Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2253) 2253
Publication (442) 442
Book Chapter (70) 70
Book Review (24) 24
Conference Proceeding (9) 9
Dissertation (5) 5
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
biochemistry & molecular biology (1029) 1029
index medicus (794) 794
ribosomal-subunit (514) 514
models, molecular (423) 423
crystal-structure (415) 415
rna (410) 410
animals (395) 395
humans (376) 376
cell biology (368) 368
escherichia-coli (357) 357
proteins (357) 357
nucleic acid conformation (349) 349
molecular sequence data (325) 325
angstrom resolution (297) 297
large ribosomal-subunit (292) 292
biophysics (286) 286
protein biosynthesis (275) 275
base sequence (269) 269
ribosomal subunits (245) 245
article (244) 244
ribosomes - metabolism (232) 232
research (215) 215
analysis (208) 208
ribosomes (208) 208
translation (202) 202
30s ribosomal-subunit (201) 201
microbiology (196) 196
protein binding (191) 191
messenger-rna (189) 189
rna - chemistry (185) 185
saccharomyces-cerevisiae (178) 178
amino acid sequence (177) 177
molecular biology (175) 175
binding sites (172) 172
binding (164) 164
protein (162) 162
protein conformation (157) 157
multidisciplinary sciences (155) 155
phylogeny (155) 155
antibiotics (152) 152
rna, messenger - metabolism (152) 152
biology (137) 137
crystallography, x-ray (134) 134
physiological aspects (134) 134
translation initiation (134) 134
dna (130) 130
gene expression (130) 130
mutation (127) 127
ribosome (127) 127
protein synthesis (124) 124
ribosomal-subunits (121) 121
yeast (121) 121
life sciences (119) 119
ribosomal-subunit rna (119) 119
protein-synthesis (118) 118
protein structure, tertiary (113) 113
bacteria (108) 108
biochemistry (108) 108
ribosomes - chemistry (106) 106
genetics & heredity (105) 105
rna, messenger - genetics (105) 105
research article (104) 104
escherichia coli - genetics (103) 103
evolution (101) 101
ribosomal proteins - metabolism (101) 101
genetic aspects (100) 100
structural basis (100) 100
anti-bacterial agents - pharmacology (99) 99
structure (97) 97
escherichia coli (96) 96
ribosomal proteins (96) 96
saccharomyces cerevisiae - metabolism (95) 95
secondary structure (93) 93
chemistry, multidisciplinary (90) 90
complex (89) 89
identification (89) 89
rna - metabolism (89) 89
recognition (86) 86
saccharomyces cerevisiae - genetics (85) 85
biochemical research methods (84) 84
saccharomyces cerevisiae proteins - metabolism (84) 84
40s ribosomal-subunit (83) 83
nucleotides (83) 83
genes (82) 82
molecular structure (82) 82
cryoelectron microscopy (81) 81
structure-activity relationship (81) 81
messenger rna (80) 80
ribonucleic acid--rna (80) 80
in-vivo (79) 79
base pairing (77) 77
biotechnology & applied microbiology (77) 77
escherichia coli - metabolism (77) 77
genetic translation (77) 77
gene (76) 76
transfer-rna (76) 76
transcription (75) 75
crystallography (74) 74
kinetics (74) 74
rrna (74) 74
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2273) 2273
Japanese (9) 9
Russian (9) 9
Chinese (7) 7
German (3) 3
Spanish (3) 3
French (2) 2
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text The resolution revolution
by Kühlbrandt, Werner
Science, ISSN 0036-8075, 2014, Volume 343, Issue 6178, pp. 1443 - 1444
  Precise knowledge of the structure of macromolecules in the cell is essential for understanding how they function. Structures of large macromolecules can now... 
ANGSTROM RESOLUTION | CRYO-EM | LARGE RIBOSOMAL-SUBUNIT | MULTIDISCIPLINARY SCIENCES | Electron microscopes | Microscopy | Molecular biology | Crystal structure
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Activity of rx-04 pyrrolocytosine protein synthesis inhibitors against multidrug-resistant gram-negative bacteria
by Vickers, Anna and Mushtaq, Shazad and Woodford, Neil and Doumith, Michel and Livermorea, David M
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 08/2018, Volume 62, Issue 8
Pyrrolocytosines RX-04A to -D are designed to bind to the bacterial 50S ribosomal subunit differently from currently used antibiotics. The four analogs had... 
