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Science, ISSN 0036-8075, 8/2012, Volume 337, Issue 6098, pp. 1111 - 1115
Journal Article
Annual Review of Genetics, ISSN 0066-4197, 12/2011, Volume 45, Issue 1, pp. 273 - 297
Bacteria and archaea have evolved defense and regulatory mechanisms to cope with various environmental stressors, including virus attack. This arsenal has been... 
RNAi | immunity | interference | bacteriophage | coevolution | Bacteriophage | Coevolution | Immunity | Interference | MYCOBACTERIUM-TUBERCULOSIS | ESCHERICHIA-COLI | PROVIDES ACQUIRED-RESISTANCE | REPEATS CRISPRS | IMMUNE-SYSTEM | GENOME SEQUENCE | ANTIVIRAL DEFENSE | STRUCTURAL BASIS | YERSINIA-PESTIS | GENETICS & HEREDITY | HORIZONTAL GENE-TRANSFER | RNA, Archaeal - immunology | Bacteria - chemistry | RNA, Archaeal - chemistry | Bacterial Proteins - chemistry | Archaea - chemistry | Virus Diseases - virology | Genetic Loci | Archaea - virology | Bacteria - immunology | RNA Interference | RNA, Small Untranslated - chemistry | Bacteriophages - genetics | RNA, Bacterial - genetics | RNA, Small Untranslated - genetics | Transcription, Genetic | Archaea - immunology | Bacterial Proteins - immunology | RNA, Archaeal - genetics | Virus Diseases - genetics | Bacteria - virology | Adaptive Immunity | Virus Diseases - immunology | RNA Processing, Post-Transcriptional | Plasmids - immunology | RNA, Small Untranslated - immunology | Bacterial Proteins - genetics | Computational Biology | Gene Expression Regulation, Archaeal | Endodeoxyribonucleases - chemistry | Bacteria - genetics | Bacteriophages - immunology | Endodeoxyribonucleases - genetics | Escherichia coli Proteins | RNA, Bacterial - chemistry | RNA, Bacterial - immunology | Archaea - genetics | CRISPR-Associated Proteins | Gene Expression Regulation, Bacterial | Evolution, Molecular | RNA | Physiological aspects | Bacteria | Genetic aspects | Research | Genetic regulation | Archaeabacteria
Journal Article
Nature, ISSN 0028-0836, 2011, Volume 474, Issue 7351, pp. 385 - 389
Live vaccines have long been known to trigger far more vigorous immune responses than their killed counterparts(1-6). This has been attributed to the ability... 
TRANSCRIPTION FACTORS | PHAGOSOME | PROTECTIVE IMMUNITY | ACTIVATION | T-CELL RESPONSES | RECOGNITION | MULTIDISCIPLINARY SCIENCES | INFLAMMASOME | TOLL-LIKE RECEPTORS | INNATE | REGULATORS | Phagosomes - microbiology | RNA, Messenger - immunology | Inflammasomes - metabolism | Interferon-beta - immunology | Bacterial Vaccines - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Adaptor Proteins, Vesicular Transport - deficiency | Microbial Viability - immunology | Bacteria - immunology | Phagosomes - immunology | Interferon-beta - genetics | RNA, Bacterial - genetics | Macrophages - immunology | Macrophages - microbiology | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Microbial Viability - genetics | Adaptor Proteins, Vesicular Transport - immunology | Macrophages - cytology | Bacteria - genetics | Virulence Factors | Immunity, Innate - immunology | Vaccines, Attenuated - immunology | Vaccines, Inactivated - immunology | Animals | Carrier Proteins - metabolism | Bacterial Vaccines - immunology | Inflammasomes - immunology | Dendritic Cells - microbiology | RNA, Bacterial - immunology | Antibodies, Bacterial - immunology | Bacteria - pathogenicity | Dendritic Cells - cytology | Mice | Phagocytosis | Vaccines, Attenuated - genetics | Proteins | Bacteria | Microbiology | Kinases | Immune system | toll-like receptors | transcription factors | inflammasome | innate | recognition | phagosome | t-cell responses | activation | regulators | protective immunity
