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Cell Death and Disease, 06/2012, Volume 3, Issue 6, p. e320
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 41, pp. E8788 - E8797
Dysfunction of microglia plays a fundamental role in the pathogenesis of Alzheimer’s disease (AD), the most common form of dementia. However, there is a lack... 
Inflammation | RIPK1 | Alzheimer’s disease | RIP1 | Microglia | Biological Sciences | PNAS Plus | inflammation | microglia
Journal Article
Oncogene, ISSN 0950-9232, 05/2014, Volume 33, Issue 19, pp. 2520 - 2530
Journal Article
Oncotarget, 2015, Volume 6, Issue 11, pp. 9061 - 9072
Journal Article
NATURE, ISSN 0028-0836, 03/2011, Volume 471, Issue 7338, pp. 363 - 363
Caspase-8 has two opposing biological functions-it promotes cell death by triggering the extrinsic pathway of apoptosis, but also has a survival activity, as... 
RIP1 KINASE | APOPTOSIS | ACTIVATION | HOMEOSTASIS | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | C-FLIP | RECEPTOR | CELL-DEATH | TRANSGENIC MICE | REQUIREMENT
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2019, Volume 33, Issue 1, pp. 942 - 952
The role for the NOD-like receptor (NLR) P3 inflammasome in enterovirus infection remains controversial. Available data suggest that the NLRP3 inflammasome is... 
Coxsackievirus | Inflammasome | Innate immune response | RIP1/RIP3 | PROTEIN | COXSACKIEVIRUS B3 INFECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | coxsackievirus | INNATE | NONCANONICAL INFLAMMASOME ACTIVATION | CLEAVAGE | CELL BIOLOGY | MAVS | INTERLEUKIN-18 | innate immune response | inflammasome | BIOLOGY | RIP3 | RIP1
Journal Article
by Yan, XY and Zhang, Y and Zhang, JJ and Zhang, LC and Liu, YN and Wu, Y and Xue, YN and Lu, SY and Su, J and Sun, LK
CANCER SCIENCE, ISSN 1349-7006, 07/2017, Volume 108, Issue 7, pp. 1405 - 1413
Platinum-based therapeutic strategies have been widely used in ovarian cancer treatment. However, drug resistance has greatly limited therapeutic efficacy.... 
NF-KB pathway | SIGNALING ADAPTER | CARCINOMA CELLS | ovarian cancer | PHOSPHORYLATION | DEATH | DRUG-RESISTANCE | AUTOPHAGY | Drug resistance | p62 | RIP1 KINASE | ONCOLOGY | IN-VIVO | SQSTM1 | NF-KAPPA-B | RIP1
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 12/2019, Volume 1865, Issue 12, p. 165552
Accumulating evidence indicates that necroptosis contributes to cardiovascular diseases. We recently reported suppression of autophagy by necroptotic signals... 
mTOR | Rapamycin | TNF-α | Necroptosis | Autophagy | RIP1
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2016, Volume 94, Issue 2
ABSTRACT Nicotine significantly promoted apoptosis in stages I, VII, VIII, and XI spermatogonia, stages I, VII, VIII, X, and XI spermatocytes, and stages I–V,... 
Trim27 hypomethylation | apoptosis | RIP1 deubiquitination | nicotine | spermatozoa
Journal Article
Journal of Plastic, Reconstructive & Aesthetic Surgery, ISSN 1748-6815, 10/2019, Volume 72, Issue 10, pp. 1661 - 1668
Hydrogen gas exists in the atmosphere and was previously considered an inert gas. It has been reported to have protective effects on tissue... 
Ischemia-reperfusion injury | RIP3 | Skin flap | Hydrogen | RIP1
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 05/2018, Volume 118, pp. 26 - 35
Journal Article
by Wu, P and Shi, K.J and An, J.J and Ci, Y.L and Li, F and Hui, K.Y and Yang, Y and Xu, C.M
Cell Death and Disease, 02/2014, Volume 5, Issue 2
Journal Article
Blood, ISSN 0006-4971, 04/2014, Volume 123, Issue 16, pp. 2562 - 2572
Loss of inhibitor of apoptosis proteins (IAPs), particularly cIAP1, can promote production of tumor necrosis factor (TNF) and sensitize cancer cell lines to... 
RIP1 KINASE | ACTIVATION | NECROSIS | NECROPTOSIS | ALPHA-DEPENDENT APOPTOSIS | CASPASE-8 | TNF-ALPHA | ANTAGONISTS | HEMATOLOGY | NF-KAPPA-B | CELL-DEATH
Journal Article
FEBS letters, ISSN 0014-5793, 12/2016, Volume 590, Issue 23, pp. 4381 - 4392
X-linked inhibitor of apoptosis (XIAP)-associated factor 1 (XAF1) is a cytokine-regulated, tumor necrosis factor (TNF) receptor-associated factor (TRAF)... 
inflammatory response | NF-κB | TRAF2 | XAF1 | TNF | RIP1
Journal Article
Journal Article