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Journal of Clinical Oncology, ISSN 0732-183X, 05/2010, Volume 28, Issue 13, pp. 2151 - 2158
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 2, pp. 635 - 642
Purpose To report the clinical outcome and late side effect profile of proton radiotherapy in the treatment of children with parameningeal rhabdomyosarcoma... 
Radiology | Hematology, Oncology and Palliative Medicine | Conformal radiotherapy | Late effects | Proton radiotherapy | Parameningeal rhabdomyosarcoma | Pediatric | NECK RHABDOMYOSARCOMA | HEAD | INTERGROUP RHABDOMYOSARCOMA | INTERNATIONAL-SOCIETY | INTENSITY-MODULATED RADIOTHERAPY | NONMETASTATIC RHABDOMYOSARCOMA | SOFT-TISSUE | CHILDREN | CHILDHOOD-CANCER | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PEDIATRIC-ONCOLOGY | Follow-Up Studies | Protons - adverse effects | Humans | Child, Preschool | Protons - therapeutic use | Infant | Male | Radiotherapy - adverse effects | Organ Sparing Treatments - methods | Rhabdomyosarcoma - radiotherapy | Meningeal Neoplasms - drug therapy | Rhabdomyosarcoma, Alveolar - mortality | Massachusetts | Female | Rhabdomyosarcoma - drug therapy | Child | Rhabdomyosarcoma - mortality | Rhabdomyosarcoma, Alveolar - drug therapy | Rhabdomyosarcoma, Alveolar - radiotherapy | Treatment Outcome | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Meningeal Neoplasms - mortality | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Meningeal Neoplasms - radiotherapy | Rhabdomyosarcoma, Embryonal - radiotherapy | Radiotherapy | Medical colleges | Nuclear radiation | Index Medicus | DIAGNOSIS | PATIENTS | NEOPLASMS | FAILURES | PHOTONS | TEETH | RADIATION DOSES | CARIES | HISTOLOGY | PROTONS | SINUSES | MEDICAL RECORDS | NOSE | RADIATION DOSE UNITS | RADIOLOGY AND NUCLEAR MEDICINE | PEDIATRICS | RADIOTHERAPY | SIDE EFFECTS | COBALT | CONTROL
Journal Article
International Journal of Radiation Oncology Biology Physics, ISSN 0360-3016, 04/2012, Volume 82, Issue 5, pp. 1764 - 1770
Purpose: To compare the dosimetric parameters of intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT) in patients with... 
Intensity-modulated radiotherapy | 3D-CRT | IMRT | Three-dimensional conformal radiotherapy | Rhabdomyosarcoma | Intermediate risk | TISSUE | CANCER | RADIATION-THERAPY | TRIAL | ONCOLOGY | NECK-RHABDOMYOSARCOMA | CARCINOMA | SURVIVORS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Organs at Risk - radiation effects | Humans | Rhabdomyosarcoma - pathology | Male | Radiotherapy, Intensity-Modulated - adverse effects | Rhabdomyosarcoma - radiotherapy | Rhabdomyosarcoma, Alveolar - mortality | Treatment Failure | Sarcoma - mortality | Female | Rhabdomyosarcoma - drug therapy | Rhabdomyosarcoma, Alveolar - pathology | Child | Rhabdomyosarcoma - mortality | Sarcoma - radiotherapy | Rhabdomyosarcoma, Embryonal - pathology | Radiotherapy, Intensity-Modulated - mortality | Rhabdomyosarcoma, Alveolar - drug therapy | Radiotherapy, Intensity-Modulated - methods | Rhabdomyosarcoma, Alveolar - radiotherapy | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Sarcoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Epidemiologic Methods | Radiotherapy, Conformal - mortality | Radiotherapy, Conformal - adverse effects | Rhabdomyosarcoma, Embryonal - radiotherapy | Radiotherapy, Conformal - methods | Nuclear radiation | Analysis | Radiation | Medical care | Universities and colleges | Radiotherapy | Methods | Quality management | Index Medicus | PATIENTS | NEOPLASMS | INTEGRAL DOSES | FAILURES | TOXICITY | COMPARATIVE EVALUATIONS | CHILDREN | PLANNING | MULTIVARIATE ANALYSIS | RADIOLOGY AND NUCLEAR MEDICINE | REGRESSION ANALYSIS | RADIOTHERAPY | CONTROL | HAZARDS
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2015, Volume 14, Issue 9, pp. 1389 - 1402
Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic... 
differentiation therapy | metabolism and cancer | miR-206 | Rhabdomyosarcoma | Differentiation therapy | MiR-206 | Metabolism and cancer | HMT, Histone MethylTransferase | PPP, Pentose Phosphate Pathway | MYOBLAST DIFFERENTIATION | MREs, MicroRNA Responsive Elements | DHEA, Dehydroepiandrosterone | DCA, Dichloroacetate | MRFs, Myogenic Regulatory Factors | DICHLOROACETATE DCA | CYCLIN D1 | G6PD, Glucose 6 Phosphate Dehydrogenase | myomiRs, muscle-specific microRNAs | MIR-206 | PDK, Pyruvate Dehydrogenase Kinase | CELL BIOLOGY | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE | TARGET GENES | RMS, Rhabdomyosarcoma | ALVEOLAR RHABDOMYOSARCOMA | SKELETAL | TCA cycle, TriCarboxylic Acid cycle | PDH, Pyruvate Dehydrogenase | EXPRESSION | SMYD1, SET and MYND domain-containing protein 1 | HISTONE METHYLTRANSFERASE | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | DNA-Binding Proteins - metabolism | Rhabdomyosarcoma, Embryonal - genetics | Transfection | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Muscle Proteins - metabolism | Rhabdomyosarcoma, Alveolar - pathology | Transcription, Genetic | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - drug therapy | Rhabdomyosarcoma, Alveolar - genetics | Rhabdomyosarcoma, Embryonal - enzymology | Signal Transduction | Rhabdomyosarcoma, Embryonal - drug therapy | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Myoblasts - pathology | Cell Transformation, Neoplastic - metabolism | Muscle Proteins - genetics | Transcription Factors - metabolism | Phenotype | Muscle Development - drug effects | Energy Metabolism | Rhabdomyosarcoma, Alveolar - enzymology | Cell Differentiation - drug effects | Dichloroacetic Acid - pharmacology | Muscle Fibers, Skeletal - pathology | Cell Line, Tumor | Glucosephosphate Dehydrogenase - metabolism | MicroRNAs - genetics | Glucosephosphate Dehydrogenase - genetics | Cell Transformation, Neoplastic - pathology | Myoblasts - enzymology | Muscle Fibers, Skeletal - enzymology | Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 86, Issue 1, pp. 58 - 63
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 96, Issue 5, pp. 1070 - 1077
Journal Article
Journal Article
Modern Pathology, ISSN 0893-3952, 06/2013, Volume 26, Issue 6, pp. 772 - 781
Rhabdomyosarcoma is a rare soft tissue sarcoma that typically affects children, adolescents, and young adults. Despite treatment via a multidisciplinary... 
Immunohistochemistry | Anaplastic lymphoma kinase | Fluorescence in situ hybridization | Rhabdomyosarcoma | ALK | PROTEIN | anaplastic lymphoma kinase | FUSION GENE | PATHOLOGY | IDENTIFICATION | CHILDRENS ONCOLOGY GROUP | fluorescence in situ hybridization | CELL LUNG-CANCER | INFLAMMATORY MYOFIBROBLASTIC TUMOR | ALVEOLAR RHABDOMYOSARCOMA | ONCOGENIC MUTATIONS | immunohistochemistry | rhabdomyosarcoma | EXPRESSION | Prognosis | Humans | Middle Aged | Child, Preschool | Male | Rhabdomyosarcoma, Embryonal - genetics | Young Adult | Rhabdomyosarcoma, Alveolar - therapy | DNA Mutational Analysis | Rhabdomyosarcoma, Alveolar - mortality | Rhabdomyosarcoma, Embryonal - therapy | Polymerase Chain Reaction | Adult | Female | Receptor Protein-Tyrosine Kinases - analysis | Rhabdomyosarcoma, Alveolar - pathology | Child | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - genetics | Rhabdomyosarcoma, Embryonal - enzymology | Biomarkers, Tumor - analysis | Kaplan-Meier Estimate | In Situ Hybridization, Fluorescence | Gene Dosage | Rhabdomyosarcoma, Embryonal - mortality | Forkhead Transcription Factors - genetics | Gene Amplification | Receptor Protein-Tyrosine Kinases - genetics | Rhabdomyosarcoma, Alveolar - enzymology | Gene Rearrangement | Adolescent | Biomarkers, Tumor - genetics | Forkhead Box Protein O1 | Mutation | Index Medicus
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2013, Volume 49, Issue 16, pp. 3462 - 3470
Abstract Background Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and adolescents. Since survival of high-risk patients... 
