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1. Full Text NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
by Hirota, Simon A and Ng, Jeffrey and Lueng, Alan and Khajah, Maitham and Parhar, Ken and Li, Yan and Lam, Victor and Potentier, Mireille S and Ng, Kelvin and Bawa, Misha and McCafferty, Donna‐Marie and Rioux, Kevin P and Ghosh, Subrata and Xavier, Ramnik J and Colgan, Sean P and Tschopp, Jurg and Muruve, Daniel and MacDonald, Justin A and Beck, Paul L
Inflammatory Bowel Diseases, ISSN 1078-0998, 06/2011, Volume 17, Issue 6, pp. 1359 - 1372
Background: Attenuated innate immune responses to the intestinal microbiota have been linked to the pathogenesis of Crohn's disease (CD). Recent genetic... 
microbiota | NLRP3 | neutrophil | inflammasome | defensin | NITRIC-OXIDE SYNTHASE | ULCERATIVE-COLITIS | RIBOSOMAL-RNA | ILEAL CROHNS-DISEASE | ALPHA-DEFENSIN EXPRESSION | BOWEL-DISEASE | NALP3 INFLAMMASOME | HUMAN BETA-DEFENSIN-2 | PERIODIC SYNDROMES | PANETH CELLS | GASTROENTEROLOGY & HEPATOLOGY | Carrier Proteins - physiology | Interleukin-1beta - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Transforming Growth Factor beta - physiology | Interleukin-10 - physiology | Inflammasomes - physiology | Animals | Chemotaxis - physiology | Colitis - physiopathology | Thiophenes | Immunity, Innate - physiology | Homeostasis - physiology | Furans | Mice | Apoptosis - physiology | Intestines - physiology | Disease Models, Animal | Animal models | Inflammatory bowel diseases | Immune response | muramyl dipeptide | Homeostasis | Antimicrobial agents | Data processing | Crohn's disease | Leukocytes (neutrophilic) | Macrophages | Secretions | Chemotaxis | Interleukin 18 | Sodium | Intestine | Interleukin 10 | Dextran sulfate | Colitis | Intestinal microflora | Mutation | Growth factors | Apoptosis | Immune system
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2. Full Text Bimodal expression of PHO84 is modulated by early termination of antisense transcription
by Castelnuovo, Manuele and Rahman, Samir and Guffanti, Elisa and Infantino, Valentina and Stutz, Françoise and Zenklusen, Daniel
Nature Structural and Molecular Biology, ISSN 1545-9993, 07/2013, Volume 20, Issue 7, pp. 851 - 858
Many Saccharomyces cerevisiae genes encode antisense transcripts, some of which are unstable and degraded by the exosome component Rrp6. Loss of Rrp6 results... 
CRYPTIC UNSTABLE TRANSCRIPTS | PERVASIVE TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERGENIC TRANSCRIPTION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | BIOPHYSICS | BINDING PROTEINS NRD1 | GENE-EXPRESSION | POLY(A) POLYMERASE | POLYMERASE-II TRANSCRIPTS | BIDIRECTIONAL PROMOTERS | RNA DEGRADATION | Saccharomyces cerevisiae - genetics | Multiprotein Complexes | Saccharomyces cerevisiae Proteins - biosynthesis | RNA, Messenger - metabolism | Promoter Regions, Genetic - genetics | RNA, Messenger - biosynthesis | RNA Helicases - physiology | Transcription, Genetic | RNA, Fungal - genetics | Gene Expression Regulation, Fungal | RNA-Binding Proteins - physiology | In Situ Hybridization, Fluorescence | Exosome Multienzyme Ribonuclease Complex - physiology | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Polynucleotide Adenylyltransferase - physiology | Proton-Phosphate Symporters - genetics | RNA, Antisense - metabolism | Polyadenylation | Metalloendopeptidases - physiology | Models, Genetic | Nuclear Proteins - physiology | Saccharomyces cerevisiae Proteins - physiology | Histone Deacetylases - physiology | Proton-Phosphate Symporters - biosynthesis | Histone-Lysine N-Methyltransferase - physiology | DNA Helicases - physiology | RNA, Antisense - genetics | Cytogenetics | Research | Genetic transcription | DNA methylation | Gene expression | Molecular biology | Ribonucleic acid--RNA | Rrp6 | Nrd1-Nab3-Sen1 | transcription termination | PHO84 regulation | antisense RNA | yeast | single molecule FISH | antisense 3′ end processing
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3. Full Text Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
by Mari Ohnuki and Koji Tanabe and Kenta Sutou and Ito Teramoto and Yuka Sawamura and Megumi Narita and Michiko Nakamura and Yumie Tokunaga and Masahiro Nakamura and Akira Watanabe and Shinya Yamanaka and Kazutoshi Takahashi
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12426 - 12431
Pluripotency can be induced in somatic cells by overexpressing transcription factors, including POU class 5 homeobox 1 (OCT3/4), sex determining region Y-box 2... 
Phenotypes | Induced pluripotent stem cells | Somatic cells | Stem cells | Retroviridae | Embryonic stem cells | Pluripotent stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | Epigenetics | Retrotransposon | Evolution | NONCODING RNA-ROR | ROADBLOCK | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | evolution | INDUCTION | epigenetics | IPS CELLS | PLURIPOTENT STEM-CELLS | PATHWAY | HUMAN FIBROBLASTS | retrotransposon | EXPRESSION | Octamer Transcription Factor-3 - physiology | Endogenous Retroviruses - physiology | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Endogenous Retroviruses - genetics | Pluripotent Stem Cells - virology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA, Viral - antagonists & inhibitors | RNA, Viral - genetics | SOXB1 Transcription Factors - genetics | Embryonic Stem Cells - virology | SOXB1 Transcription Factors - physiology | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Cellular Reprogramming - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - virology | Pluripotent Stem Cells - physiology | Kruppel-Like Transcription Factors - physiology | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | RNA, Long Noncoding - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Cellular Reprogramming - physiology | Epigenetic inheritance | Transcription factors | Retroviruses | Physiological aspects | Genetic research | Genetic aspects | Research | Cell differentiation | Gene expression | Virus research | Biological Sciences
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4. Full Text Immunity in Drosophila melanogaster-from microbial recognition to whole-organism physiology
by Buchon, Nicolas and Buchon, Nicolas and Silverman, Neal and Cherry, Sara
Nature Reviews Immunology, ISSN 1474-1733, 12/2014, Volume 14, Issue 12, pp. 796 - 810
Since the discovery of antimicrobial peptide responses 40 years ago, the fruit fly Drosophila melanogaster has proven to be a powerful model for the study of... 
RNA INTERFERENCE | SIGNALING PATHWAY | TOLL PATHWAY | ANTIMICROBIAL PEPTIDE GENES | HOST-DEFENSE | BACTERIAL-INFECTION | IMMUNOLOGY | ANTIVIRAL IMMUNITY | TRANSCRIPTION FACTOR RELISH | GUT IMMUNITY | INNATE IMMUNITY | Immunity, Innate - immunology | Drosophila melanogaster - microbiology | Animals | Drosophila melanogaster - immunology | Microbiota - immunology | Age Factors | Signal Transduction | Reactive Oxygen Species - immunology | Digestive System - immunology | Drosophila Proteins - immunology | Genetic aspects | Immune response | Properties | Drosophila | Antimicrobial peptides
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5. Brown fat biology and thermogenesis
by Richard, Denis and Picard, Frederic
Frontiers in Bioscience, ISSN 1093-9946, 01/2011, Volume 16, Issue 4, pp. 1233 - 1260
Brown fat (brown adipose tissue, BAT) primary function is to produce heat. There is now compelling evidence to indicate that brown fat cells in some BAT depots... 
