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Antimicrobial Agents & Chemotherapy, ISSN 0066-4804, 12/2001, Volume 45, Issue 12, pp. 3462 - 3467
The effects of Klebsiella pneumoniae endotoxin on the biliary excretion and renal handling of rhodamine-123 were investigated in rats at different times after... 
rhodamine-123
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 2012, Volume 39, Issue 8, pp. 1128 - 1136
Journal Article
Brain Research, ISSN 0006-8993, 07/2019, Volume 1715, pp. 176 - 181
To investigate the mechanisms underlying the neuroprotective effect of tacrolimus (FK506) on the hippocampal neurons of rats with status epilepticus (SE). A... 
Oxidative stress | Mitochondrial pathway of apoptosis | Tacrolimus | Status epilepticus | Nitric oxide | SEIZURES | NITRIC-OXIDE | CALCINEURIN | FK506 | EXPRESSION | NEUROSCIENCES | RHODAMINE-123
Journal Article
Chemical Science, ISSN 2041-6520, 2018, Volume 9, Issue 12, pp. 3159 - 3164
Radiation therapy (RT) has been widely used for malignant tumor treatment. However, the large dosage of ionizing radiation and high frequency of radiotherapy... 
IN-VITRO | PHOTODYNAMIC THERAPY | INDUCED APOPTOSIS | CANCER-TREATMENT | OLIGOMYCIN | RADIOTHERAPY | CHEMISTRY, MULTIDISCIPLINARY | RHODAMINE-123 | MEMBRANE PERMEABILIZATION | ATP-SYNTHASE | LIVING CELLS
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 05/2018, Volume 16, Issue 18, pp. 3382 - 3388
A series of benzothiazolium-based hemicyanines (3a-3f) have been synthesized. Evaluation of their photophysical properties shows that they exhibit improved... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2017, Volume 139, Issue 47, pp. 17022 - 17030
In vivo quantitative measurement of biodistribution plays a critical role in the drug/probe development and diagnosis/treatment process monitoring. In this... 
APOPTOSIS | PHOTODYNAMIC THERAPY | IN-VIVO | LIGHT-UP PROBE | PROLIFERATION | DYSFUNCTION | LIVE CELLS | CANCER | CHEMISTRY, MULTIDISCIPLINARY | RHODAMINE-123 | LIVING CELLS | Mitochondria | Analysis | Raman effect
Journal Article
Chemical Communications, ISSN 1359-7345, 07/2015, Volume 51, Issue 58, pp. 11721 - 11724
A mitochondria-targeting probe, by conjugating a quaternary ammonium cation with glucosamine modified pH-activated cyanine, was designed and synthesized. This... 
CELLS | DRUG-DELIVERY | MITOCHONDRIAL | RETENTION | IN-VIVO | ACCUMULATION | CANCER | EXPRESSION | CARCINOMA | CHEMISTRY, MULTIDISCIPLINARY | RHODAMINE-123 | Membranes | Stability | Fluctuation | Imaging | Fluorescence | Signal to noise ratio | Tumors
Journal Article
Cell Death and Disease, ISSN 2041-4889, 11/2012, Volume 3, Issue 11, pp. e430 - e430
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2019, Volume 172, pp. 71 - 94
In this study, a new series of bis(alkanol)amine aryl ester heterodimers was synthesized and studied. The new compounds were designed based on the structures... 
1-(3-dimethylaminopropyl)-3-ethylcarbodiimmide hydrochloride | BCRP modulators | 4-Dimethylaminopyridine | Doxorubicin | Breast cancer resistance protein | Molecular docking | PDB | Ketoprofen Ethyl Ester | MDR reversers | Colorectal adenocarcinoma cells | ATPase activity | DMAP | Pirarubicin uptake | MDCK | Rhodamine-123 | PBS | BCRP | Human plasma stability | MRP1 | P-gp | EDCI | Topological polar surface area | KEE | DOX | TPSA | P-glycoprotein | Protein data bank | Rhd123 | P-gp modulators | Phosphate buffer solution | Madin-Darby Canin Kidney | MRP1 modulators | Multidrug resistance associated protein 1 | Rhodamine-123 efflux | Apparent permeability | Caco-2 cells | CELLS | CHEMISTRY, MEDICINAL | MECHANISM | EFFICACY | INHIBITION | KINETICS | DRUG EFFLUX | ABC TRANSPORTERS | ACCUMULATION | ANTHRACYCLINES | VERAPAMIL | Amines - chemistry | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Antineoplastic Agents - chemical synthesis | Drug Resistance, Multiple - drug effects | Humans | Neoplasm Proteins - antagonists & inhibitors | Structure-Activity Relationship | Neoplasm Proteins - metabolism | Esters - chemical synthesis | Dose-Response Relationship, Drug | Esters - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Tumor Cells, Cultured | ATP Binding Cassette Transporter, Subfamily G, Member 2 - antagonists & inhibitors | Dimerization | Caco-2 Cells | Models, Molecular | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Amines - chemical synthesis | Antineoplastic Agents - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | K562 Cells | Amines - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Esters - pharmacology | Drug Resistance, Neoplasm - drug effects
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 940 - 10
A quantitative technique to detect cancer in single cells could transform cancer diagnosis. Current cancer diagnosis utilizes histopathology, which requires... 