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2016, Volume 22, Issue 11, pp. 1277 - 1284
Bacterial infection is highly prevalent in patients who have had a stroke. Despite the potential contribution of micro-aspiration in post-stroke pneumonia, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | VENTILATOR-ASSOCIATED PNEUMONIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOTA | CELL BIOLOGY | STROKE | ASPIRATION PNEUMONIA | TRAUMATIC BRAIN-INJURY | RESISTANCE | CENTRAL-NERVOUS-SYSTEM | STAPHYLOCOCCUS-AUREUS | COMPLICATIONS | DYSFUNCTION | Enterococcus faecalis | Bacteremia - immunology | Gram-Positive Bacterial Infections - immunology | Humans | Middle Aged | Male | Infarction, Middle Cerebral Artery - immunology | Pneumonia, Bacterial - metabolism | Gram-Positive Bacterial Infections - metabolism | Bacteremia - microbiology | Adrenergic beta-Antagonists - pharmacology | Urinary Tract Infections - metabolism | Bacterial Infections - immunology | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Zonula Occludens-1 Protein - metabolism | Receptors, Adrenergic, beta - metabolism | Bacterial Infections - microbiology | Stroke - immunology | Disease Models, Animal | Permeability - drug effects | Pneumonia, Bacterial - microbiology | Specific Pathogen-Free Organisms | Blood Culture | Intestine, Small - microbiology | Computational Biology | Bacterial Translocation - immunology | Gastrointestinal Microbiome - genetics | Goblet Cells - metabolism | Bacteremia - metabolism | Animals | Sequence Analysis, RNA | Intestine, Small - cytology | Microbiota - genetics | Intestine, Small - drug effects | RNA, Ribosomal, 16S - genetics | Pneumonia, Bacterial - immunology | Aged | High-Throughput Nucleotide Sequencing | Mice | Intestine, Small - metabolism | Urinary Tract Infections - immunology | Bacterial Infections - metabolism | Goblet Cells - cytology | Stroke (Disease) | Ribosomal RNA | Bacteria, Pathogenic | Physiological aspects | Genetic aspects | Virulence (Microbiology) | Identification and classification | Stroke | Pneumonia | Bacterial infections
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2012, Volume 31, Issue 21, pp. 4153 - 4164
Immunity against infection with Listeria monocytogenes is not achieved from innate immune stimulation by contact with killed but requires viable Listeria... 
inflammasome activation | innate immunity | Listeria infection | nucleic‐acid secretion | protective immunity | nucleic-acid secretion | AIM2 INFLAMMASOME | CELLS | ACTIVATION | PROTEIN | RECOGNITION | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTOGENES INFECTION | CELL BIOLOGY | PATHWAY | IMMUNE-RESPONSES | Cytoplasm - metabolism | DNA, Bacterial - immunology | Listeria monocytogenes - immunology | Interferon-Induced Helicase, IFIH1 | DEAD-box RNA Helicases - physiology | Flow Cytometry | Listeriosis - immunology | RNA, Bacterial - genetics | Membrane Proteins - metabolism | DEAD-box RNA Helicases - metabolism | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Macrophages - microbiology | Cytoplasm - microbiology | DEAD Box Protein 58 | Inflammation - microbiology | Signal Transduction | Listeriosis - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | DEAD-box RNA Helicases - genetics | Immunity, Cellular - immunology | Animals | DNA, Bacterial - genetics | Cytoplasm - immunology | CARD Signaling Adaptor Proteins | Adaptor Proteins, Signal Transducing - genetics | Fluorescent Antibody Technique | Listeria monocytogenes - genetics | RNA, Bacterial - immunology | Listeriosis - microbiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Signal transduction | Interferon | Bacterial infections | Molecular biology | Immune system
Journal Article