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A validated high-performance liquid chromatography method for the determination of rifampicin and desacetyl rifampicin in plasma and urine, 08/2004
OBJECTIVE: To standardize a high-performance liquid chromatography (HPLC) method for the determination of rifampicin (RMP) and its major metabolite desacetyl... 
ph04076 Rifampin, rifamycin, HPLC | Pharmacology
Journal
Full Length Research Paper - Optimization of industrial production of rifamycin B by Amycolatopsis mediterranei. I. The role of colony morphology and nitrogen sources in productivity, 12/2004
A systematic approach to process optimization for production of rifamycin B was applied to a strain of Amycolatopsis mediterranei . Examination of the growth... 
Rifamycin B, fermentation, biotechnology, Amycolatopsis mediterranei, strain selection
Journal
International Journal of Tuberculosis and Lung Disease, ISSN 1027-3719, 10/2018, Volume 22, Issue 10, pp. 1243 - 1244
Journal Article
Organic Letters, ISSN 1523-7060, 05/2014, Volume 16, Issue 10, pp. 2752 - 2755
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4147 - 15
Rifamycin antibiotics (Rifs) target bacterial RNA polymerases (RNAPs) and are widely used to treat infections including tuberculosis. The utility of these... 
MYCOBACTERIUM-TUBERCULOSIS | ANSAMYCINS | STRUCTURAL BASIS | NATURAL-PRODUCTS | DNA | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | TRANSCRIPTION | ALLOSTERIC MODULATION | RNA-POLYMERASE | RPOB MUTATIONS | DNA-Directed RNA Polymerases - antagonists & inhibitors | Rifampin - chemistry | Humans | Metagenomics - methods | Tuberculosis - microbiology | Mycobacterium tuberculosis - drug effects | Antibiotics, Antitubercular - biosynthesis | Rifamycins - chemistry | Hydroxybenzoates - chemistry | Molecular Structure | Drug Resistance, Bacterial - drug effects | Drug Resistance, Bacterial - genetics | Mycobacterium tuberculosis - metabolism | Bacterial Proteins - antagonists & inhibitors | Bacteria - metabolism | Soil Microbiology | Bacterial Proteins - genetics | DNA-Directed RNA Polymerases - genetics | Antibiotics, Antitubercular - pharmacology | Bacteria - genetics | Antibiotics, Antitubercular - chemistry | Rifamycins - pharmacology | Aminobenzoates - chemistry | Tuberculosis - prevention & control | Bacterial Proteins - metabolism | Mutation | Rifampin - pharmacology | DNA-Directed RNA Polymerases - metabolism | Mycobacterium tuberculosis - genetics | Rifampin - metabolism | Phenotypes | Gene clusters | Congeners | Microbiomes | Biosynthesis | Rifamycin | Ribonucleic acid--RNA | Rifamycins | Substrates | Soil resistance | Tuberculosis | Antibiotics | Metabolites | Bacteria | Rifampin
Journal Article
Full Length Research Paper - Optimization of industrial production of rifamycin B by Amycolatopsis mediterranei. III. Production in fedbatch mode in shake flasks, 12/2004
Optimization of the fermentation process using the gene amplified variant of Amycolatopsis mediterranei , NCH, in the fermentation medium F2 was carried out by... 
Rifamycin B, fermentation, biotechnology, Amycolatopsis mediterranei, optimization, fed-batch and physiological factors
Journal
Full Length Research Paper - Optimization of industrial production of rifamycin B by Amycolatopsis mediterranei. IV. Production in the fermentor, 12/2004
Optimization of the physical and physiological parameters of the fermentation process using the gene amplified variant of Amycolatopsis mediterranei (NCH) was... 
Rifamycin B, fermentor, biotechnology, Amycolatopsis mediterranei, optimization, fed-batch and process development
Journal
Full Length Research Paper - Optimization of industrial production of rifamycin B by Amycolatopsis mediterranei. II. The role of gene amplification and physiological factors in productivity in shake flasks, 12/2004
Amplification of gene expression of the most productive colony type of Amycolatopsis mediterranei strain N1 under stress of chloramphenicol, resulted in... 
Rifamycin B, fermentation, biotechnology, Amycolatopsis mediterranei, optimization, gene amplification, physiological factors
Journal
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60042
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2342 - 9
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 08/2018, Volume 12, Issue 8, p. e0006728
Journal Article
Journal Article
Journal Article