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Journal Article
Science, ISSN 0036-8075, 09/2014, Volume 345, Issue 6201, pp. 1139 - 1145
Many RNA regulatory proteins controlling pre-messenger RNA splicing contain serine: arginine (SR) repeats. Here, we found that these SR domains bound hydrogel... 
INTRANUCLEAR DISTRIBUTION | MULTIDISCIPLINARY SCIENCES | EXPANSION | SEQUENCE | ALS | HEXANUCLEOTIDE REPEAT | GRANULES | PROTEIN-KINASES | FOCI | SR SPLICING FACTORS | DEGENERATION | Phosphorylation | Protein Biosynthesis | Alternative Splicing | Protein-Tyrosine Kinases - metabolism | Humans | Astrocytes - pathology | Glutamate Plasma Membrane Transport Proteins - genetics | Frontotemporal Dementia - metabolism | RNA, Messenger - biosynthesis | Repetitive Sequences, Amino Acid | Hydrogel, Polyethylene Glycol Dimethacrylate | Cell Nucleolus - metabolism | RNA, Messenger - antagonists & inhibitors | Cell Death | Transcription, Genetic | C9orf72 Protein | Dipeptides - metabolism | Protein-Serine-Threonine Kinases - metabolism | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Protein Structure, Tertiary | Amyotrophic Lateral Sclerosis - genetics | Dipeptides - pharmacology | Cells, Cultured | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | RNA, Ribosomal - antagonists & inhibitors | RNA, Antisense - biosynthesis | Proteins - genetics | Amyotrophic Lateral Sclerosis - pathology | RNA, Antisense - antagonists & inhibitors | Amyotrophic Lateral Sclerosis - metabolism | RNA, Ribosomal - biosynthesis | Dipeptides - genetics | Astrocytes - metabolism | Cell death | Ribonucleoproteins | Genetic research | Genetic aspects | Research | Properties | RNA splicing | Proteins | Amyotrophic lateral sclerosis | Biosynthesis | Polypeptides | Ribonucleic acid--RNA | Apoptosis | Index Medicus | Neurological diseases | Ribonucleic acids | Peptides | Toxicity | Genes | Drosophila | Genetics
Journal Article
eLife, ISSN 2050-084X, 12/2018, Volume 7
Replication-dependent (RD) core histone mRNA produced during S-phase is the only known metazoan protein-coding mRNA presenting a 3'stem-loop instead of the... 
endoribonuclease | cell biology | histone pre-mRNA 3' end processing | chromosomes | metallo β-lactamase | S-phase | human | gene expression | MBL domain containing protein 1 | COMPLEX | PROTEIN | METALLO-BETA-LACTAMASE | BIOLOGY | 3'-END MATURATION | POLYADENYLATION FACTOR CPSF-73 | CELL-CYCLE | CLEAVAGE | POLY(A) | FAMILY | REVEALS | Endoribonucleases - chemistry | Endoribonucleases - genetics | Humans | Histones - biosynthesis | Substrate Specificity | Crystallography, X-Ray | S Phase Cell Cycle Checkpoints | RNA, Messenger - biosynthesis | beta-Lactamases - genetics | Cloning, Molecular | Escherichia coli - metabolism | HEK293 Cells | Protein Interaction Domains and Motifs | beta-Lactamases - metabolism | Binding Sites | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | Mutagenesis, Site-Directed | Endoribonucleases - metabolism | Genetic Vectors - chemistry | RNA, Messenger - genetics | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Sequence Homology, Amino Acid | beta-Lactamases - chemistry | Sequence Alignment | Histones - genetics | Protein Conformation, beta-Strand | Escherichia coli - genetics | Protein Binding | HeLa Cells | Kinetics | Physiological aspects | Biosynthesis | Messenger RNA | Observations | CRISPR | Enzymes | Cloning | Cyclin-dependent kinases | mRNA | Kinases | Proteins | E coli | Polyadenylation | Cell cycle | Endonuclease | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 2010, Volume 70, Issue 11, pp. 4528 - 4538
MicroRNA-21 (miR-21) was reported to be overexpressed and contributes to invasion and gemcitabine resistance in pancreatic ductal adenocarcinoma (PDAC). The... 