Blasticidin | Pyrrolocytosine | Mcr-1 | 50S ribosomal subunit
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome
by Tan, SJ and Kermasson, L and Hoslin, A and Jaako, P and Faille, A and Acevedo-Arozena, A and Lengline, E and Ranta, D and Poiree, M and Fenneteau, O and le Pointe, HD and Fumagalli, S and Beaupain, B and Nitschke, P and Bole-Feysot, C and de Villartay, JP and Bellanne-Chantelot, C and Donadieu, J and Kannengiesser, C and Warren, AJ and Revy, P
BLOOD, ISSN 0006-4971, 07/2019, Volume 134, Issue 3, pp. 277 - 290
Shwachman-Diamond syndrome (SDS) is a recessive disorder typified by bone marrow failure and predisposition to hematological malignancies. SDS is predominantly... 
GENE | NEUTROPENIA | BONE-MARROW | GUIDELINES | SBDS | CLASSIFICATION | CHROMOSOME-20 | HEMATOLOGY | MARROW FAILURE | PROTEIN-SYNTHESIS | 60S RIBOSOMAL-SUBUNIT
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
by Cech, Thomas R and Steitz, Joan A
Cell, ISSN 0092-8674, 03/2014, Volume 157, Issue 1, pp. 77 - 94
Noncoding RNAs (ncRNAs) accomplish a remarkable variety of biological functions. They regulate gene expression at the levels of transcription, RNA processing,... 
SELF-SPLICING RNA | DOUBLE-STRANDED-RNA | MESSENGER-RNA | SMALL NUCLEOLAR RNAS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION TERMINATION CONTROL | ESCHERICHIA-COLI | GENE-EXPRESSION | 30S RIBOSOMAL-SUBUNIT | COGNATE TRANSFER-RNA | CELL BIOLOGY | Chromatin - metabolism | RNA, Untranslated - metabolism | Humans | RNA, Catalytic - metabolism | Gene Expression Regulation | Ribonucleoproteins - metabolism | RNA, Untranslated - genetics | Animals | RNA, Untranslated - chemistry | Ribonucleoproteins - chemistry | Genome | RNA, Catalytic - chemistry | RNA, Long Noncoding - metabolism | Chromatin - chemistry | Catalytic RNA | Genes | Genomics | Antisense RNA | Genetic transcription | Genetic translation | Telomerase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text How cryo-EM is revolutionizing structural biology
by Bai, Xiao-chen and McMullan, Greg and Scheres, Sjors H.W
Trends in Biochemical Sciences, ISSN 0968-0004, 01/2015, Volume 40, Issue 1, pp. 49 - 57
For many years, structure determination of biological macromolecules by cryo-electron microscopy (cryo-EM) was limited to large complexes or low-resolution... 
image processing | 3D reconstruction | maximum-likelihood optimization | macromolecular complexes | single-particle analysis | cryo-electron microscopy | electron detection | Image processing | Maximum-likelihood optimization | Macromolecular complexes | Electron detection | Single-particle analysis | Cryo-electron microscopy | PROTEIN CRYSTALS | CRYOELECTRON MICROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SINGLE-PARTICLE RECONSTRUCTION | ESCHERICHIA-COLI | ACTIVE PIXEL SENSOR | ATOMIC-RESOLUTION | TRANSMISSION ELECTRON-MICROSCOPY | 3-DIMENSIONAL RECONSTRUCTION | ANGSTROM RESOLUTION | LARGE RIBOSOMAL-SUBUNIT | Cryoelectron Microscopy | Macromolecular Substances - chemistry | Image Processing, Computer-Assisted | Imaging, Three-Dimensional - methods | Crystallography, X-Ray | Protein Conformation | Molecular Biology - methods
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Biallelic mutations in DNAJC21 cause Shwachman-Diamond syndrome
by Dhanraj, Santhosh and Matveev, Anna and Li, Hongbing and Lauhasurayotin, Supanun and Jardine, Lawrence and Cada, Michaela and Zlateska, Bozana and Tailor, Chetankumar S and Zhou, Joseph and Mendoza-Londono, Roberto and Vincent, Ajoy and Durie, Peter R and Scherer, Stephen W and Rommens, Johanna M and Heon, Elise and Dror, Yigal
Blood, ISSN 0006-4971, 03/2017, Volume 129, Issue 11, pp. 1557 - 1562
Abstract There is an Inside Blood Commentary on this article in this issue. 
