PAMAM-modified MSNs
Journal Article
European journal of nuclear medicine and molecular imaging, ISSN 1619-7089, 2016, Volume 43, Issue 11, pp. 2005 - 2013
This study was designed to determine safety, tolerability, and radiation burden of a [68Ga]NODAGA-RGD-PET for imaging integrin αvβ3 expression in patients with... 
[ 68 Ga]NODAGA-RGD | Metabolic stability | Whole-body distribution | Medicine & Public Health | Orthopedics | Oncology | Hepatocellular carcinoma | Nuclear Medicine | Dosimetry | Imaging / Radiology | Cardiology | PET | Ga]NODAGA-RGD | F-18-GALACTO-RGD | POSITRON-EMISSION-TOMOGRAPHY | CANCER-PATIENTS | INTEGRIN | [Ga-68]NODAGA-RGD | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Whole-Body Counting | Humans | Middle Aged | Male | Metabolic Clearance Rate | Integrin alphaVbeta3 - metabolism | Carcinoma, Hepatocellular - diagnostic imaging | Tissue Distribution | Coordination Complexes - pharmacokinetics | Radiation Exposure - analysis | Liver Cirrhosis - diagnostic imaging | Sensitivity and Specificity | Liver Cirrhosis - metabolism | Female | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Molecular Imaging - methods | Positron-Emission Tomography - methods | Radiation Dosage | Organ Specificity | Liver Neoplasms - diagnostic imaging | Peptides, Cyclic - pharmacokinetics | Liver Neoplasms - metabolism | Aged | Carcinoma, Hepatocellular - metabolism | Pets | Metabolites | Tracers (Biology) | Radiation | Hepatoma | Liver cirrhosis | Integrins | Dosimeters | Renal function | Radiochemical analysis | Liver | Radioisotopes | Bladder | Blood | Liver cancer | Computed tomography | Urinary bladder | Intestine | Tomography | Lesions | Background radiation | Radioactivity | Urine | Excretion | Stability | Medical imaging | Invasiveness | Organs | Positron emission | Muscles | Liquid chromatography | Injection | Metabolism | High-performance liquid chromatography | Patients | Radiation dosage | Cirrhosis | Lungs | Tumors | Pharmaceuticals | [68Ga]NODAGA-RGD | Original
Journal Article
Neuro-oncology (Charlottesville, Va.), ISSN 1523-5866, 2009, Volume 11, Issue 6, pp. 861 - 870
Inhibitors targeting the integrin α v β 3 are promising new agents currently tested in clinical trials for supplemental therapy of glioblastoma multiforme... 
Malignant glioma | F]Galacto-RGD | PET | Integrins | [18F]Galacto-RGD | αvβ3 | Clinical Investigations | integrins | malignant glioma
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 08/2014, Volume 11, Issue 8, pp. 2954 - 2961
The overexpression of integrin αvβ3 has been linked to tumor aggressiveness and metastasis in several cancer types. Because of its high affinity, peptides... 
RGD dimer | arginine-glycine-aspartic acid (RGD) peptides | molecular imaging | positron emission tomography (PET) | tumor angiogenesis | integrin αvβ3 | arginine−glycine−aspartic acid (RGD) peptides | scandium-44 (44Sc)
Journal Article
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 08/2011, Volume 52, Issue 8, pp. 1276 - 1284
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2007, Volume 13, Issue 22, pp. 6610 - 6616
Purpose: [ 18 F]Galacto-RGD has been developed for positron emission tomography (PET)–imaging of αvβ3 expression, a receptor involved in angiogenesis and... 
αvβ3 | image fusion | angiogenesis | RGD | kinetic modeling
Journal Article
Molecular Imaging and Biology, ISSN 1536-1632, 2/2012, Volume 14, Issue 1, pp. 88 - 95
A reliable and routine process to introduce a new 18F-labeled dimeric RGD-peptide tracer ([18F]FPP(RGD)2) for noninvasive imaging of αvβ3 expression in tumors... 
Medicine & Public Health | Peptides | [ 18 F]FPP(RGD) 2 | Automated radiosynthesis | Tumor angiogenesis | Oncology | Imaging / Radiology | Radiopharmaceuticals | Clinical PET | Integrins | F]FPP(RGD) | [18F]FPP(RGD)2
Journal Article
Synlett, ISSN 0936-5214, 2012, Volume 23, Issue 20, pp. 2899 - 2902
Abstract The Arg-Gly-Asp (RGD) tripeptide is the smallest recognition sequence for the α v β 3 integrin receptor. A number of nonpeptide analogues of the RGD... 
letter | integrins | peptidomimetics | trifluoroethylamine | RGD
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 08/2016, Volume 11, pp. 4247 - 4259
Journal Article
Journal Article