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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 523 - 530.e9
Background There is evidence that gene expression of innate immunity receptors is upregulated by farming-related exposures. Objective We sought to determine... 
Allergy and Immunology | nutrition | childhood | prenatal | farming | farm milk | Toll-like receptors | Innate immunity | CD14 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | RNA, Messenger - immunology | Prospective Studies | Humans | Immunity, Innate - genetics | Prenatal Exposure Delayed Effects - prevention & control | Infant | Male | Maternal Exposure | RNA, Messenger - biosynthesis | Rural Population | Fetal Blood - chemistry | Gene Expression - immunology | Hypersensitivity, Immediate - immunology | Adult | Female | Surveys and Questionnaires | Agriculture | Milk - immunology | Polymorphism, Single Nucleotide - immunology | Fetal Blood - immunology | Cats | Toll-Like Receptors - immunology | Hypersensitivity, Immediate - genetics | Lipopolysaccharide Receptors - immunology | Hypersensitivity, Immediate - prevention & control | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Immunity, Innate - immunology | Animals | Prenatal Exposure Delayed Effects - immunology | Toll-Like Receptors - genetics | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide - genetics | Medical colleges | Pregnant women | Analysis | Genes | Environmental health | Genetic research | Respiratory tract diseases | Gene expression | Allergic reaction | Biometry | Public health | Disease | Rural areas | Farm buildings | Allergies | Asthma | Hay fever | Womens health | Questionnaires | Age | Immune system | Farming | Index Medicus | Abridged Index Medicus | Neonates | Inventories | TLR7 protein | TLR5 protein | Hypersensitivity | Single-nucleotide polymorphism | Regression analysis | TLR4 protein | CD14 antigen | Gene polymorphism | Immunity | Rural environments | TLR9 protein | Cord blood | Farms | Pasture | Prenatal experience | Food | Milk | Prenatal Exposure Delayed Effects | Antigens, CD14 | Hypersensitivity, Immediate | Life Sciences | Toll-Like Receptors | Pulmonology and respiratory tract | Gene Expression | Immunity, Innate | Human health and pathology | Polymorphism, Single Nucleotide | RNA, Messenger | Fetal Blood
Journal Article
Nature (London), ISSN 1476-4687, 02/2017, Volume 543, Issue 7644, pp. 248 - 251
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 11/2015, Volume 182, Issue 2, pp. 220 - 229
Summary Adoptive T cell therapy of cancer employs a large number of ex‐vivo‐propagated T cells which recognize their targets either by virtue of their... 
constitutively active TLR‐4 | tumour‐infiltrating lymphocytes | CD8 T lymphocytes | mRNA electroporation | MRNA electroporation | Tumour-infiltrating lymphocytes | Constitutively active TLR-4 | Life Sciences & Biomedicine | Immunology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | RNA, Messenger - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Lectins, C-Type - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Lectins, C-Type - metabolism | Flow Cytometry | Transfection - methods | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Chemokines - immunology | Cytokines - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Cytokines - metabolism | RNA, Messenger - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Toll-Like Receptor 4 - genetics | Electroporation | Toll-Like Receptor 4 - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Interferon-gamma - immunology | K562 Cells | Cell Line, Tumor | Chemokines - metabolism | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Messenger RNA | Biological response modifiers | T cells | Melanoma | Tumor necrosis factor-TNF | T cell receptors | Cytokines | Lymphocytes | Index Medicus | Translational | constitutively active TLR-4 | tumour-infiltrating lymphocytes
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 11/2009, Volume 183, Issue 10, pp. 6681 - 6688
The alpha 7 nicotinic acetylcholine receptor (nAChR) was recently described as an anti-inflammatory target in both macrophages and T cells. Its expression by... 
Life Sciences & Biomedicine | Immunology | Science & Technology | GATA3 Transcription Factor - agonists | T-Box Domain Proteins - antagonists & inhibitors | Encephalomyelitis, Autoimmune, Experimental - immunology | NF-kappa B - metabolism | Interferon-gamma - metabolism | Interleukin-4 - agonists | RNA, Messenger - metabolism | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | GATA3 Transcription Factor - metabolism | Th1 Cells - drug effects | Antigen-Presenting Cells - metabolism | NF-kappa B - antagonists & inhibitors | Antigen-Presenting Cells - drug effects | Myelin-Oligodendrocyte Glycoprotein | T-Box Domain Proteins - metabolism | Interleukins - antagonists & inhibitors | Mice, Knockout | Spinal Cord - immunology | Interleukin-4 - immunology | Receptors, Nicotinic - immunology | Glycoproteins - immunology | Mice | alpha7 Nicotinic Acetylcholine Receptor | Tumor Necrosis Factor-alpha - metabolism | RNA, Messenger - immunology | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - metabolism | GATA3 Transcription Factor - immunology | Interleukin-17 - immunology | NF-kappa B - immunology | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Nicotine - pharmacology | Spinal Cord - pathology | Interleukins - immunology | Interferon-gamma - antagonists & inhibitors | Female | RNA, Messenger - drug effects | Receptors, Nicotinic - drug effects | Interleukin-4 - metabolism | Mice, Inbred C57BL | Antigen-Presenting Cells - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Interferon-gamma - immunology | Cell Proliferation - drug effects | Receptors, Nicotinic - genetics | CD4-Positive T-Lymphocytes - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Cancer immunology, immunotherapy, ISSN 1432-0851, 11/2005, Volume 55, Issue 7, pp. 808 - 818
This study was designed to determine the characteristics of tumour cell-derived microvesicles (TMV) and their interactions with human monocytes. TMV were shed... 