DIAGNOSIS | PROTEIN | SBDS | PHENOTYPE | MATURATION | CHAPERONE | HEMATOLOGY | SACCHAROMYCES-CEREVISIAE | BONE-MARROW FAILURE | DEFICIENCY | 60S RIBOSOMAL-SUBUNIT
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites
by Espah Borujeni, Amin and Channarasappa, Anirudh S and Salis, Howard M
Nucleic Acids Research, ISSN 0305-1048, 02/2014, Volume 42, Issue 4, pp. 2646 - 2659
The ribosome's interactions with mRNA govern its translation rate and the effects of post-transcriptional regulation. Long, structured 5' untranslated regions... 
MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SEQUENCE | AUTOMATED DESIGN | SECONDARY STRUCTURE | SYNTHETIC BIOLOGY | BINDING | INITIATION COMPLEX | RIBOSOMAL-SUBUNIT | THERMODYNAMIC PARAMETERS | RNA Folding | Genome, Bacterial | 5' Untranslated Regions | Escherichia coli - genetics | Base Sequence | Molecular Sequence Data | Ribosomes - metabolism | Models, Genetic | Peptide Chain Initiation, Translational | Binding Sites | RNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text The mechanism of eukaryotic translation initiation and principles of its regulation
by Pestova, Tatyana V and Hellen, Christopher U. T and Jackson, Richard J
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 02/2010, Volume 11, Issue 2, pp. 113 - 127
Protein synthesis is principally regulated at the initiation stage (rather than during elongation or termination), allowing rapid, reversible and spatial... 
MESSENGER-RNA TRANSLATION | OPEN READING FRAME | 40S RIBOSOMAL-SUBUNIT | FUNCTIONAL INTERACTION | BINDING COMPLEX ELF4F | START CODON SELECTION | IN-VIVO | POLY(A)-BINDING PROTEIN | DEPENDENT TRANSLATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | Eukaryotic Initiation Factors - chemistry | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | RNA-Binding Proteins - genetics | Protein Biosynthesis | Humans | Eukaryota - chemistry | Gene Expression Regulation | Eukaryota - metabolism | Animals | Eukaryota - genetics | MicroRNAs - genetics | RNA-Binding Proteins - metabolism | Physiological aspects | Protein biosynthesis | Research | Binding proteins | Genetic translation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Activity of RX-04 Pyrrolocytosine Protein Synthesis Inhibitors against Multidrug-Resistant Gram-Negative Bacteria
by Vickers, A and Mushtaq, S and Woodford, N and Doumith, M and Livermore, DM
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 08/2018, Volume 62, Issue 8
Pyrrolocytosines RX-04A to -D are designed to bind to the bacterial 505 ribosomal subunit differently from currently used antibiotics. The four analogs had... 
blasticidin | pyrrolocytosine | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | 50S ribosomal subunit | mcr-1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts
by Schwaid, Adam G and Cornella-Taracido, Ivan
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2018, Volume 61, Issue 5, pp. 1767 - 1773
Compound potency is a key metric that is often used to drive medicinal chemistry programs. Compound potency is also taken into account when identifying the... 
LYSOSOMES | CHEMISTRY, MEDICINAL | MECHANISM | TARGET ENGAGEMENT | IN-VIVO | 50S RIBOSOMAL-SUBUNIT | INHIBITORS | TRANSLATION | BINDING | LEFLUNOMIDE | DISCOVERY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
by Sonenberg, Nahum and Hinnebusch, Alan G
Cell, ISSN 0092-8674, 2009, Volume 136, Issue 4, pp. 731 - 745
Translational control in eukaryotic cells is critical for gene regulation during nutrient deprivation and stress, development and differentiation, nervous... 
MESSENGER-RNA TRANSLATION | 40S RIBOSOMAL-SUBUNIT | CAENORHABDITIS-ELEGANS | BIOCHEMISTRY & MOLECULAR BIOLOGY | START CODON SELECTION | BINDING-PROTEIN | INHIBITS TRANSLATION | DIET-INDUCED OBESITY | PROTEIN-SYNTHESIS | TERM SYNAPTIC PLASTICITY | CAP-INDEPENDENT TRANSLATION | CELL BIOLOGY | Peptide Initiation Factors - chemistry | Peptide Initiation Factors - metabolism | Animals | Humans | Gene Expression Regulation | Ribosomes - chemistry | Models, Molecular | Ribosomes - metabolism | Peptide Chain Initiation, Translational
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights