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Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 21, pp. 12214 - 12240
...), located downstream of the 5' splice site (5' ss) of exon 7. Here, we describe a novel approach to exon 7 splicing modulation through activation of a cryptic 5' ss (Cr1... 
DISTANCE | U1 SNRNP | SURVIVAL MOTOR-NEURON | SMALL NUCLEAR-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRONIC STRUCTURE | SELECTION | CRITICAL EXON | SMN GENE | SINGLE NUCLEOTIDE | PRE-MESSENGER-RNA | Gene regulation, Chromatin and Epigenetics
Journal Article
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2008, Volume 135, Issue 7, pp. 1224 - 1236
...% of genes encoding two or more isoforms. In most cases, the molecular mechanisms responsible for splice site choice remain poorly understood... 
RNA | PROTEINS | DNA | COMPLEX | U1 SNRNP | BIOCHEMISTRY & MOLECULAR BIOLOGY | SR PROTEINS | IN-VIVO | GENE-EXPRESSION | SEX-LETHAL | HNRNP A1 | PREMESSENGER RNA | EXON RECOGNITION | PRE-MESSENGER-RNA | CELL BIOLOGY | RNA Splice Sites | Alternative Splicing | Exons | Models, Biological | Humans | Gene Expression Regulation | HeLa Cells | Genetic Techniques
Journal Article
Journal Article
Nucleic acids research, ISSN 1362-4962, 2019, Volume 47, Issue 2, pp. 911 - 928
...), but they are often poorly spliced. To identify the underlying mechanisms for this phenomenon, we searched for putative splicing inhibitory sequences using the ncRNA-a2 as a model... 
HUMAN GENOME | TRANSCRIPTOME | ALTERNATIVE EXON | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | ENHANCER | MECHANISMS | IDENTIFICATION | PRE-MESSENGER-RNA | REVEALS | Pyrimidines - analysis | RNA Splicing | RNA Splice Sites | Introns | Humans | Serine-Arginine Splicing Factors - metabolism | HeLa Cells | RNA, Long Noncoding - metabolism | RNA and RNA-protein complexes
Journal Article