Monocytes | Biomedicine | Immunology | Transfer | Oncology | Cancer Research | mRNA | CCR6 | Tumour-derived microvesicles | Life Sciences & Biomedicine | Science & Technology | RNA, Messenger - immunology | Adenocarcinoma - ultrastructure | Tetradecanoylphorbol Acetate - pharmacology | Humans | Neoplasm Proteins - immunology | RNA, Messenger - analysis | Cell Line, Tumor - drug effects | Gene Expression Profiling | Monocytes - immunology | Membrane Proteins - analysis | Basigin - genetics | Basigin - immunology | Antigens, Neoplasm - analysis | Neoplasm Proteins - genetics | Receptors, Chemokine | Receptors, Cytokine - genetics | Antigens, Neoplasm - immunology | Cell Survival | Adenocarcinoma - immunology | RNA, Messenger - genetics | HLA Antigens - immunology | Pancreatic Neoplasms - ultrastructure | Immunophenotyping | Membrane Proteins - immunology | Cell Membrane - ultrastructure | Neoplasms - ultrastructure | Chemotaxis | Hyaluronan Receptors - genetics | Particle Size | Cell Line, Tumor - ultrastructure | Lung Neoplasms - immunology | Colorectal Neoplasms - immunology | Neoplasms - immunology | Cell Line, Tumor - immunology | Pancreatic Neoplasms - immunology | Colorectal Neoplasms - ultrastructure | Lung Neoplasms - ultrastructure | Neoplasm Proteins - analysis | Receptors, Cytokine - immunology | Cell Membrane - immunology | Genes, MHC Class I | Hyaluronan Receptors - immunology | Apoptosis | Growth factors | Messenger RNA | Tumors | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 05/2011, Volume 474, Issue 7351, pp. 385 - 389
Live vaccines have long been known to trigger far more vigorous immune responses than their killed counterparts(1-6). This has been attributed to the ability... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phagosomes - microbiology | RNA, Messenger - immunology | Inflammasomes - metabolism | Interferon-beta - immunology | Bacterial Vaccines - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Adaptor Proteins, Vesicular Transport - deficiency | Microbial Viability - immunology | Bacteria - immunology | Phagosomes - immunology | Interferon-beta - genetics | RNA, Bacterial - genetics | Macrophages - immunology | Macrophages - microbiology | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Microbial Viability - genetics | Adaptor Proteins, Vesicular Transport - immunology | Macrophages - cytology | Bacteria - genetics | Virulence Factors | Immunity, Innate - immunology | Vaccines, Attenuated - immunology | Vaccines, Inactivated - immunology | Animals | Carrier Proteins - metabolism | Bacterial Vaccines - immunology | Inflammasomes - immunology | Dendritic Cells - microbiology | RNA, Bacterial - immunology | Antibodies, Bacterial - immunology | Bacteria - pathogenicity | Dendritic Cells - cytology | Mice | Phagocytosis | Vaccines, Attenuated - genetics | Proteins | Bacteria | Microbiology | Kinases | Immune system | Index Medicus | toll-like receptors | transcription factors | inflammasome | innate | recognition | phagosome | t-cell responses | activation | regulators | protective immunity
Journal Article
Nature immunology, ISSN 1529-2916, 06/2015, Volume 16, Issue 8, pp. 838 - 849
Interferon-gamma (IFN-gamma) primes macrophages for enhanced microbial killing and inflammatory activation by Toll-like receptors (TLRs), but little is known... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Toll-Like Receptor 2 - genetics | TOR Serine-Threonine Kinases - metabolism | Homeodomain Proteins - metabolism | Humans | Protein Biosynthesis - immunology | Eukaryotic Initiation Factor-4E - metabolism | Multiprotein Complexes - genetics | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | Base Sequence | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Macrophage Activation - immunology | Signal Transduction - genetics | Toll-Like Receptor 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - metabolism | Signal Transduction - drug effects | Toll-Like Receptor 2 - immunology | Protein Biosynthesis - drug effects | MicroRNAs - genetics | Multiprotein Complexes - immunology | RNA, Messenger - immunology | Transcription Factor HES-1 | Macrophage Activation - genetics | Intracellular Signaling Peptides and Proteins - immunology | Homeodomain Proteins - immunology | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | Eukaryotic Initiation Factor-4E - immunology | Protein Biosynthesis - genetics | Eukaryotic Initiation Factor-4E - genetics | Macrophages - immunology | RNA, Messenger - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Homeodomain Proteins - genetics | TOR Serine-Threonine Kinases - immunology | Interferon-gamma - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Macrophage Activation - drug effects | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Index Medicus
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 2011, Volume 23, Issue 3, pp. 399 - 406
Journal Article