SURVIVAL | CELLS | INVASION | METASTASIS | INHIBITION | ONCOLOGY | PHOSPHORYLATION | POOR-PROGNOSIS | ADENOCARCINOMA | EXPRESSION PROFILES | CHEMOTHERAPY | Vascular Endothelial Growth Factor A - biosynthesis | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Humans | Middle Aged | Carcinoma, Pancreatic Ductal - metabolism | Apoptosis - genetics | Carcinoma, Pancreatic Ductal - genetics | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | RNA, Messenger - biosynthesis | Deoxycytidine - therapeutic use | Matrix Metalloproteinase 9 - genetics | Aged, 80 and over | Adult | Retrospective Studies | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Matrix Metalloproteinase 2 - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Cell Growth Processes - drug effects | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | PTEN Phosphohydrolase - biosynthesis | MicroRNAs - biosynthesis | Pancreatic Neoplasms - genetics | Treatment Outcome | Carcinoma, Pancreatic Ductal - pathology | Proto-Oncogene Proteins c-akt - biosynthesis | Carcinoma, Pancreatic Ductal - drug therapy | Matrix Metalloproteinase 2 - genetics | Antimetabolites, Antineoplastic - therapeutic use | Cell Line, Tumor | Aged | MicroRNAs - genetics | Deoxycytidine - analogs & derivatives | Index Medicus
Journal Article
Genome Biology, ISSN 1474-7596, 11/2016, Volume 17, Issue 1, pp. 231 - 231
Journal Article
by Andersson, Robin and Gebhard, Claudia and Miguel-Escalada, Irene and Hoof, Ilka and Bornholdt, Jette and Boyd, Mette and Chen, Yun and Zhao, Xiaobei and Schmidl, Christian and Suzuki, Takahiro and Ntini, Evgenia and Arner, Erik and Valen, Eivind and Li, Kang and Schwarzfischer, Lucia and Glatz, Dagmar and Raithel, Johanna and Lilje, Berit and Rapin, Nicolas and Bagger, Frederik Otzen and Jørgensen, Mette and Andersen, Peter Refsing and Bertin, Nicolas and Rackham, Owen and Burroughs, A. Maxwell and Baillie, J. Kenneth and Ishizu, Yuri and Shimizu, Yuri and Furuhata, Erina and Maeda, Shiori and Negishi, Yutaka and Mungall, Christopher J and Meehan, Terrence F and Lassmann, Timo and Itoh, Masayoshi and Kawaji, Hideya and Kondo, Naoto and Kawai, Jun and Lennartsson, Aneas and Daub, Carsten O and Heutink, Peter and Hume, David A and Jensen, Torben Heick and Suzuki, Harukazu and Hayashizaki, Yoshihide and Müller, Ferenc and Forrest, Alistair R. R and Carninci, Piero and Rehli, Michael and Sandelin, Albin and de Hoon, Michiel J. L and Haberle, Vanja and Kulakovskiy, Ivan V and Lizio, Marina and Mungall, Christoher J and Schmeier, Sebastian and Dimont, Emmanuel and Schmid, Christian and Schaefer, Ulf and Medvedeva, Yulia A and Plessy, Charles and Vitezic, Morana and Severin, James and Semple, Colin A and Young, Robert S and Francescatto, Margherita and Alam, Intikhab and Albanese, Davide and Altschuler, Gabriel M and Arakawa, Takahiro and Archer, John A. C and Arner, Peter and Babina, Magda and Rennie, Sarah and Balwierz, Piotr J and Beckhouse, Anthony G and Pradhan-Bhatt, Swati and Blake, Judith A and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessano and Briggs, James and Brombacher, Frank and Califano, Anea and Cannistracti, Carlo V and Carbajo, Daniel and Chierici, Marco and Ciani, Yari and Clevers, Hans C and Dalla, Emiliano and Davis, Carrie A and Detmar, Michael and Diehl, Alexander D and Dohi, Taeko and bløs, Finn and Edge, Albert S. B and Edinger, Matthias and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and ... and FANTOM Consortium and The FANTOM Consortium
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7493, pp. 455 - 461
Journal Article