CELLS | FINE-NEEDLE-ASPIRATION | MULTIDISCIPLINARY SCIENCES | BIOPSY | SIZE | DYNAMICS | CYTOLOGY | TUMORS | RHODAMINE-123 | Fluorescence polarization | Mitochondria | Fluorescence | Breast cancer | Diagnosis | Medical diagnosis | Localization | Cancer | Methylene blue
Journal Article
Chemical Science, ISSN 2041-6520, 01/2018, Volume 9, Issue 12, pp. 3159 - 3164
Radiation therapy (RT) has been widely used for malignant tumor treatment. However, the large dosage of ionizing radiation and high frequency of radiotherapy... 
Gold | Mitochondria | Ionizing radiation | Radiation therapy | Titanium dioxide | Radiation dosage | Apoptosis
Journal Article
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 35, pp. 18205 - 18216
F16 is a novel identified delocalized lipophilic cation (DLC) which has been found to inhibiting a variety of tumor cell proliferation due to its selective... 
TARGET | SITE | SPECTROSCOPIC APPROACH | MECHANISM | DNA | MITOCHONDRIA | PROTEIN-BINDING | CELL | CHEMISTRY, MULTIDISCIPLINARY | RHODAMINE-123
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 01/2019, Volume 30, Issue 1, pp. 210 - 217
Herein, we developed a near-infrared (NIR) fluorescent probe for mitochondrial staining based on the NIR fluorochrome, silicon-rhodamine. The hydrophobicity of... 
OXYGEN | FUSION | RETENTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | DYSFUNCTION | FISSION | CHEMISTRY, MULTIDISCIPLINARY | RHODAMINE-123 | DELIVERY | Rhodamine | Amines | Fluorescence | Staining | Fluorescent indicators | Hydrophobicity | Chemical compounds | Cells | Molecules | Mitochondria | Conjugation | Hydrophobic surfaces | Cancer
Journal Article
Dalton Transactions, ISSN 1477-9226, 11/2014, Volume 43, Issue 44, pp. 16872 - 16879
Two phosphorescent iridium(III) complexes conjugated to a lipophilic triphenylphosphonium cation moiety, IrMitoOlivine and IrMitoNIR, were synthesized. The... 
REPLACEMENT | APOPTOSIS | OXIDATIVE STRESS | 2-PHOTON FLUORESCENT-PROBE | ZINC IONS | HYDROGEN-PEROXIDE | BINDING | CATION | RHODAMINE-123 | MOLECULES | CHEMISTRY, INORGANIC & NUCLEAR | Irradiation | Cations | Phosphorescence | Confocal | Lasers | Imaging
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 18, pp. 3382 - 3388
A series of benzothiazolium-based hemicyanines (3a-3f) have been synthesized. Evaluation of their photophysical properties shows that they exhibit improved... 
APOPTOSIS | INTACT-CELLS | MYELIN | MULTIPLE-SCLEROSIS | MEMBRANE | BIOLOGY | CHEMISTRY, ORGANIC | FLUORESCENT-PROBES | FLOW-CYTOMETRY | RHODAMINE-123 | LIVING CELLS | Mitochondria | Synthesis | Wavelengths | Organic solvents | Aqueous environments | Fluorescence | Staining | Fluorescent indicators | Probes
Journal Article
Biochemistry, ISSN 0006-2960, 04/2018, Volume 57, Issue 15, pp. 2184 - 2188
Drug efflux and enzymatic drug degradation are two cellular mechanisms that contribute to drug resistance in many cancers. Herein, we report the synthesis and... 
CARCINOMA-CELLS | PROTECTIVE IMMUNITY | TRANSPORTERS | ALPHA-MANNOSIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | INDUCTION | MULTIDRUG-RESISTANCE | RHODAMINE-123 | P-GLYCOPROTEIN | PRODRUG THERAPY | Drug resistance in microorganisms | Usage | Care and treatment | Immunotherapy | Imidazole | Quinoline | Chemical properties
Journal Article
CARCINOGENESIS, ISSN 0143-3334, 07/2009, Volume 30, Issue 7, pp. 1115 - 1124
We previously demonstrated that Bis[(2-oxindol-3-ylimino)-2-(2-aminoethyl) pyridine-N, N'] copper(II) [Cu(isaepy)(2)] was an efficient inducer of the apoptotic... 
CARCINOMA-CELLS | ANTICARCINOMA ACTIVITY | ONCOLOGY | MEMBRANE | REDUCTASE | TUMOR-CELLS | SELECTIVE DAMAGE | ACCUMULATION | STRESS | CYTOTOXICITY | RHODAMINE-123
Journal Article
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