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Nature Methods, ISSN 1548-7091, 11/2010, Volume 7, Issue 11, pp. 901 - 903
We describe a one-step, isothermal assembly method for synthesizing DNA molecules from overlapping oligonucleotides. The method cycles between in vitro... 
AUTOMATION | GENE SYNTHESIS | DNA | BIOCHEMICAL RESEARCH METHODS | Animals | DNA, Mitochondrial - chemical synthesis | Recombination, Genetic | Chromosomes, Artificial, Bacterial | Polymerase Chain Reaction | Mice | Genome, Mitochondrial | Chemical synthesis | Gene expression | Analysis | Transfer RNA | Mitochondria | Rodents | Genomics
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 9, pp. 2199 - 2220
The quinazolinone-containing 2,3-disubstituted piperidines febrifugine and isofebrifugine have been the subject of significant research efforts since their... 
Halofuginone | Anti-fibrotic | Dichroine A and B | 3-hydroxypiperidine | Isomerization | Febrifugine | Quinazolinone | Anti-angiogenic | Isofebrifugine | Anti-protozoal | SEMICYCLIC N,O-ACETALS | CHEMISTRY, MEDICINAL | LEWIS-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACROPHYLLA VAR. OTAKSA | CHEMISTRY, ORGANIC | NUCLEOPHILIC-SUBSTITUTION REACTIONS | HYDRANGEA-CHINENSIS | TRANSFER-RNA SYNTHETASE | ANTIMALARIAL ACTIVITY | CONCISE ENANTIOSELECTIVE SYNTHESIS | PLASMODIUM MALARIA PARASITE | CATALYTIC ASYMMETRIC-SYNTHESIS | Quinazolines - chemical synthesis | Piperidines - chemistry | Stereoisomerism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Plasmodium falciparum - drug effects | Piperidines - chemical synthesis | Cycloaddition Reaction | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Antimalarials - pharmacology | Quinazolinones - chemical synthesis | Animals | Cyclization | Piperidines - pharmacology | Antimalarials - chemistry | Quinazolinones - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolines - pharmacology | Quinazolines - chemistry | Antimalarials - chemical synthesis | Quinazolinones - pharmacology | Malaria | Chemical tests and reagents | RNA | Ammonium paratungstate | Aluminum compounds | Fluorides | Biological response modifiers | Transforming growth factors | Muscle proteins | Lipase | Cytokinins | Ammonium compounds | Pyridine | Dimethyl sulfoxide | Interferon | Chemical synthesis | Adenosine triphosphate
Journal Article
2013, 1. Aufl., ISBN 9781118007518, 918
Chemical Synthesis of Nucleoside Analoguesexamines the application of synthetic methodologies to the preparation of compounds of biological interest, including... 
Life Sciences | Biochemistry | SCIENCE | Nucleosides | Antiviral agents | Nucleosynthesis
eBook
Chemistry – A European Journal, ISSN 0947-6539, 04/2017, Volume 23, Issue 22, pp. 5210 - 5213
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2018, Volume 59, Issue 37, pp. 3423 - 3427
As an archetype -nucleoside, pyrazofurin possesses broad-spectrum antiviral and antitumor activities. However, the presence of the acidic enol in the... 
Phosphorylation | Pyrazofurin | Triphosphate | P(V)-N activation | ERROR CATASTROPHE | RNA | P(V)-N ACTIVATION STRATEGY | CHEMISTRY, ORGANIC | PYRAZOMYCINS | POLYPHOSPHATES | RIBAVIRIN | NUCLEOSIDE | METABOLISM | ANTIVIRAL ACTIVITY | DERIVATIVES | Phosphates | Nucleosides | Antiviral agents | Metabolites | Chemical synthesis | RNA polymerases
Journal Article
Organic Letters, ISSN 1523-7060, 09/2013, Volume 15, Issue 17, pp. 4386 - 4389
U1 snRNA is an interesting biological tool for splicing correction and regulation of gene expression. However, U1 snRNA has never been chemically synthesized.... 
NUCLEAR IMPORT | CHEMISTRY, ORGANIC | GENE | OLIGORIBONUCLEOTIDE | PRE-MESSENGER-RNA | RNA, Small Nuclear - chemistry | RNA Splicing | Molecular Structure | RNA, Messenger - metabolism | RNA, Small Nuclear - chemical synthesis | RNA, Messenger - genetics | Letter
Journal Article
by Zhu, LL and Hong, R
TETRAHEDRON LETTERS, ISSN 0040-4039, 05/2018, Volume 59, Issue 22, pp. 2112 - 2127
In this Digest paper, various approaches toward chemical synthesis of negamycin, a natural dipeptide-like antibiotic, were summarized. The strategy and tactics... 
READTHROUGH | ASYMMETRIC-SYNTHESIS | ACID | RNA | CHEMISTRY, ORGANIC | PROTEIN-SYNTHESIS | Total synthesis | DISCOVERY | (+)-NEGAMYCIN | ENANTIOSELECTIVE ROUTE | Bioactivity | Negamycin | TERMINATION | DERIVATIVES
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 06/2019, Volume 2019, Issue 23, pp. 3799 - 3805
Oligonucleotides containing nitroxide spin labels, used in biophysical studies of nucleic acids, are frequently prepared by chemical synthesis. However, during... 
Site‐directed spin labeling | Nitroxides | EPR spectroscopy | Oligonucleotides | Site-directed spin labeling | RNA | EPR | COMPLEXES | CHEMISTRY, ORGANIC | CONFORMATIONAL DYNAMICS | DISTANCE MEASUREMENTS | NUCLEOSIDE | SPECTROSCOPY | ELECTRON-PARAMAGNETIC-RESONANCE | Hydroxides | Chemical synthesis | Free radicals (Chemistry) | Analysis
Journal Article
Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 96, pp. 12938 - 12941
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 11/2005, Volume 3, Issue 21, pp. 3851 - 3868
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2013, Volume 288, Issue 2, pp. 1420 - 1427
It is a great privilege to contribute to the Reflections essays. In my particular case, this essay has allowed me to weave some of my major scientific... 
PHOSPHORAMIDITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYMER | RNA - chemical synthesis | DNA - chemical synthesis | RNA | Genomics | DNA | RNA Synthesis | Proteomics | Reflections | DNA Synthesis
Journal Article