Hematology, Oncology and Palliative Medicine | Anaplastic lymphoma kinase receptor | Insulin-like growth factor 1 receptor | Embryonal rhabdomyosarcoma | Targeted treatment | In vitro | Alveolar rhabdomyosarcoma | METASTATIC RHABDOMYOSARCOMA | MONOCLONAL-ANTIBODY | MECHANISMS | COMBINATION | ONCOLOGY | RESISTANCE | INTERGROUP | OUTCOMES | INHIBITOR | IGF-1 RECEPTOR | EXPRESSION | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Middle Aged | Child, Preschool | Infant | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Young Adult | Netherlands | Rhabdomyosarcoma, Alveolar - mortality | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Rhabdomyosarcoma, Alveolar - pathology | Child | Infant, Newborn | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - drug therapy | Cell Survival - drug effects | Rhabdomyosarcoma, Embryonal - enzymology | Kaplan-Meier Estimate | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Chi-Square Distribution | Receptor Protein-Tyrosine Kinases - metabolism | Drug Synergism | Rhabdomyosarcoma, Alveolar - enzymology | Adolescent | Cell Line, Tumor | Aged | Protein Kinase Inhibitors - pharmacology | Lymphomas | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 385, pp. 251 - 260
Abstract Rhabdomyosarcomas (RMS) in children and adolescents are heterogeneous sarcomas broadly defined by skeletal muscle features and the presence/absence of... 
Hematology, Oncology and Palliative Medicine | Co-expression modules | Fusion protein | Next generation sequencing | MicroRNAs | Rhabdomyosarcoma | PRIMARY TUMORS | MUSCLE-SPECIFIC MICRORNA | DOWN-REGULATION | FUSION GENE | PEDIATRIC RHABDOMYOSARCOMA | SKELETAL-MUSCLE | ONCOLOGY | EMBRYONAL RHABDOMYOSARCOMA | ALVEOLAR RHABDOMYOSARCOMA | BINDING-SITES | EXPRESSION SIGNATURE | Paired Box Transcription Factors - genetics | Oncogene Proteins, Fusion - metabolism | Humans | Gene Expression Regulation, Neoplastic | Databases, Genetic | MicroRNAs - metabolism | Gene Regulatory Networks | Rhabdomyosarcoma, Embryonal - genetics | Transfection | Rhabdomyosarcoma, Alveolar - metabolism | Biomarkers, Tumor - metabolism | Rhabdomyosarcoma, Alveolar - pathology | Rhabdomyosarcoma, Embryonal - pathology | Genetic Predisposition to Disease | Reproducibility of Results | Rhabdomyosarcoma, Alveolar - genetics | Neoplasm Invasiveness | Computational Biology | Gene Expression Profiling - methods | Gene Fusion | Phenotype | Rhabdomyosarcoma, Embryonal - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Biomarkers, Tumor - genetics | High-Throughput Nucleotide Sequencing | MicroRNAs - genetics | Paired Box Transcription Factors - metabolism | Cell Movement | MicroRNA | Sarcoma | Genes | Genetic research | Muscles | Metastasis | Gene expression | Cytokines | Leukemia | Genomes | Roles | Inflammation | Metabolism | Muscle contraction | Cell adhesion & migration | Children & youth | Proteins | Morphogenesis | Signal transduction | Musculoskeletal system | Cell cycle | Cytoskeleton | Extracellular matrix | Software | Localization | Systems development | Deoxyribonucleic acid--DNA | Cancer | Index Medicus | RMS, rhabdomyosarcoma | MiRNAs, microRNAs | Original
Journal Article