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1996, Industrial control, computers, and communications series, ISBN 0863801889, Volume 12, xv, 435
Book
1992, 1st ed., ISBN 9780412453403, ix, 261
Book
1992, ISBN 9780126491401, x, 328
Book
1993, IBM McGraw-Hill series., ISBN 9780077076870, xiii, 265
Book
1992, ISBN 0133884147, xiv, 386
Book
1994, Updated edition, 1994. --, ISBN 1566070023, iv, 153
Book
1991, Prentice Hall series in innovative technology., ISBN 0138756341, xxiv, 288
Book
ACS Chemical Biology, ISSN 1554-8929, 01/2011, Volume 6, Issue 1, pp. 47 - 60
In the 12 years since the process of RNA interference (RNAi) was first discovered, great progress has been made in understanding its mechanism and exploiting... 
siRNA or miRNA seed sequence | RISC | microRNA (miRNA) | GENOME-WIDE RNAI | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE IMMUNE-RESPONSE | Short interfering RNA (siRNA) | FUNCTIONAL DISSECTION | MAMMALIAN-CELLS | DEPENDENT STIMULATION | SMALL INTERFERING RNAS | MESSENGER-RNAS | RNA Interference | RNAI off-target effect | GENE-EXPRESSION | C-ELEGANS | siRNA multiplicity validation | HIV-1 REPLICATION | RNA, Small Interfering - genetics | Gene Expression | Down-Regulation | Genomics | RNA, Messenger - genetics | Untranslated Regions | Validation Studies as Topic | Transcription, Genetic | MicroRNAs - genetics | RNA, Double-Stranded - chemistry | Genetic Techniques - standards | RNA, Small Interfering - metabolism | Short interfering RNA (siRNA): An endogenous or artificial (synthetic) small double strand RNA with perfect pairing of the two strands. One strand (called the guide strand) targets RISC to perfectly complementary mRNAs, resulting in endonucleolytic cleavage of the mRNA by the RISC component Ago2 | siRNA or miRNA seed sequence: The 5′ region of the guide strand of an siRNA or miRNA sequence, extending from nucleotides 2–7 (hexamer) or 2–8 (heptamer) | or mRNA decay | siRNA multiplicity validation: Validation of a gene-phenotype association by showing that the phenotype can be produced by multiple independent siRNAs that target different regions of the same mRNA | MicroRNA (miRNA): A mature endogenous small double strand RNA, often with imperfect pairing of the two strands, originating from processing of a precursor RNA molecule by cellular RNases. miRNAs target RISC complexes to sites that have imperfect sequence complementarity, and that are typically located in the 3′ untranslated region of the mRNA | RISC: The RNA-Induced Silencing Complexes are multi-protein complexes containing an Argonaute protein, a small single strand RNA and additional regulatory proteins | RNA interference: A cellular process that downregulates gene expression at a post-transcriptional step. One strand of a small double strand RNA (siRNA or miRNA) integrates in a protein complex called RISC and targets an mRNA with sequence complementarity for cleavage, translation inhibition and | RNAi off-target effect: Any effect of an RNAi-based treatment that is a consequence of reducing the expression of an unintended target
Journal Article
2016, Second edition., ISBN 9780081006344
Web Resource
1989, Electrical engineering and electronics, ISBN 0824781511, Volume 56, xiii, 371
Book
1994, McGraw-Hill computer science series., ISBN 0070204535, xix, 619
Book
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