Human | Brain | Energy balance | Obesity | White adipose tissue | Mouse | Rat | Uncoupling protein 1 | Energy expenditure | Brown adipose tissue | Review | ACTIVATED RECEPTOR-GAMMA | BETA-ADRENERGIC-RECEPTORS | Brown Adipose Tissue | MESSENGER-RNA EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED THERMOGENESIS | IN-SITU HYBRIDIZATION | Energy Balance | CELL BIOLOGY | WHITE ADIPOSE-TISSUE | AGOUTI-RELATED PROTEIN | MITOCHONDRIAL UNCOUPLING PROTEIN | White Adipose Tissue | CENTRAL-NERVOUS-SYSTEM | Uncoupling Protein 1 | MELANIN-CONCENTRATING HORMONE | Energy Expenditure | Humans | Dorsomedial Hypothalamic Nucleus - physiology | Male | Ion Channels - physiology | PPAR gamma | Melanocortins - physiology | Thermogenesis - physiology | Cannabinoid Receptor Modulators - physiology | Sympathetic Nervous System - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Neurons - physiology | Adult | Female | Preoptic Area - physiology | Myoblasts - physiology | Cold Temperature | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Ion Channels - biosynthesis | Melanins - physiology | Adipose Tissue, Brown - physiology | Mitochondrial Proteins - physiology | Mitochondrial Proteins - biosynthesis | Pituitary Hormones - physiology | Hypothalamic Hormones - physiology | Adipocytes, White - physiology | Cell Lineage | Adipose Tissue, Brown - cytology | Adipocytes, Brown - physiology | Animals | Energy Metabolism | Diabetes Mellitus - physiopathology | Sex Factors | Fluorodeoxyglucose F18 | Uncoupling Protein 2 | Heat-Shock Proteins - physiology
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6. HIV transmission through breastfeeding: a review of available evidence
by Newell, Marie-Louise and World Health Organization (WHO) and United Nations . Joint Programme on HIV/AIDS (UNAIDS) and United Nations . Population Fund (UNFPA) and United Nations . Children's Fund (UNICEF)
2004, ISBN 9241562714, 25
AIDS (Disease) in infants -- Prevention | Infants -- Health and hygiene | Breastfeeding -- Health aspects | Infants -- Nutrition | AIDS (Disease) -- Transmission
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7. Full Text MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
by Ting Zhao and Jian Li and Alex F. Chen
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 07/2010, Volume 299, Issue 1, pp. 110 - 116
Endothelial progenitor cells (EPCs) play an important role in angiogenesis, which is essential for numerous physiological processes as well as tumor growth.... 
PHYSIOLOGY | EMERGING ROLES | MIR-34A | GROWTH ARREST | ENDOCRINOLOGY & METABOLISM | DOWN-REGULATION | PHENOTYPE | DYSFUNCTION | SIRT1 | EXPRESSION | CANCER | CALORIE RESTRICTION | RNA, Small Interfering - genetics | Antigens, CD34 - analysis | Nerve Tissue Proteins - analysis | Male | Forkhead Transcription Factors - physiology | Stem Cells - cytology | RNA - genetics | Antigens, CD - analysis | Vascular Endothelial Growth Factor Receptor-2 - physiology | Endothelial Cells - physiology | Nerve Tissue Proteins - physiology | Vascular Endothelial Growth Factor Receptor-2 - analysis | Peptides - physiology | Gene Expression Regulation | Cellular Senescence - physiology | Rats | RNA - chemistry | Reverse Transcriptase Polymerase Chain Reaction | AC133 Antigen | Glycoproteins - physiology | Rats, Sprague-Dawley | Sirtuin 1 - antagonists & inhibitors | Blotting, Western | Antigens, CD34 - physiology | Neovascularization, Physiologic - physiology | Animals | Endothelial Cells - cytology | Sirtuin 1 - physiology | Forkhead Transcription Factors - analysis | Antigens, CD - physiology | Stem Cells - physiology | MicroRNAs - genetics | Glycoproteins - analysis | MicroRNAs - physiology | RNA, Small Interfering - administration & dosage | Peptides - analysis | Genetic aspects | Cell physiology | MicroRNA | Neovascularization | Properties | Endothelium
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8. Full Text Physiology of astroglia
by Verkhratsky, Alexei and Nedergaard, Maiken
Physiological Reviews, ISSN 0031-9333, 01/2018, Volume 98, Issue 1, pp. 239 - 389
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are... 
ASTROCYTES IN-SITU | PHYSIOLOGY | MESSENGER-RNA EXPRESSION | FIBRILLARY ACIDIC PROTEIN | IDENTIFIED GLIAL-CELLS | CENTRAL-NERVOUS-SYSTEM | VOLTAGE-GATED SODIUM | GLUTAMATE-RECEPTOR ACTIVATION | GAMMA-AMINOBUTYRIC-ACID | NICOTINIC ACETYLCHOLINE-RECEPTORS | METHYL-D-ASPARTATE | Astrocytes - cytology | Biological Evolution | Astrocytes - physiology | Animals | Ion Channels - metabolism | Membrane Potentials | Humans | Homeostasis | Receptors, Cell Surface - metabolism | Higher Nervous Activity - physiology | Physiology | Research | Astrocytes | Analysis | Central nervous system | Review
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