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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 4, pp. 1512 - 1517
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 26, pp. 17465 - 17474
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Journal of Virology, ISSN 0022-538X, 2014, Volume 88, Issue 15, pp. 8194 - 8200
Journal Article
The Journal of Immunology, ISSN 0022-1767, 09/2005, Volume 175, Issue 5, pp. 2851 - 2858
The cellular protein retinoic acid-inducible gene I (RIG-I) senses intracellular viral infection and triggers a signal for innate antiviral responses including... 
ACTIVATION | VIRUS | GENE | RNA HELICASE | PHOSPHORYLATION | POSITIVE FEEDBACK | IRF-3 | INDUCTION | IMMUNOLOGY | EXPRESSION | VIRAL-INFECTION | Protein Structure, Tertiary | DEAD Box Protein 58 | Animals | DEAD-box RNA Helicases | RNA Helicases - physiology | Virus Diseases - immunology | Signal Transduction | Humans | Mice | RNA Helicases - chemistry | Immunity, Innate | Interferon-Induced Helicase, IFIH1
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2016, Volume 62, Issue 4, pp. 586 - 602
RIG-I and MDA5 sense virus-derived short 5′ppp blunt-ended or long dsRNA, respectively, causing interferon production. Non-signaling LGP2 appears to positively... 
ASSEMBLES | RNA HELICASE LGP2 | DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FILAMENT | CHICKEN | RIG-I | SIGNAL-ACTIVATION | INNATE IMMUNE SENSOR | PARAMYXOVIRUS V PROTEINS | INSIGHTS | CELL BIOLOGY | Interferon-Induced Helicase, IFIH1 - chemistry | RNA-Binding Proteins - genetics | DEAD Box Protein 58 - metabolism | Interferon-Induced Helicase, IFIH1 - genetics | Humans | Structure-Activity Relationship | Avian Proteins - chemistry | Receptors, Pattern Recognition - metabolism | Transfection | DEAD Box Protein 58 - genetics | Adenosine Triphosphate - metabolism | Protein Interaction Domains and Motifs | RNA, Double-Stranded - metabolism | Nucleic Acid Conformation | Binding Sites | RNA, Double-Stranded - chemistry | Cell Line | DEAD Box Protein 58 - chemistry | Avian Proteins - metabolism | Receptors, Pattern Recognition - chemistry | RNA-Binding Proteins - chemistry | Adenosine Triphosphatases - metabolism | Interferon-Induced Helicase, IFIH1 - metabolism | Models, Molecular | Hydrolysis | Animals | Chickens | RNA, Double-Stranded - genetics | Protein Binding | Receptors, Pattern Recognition - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Adenosine Diphosphate - metabolism | RNA-Binding Proteins - metabolism | Avian Proteins - genetics | Oligomers | RNA | Crystals | Interferon | Structure | Biological response modifiers | Molecular biology | Life Sciences | Biomolecules | Innate immunity | Immunology | Biochemistry, Molecular Biology
Journal Article