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Journal Article
Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 1760, Volume 459, Issue 3, pp. 513 - 524
BIK (BCL2-interacting killer) is a pro-apoptotic BH3 (BCL2 homology domain 3)-only protein and a member of the BCL2 protein family. It was proposed recently... 
BCL2-interacting killer (BIK) | Extracellularsignal-regulated kinase 1/2 (ERK1/2) | BCL2-interacting mediator of cell death (BIM) | Cell cycle | Apoptosis | Proteasome | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Neoplasms - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | G1 Phase - drug effects | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins - biosynthesis | Proteolysis - drug effects | Ubiquitination - drug effects | Bcl-2-Like Protein 11 | RNA Interference | Apoptosis Regulatory Proteins - genetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Neoplasm Proteins - genetics | Apoptosis Regulatory Proteins - biosynthesis | Proto-Oncogene Proteins - metabolism | MAP Kinase Kinase 1 - antagonists & inhibitors | Proto-Oncogene Proteins - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Neoplasms - enzymology | Proteasome Endopeptidase Complex - chemistry | MAP Kinase Kinase 1 - metabolism | Proto-Oncogene Proteins - genetics | Cyclin-Dependent Kinase 6 - metabolism | MAP Kinase Kinase 2 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | Membrane Proteins - biosynthesis | MAP Kinase Signaling System - drug effects | Membrane Proteins - antagonists & inhibitors | MAP Kinase Kinase 2 - antagonists & inhibitors | Protein Stability - drug effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Proteasome Endopeptidase Complex - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12550 - 12565
Background: Silencing of long non-coding RNA (lncRNA) by microRNA (miRNA) has only been recently observed. Results: miR-141 binds to HOTAIR and suppresses its... 
HOTAIR | TRANSCRIPTIONAL ACTIVITY | CODING REGIONS | Genistein | ALPHA-AMANITIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICRORNA TARGETS | MIR-200 FAMILY | REPRESSORS ZEB1 | Invasion | Renal Carcinoma | Gene Regulation | Long Non-coding RNA | EPITHELIAL-MESENCHYMAL TRANSITION | MicroRNA | PROSTATE-CANCER | GENE-EXPRESSION | Cell Growth | Cancer Biology | miR-141 | MAMMALIAN MESSENGER-RNAS | Neoplasms - metabolism | Kidney Neoplasms - genetics | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Apoptosis - genetics | MicroRNAs - metabolism | Kidney Neoplasms - metabolism | Neoplasms - genetics | RNA Interference | Base Sequence | Cell Line | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | Carcinoma, Renal Cell - pathology | Neoplasm Invasiveness | RNA, Long Noncoding - genetics | Binding Sites - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Homeodomain Proteins - genetics | HT29 Cells | Transcription Factors - metabolism | Carcinoma, Renal Cell - metabolism | Cell Line, Tumor | Kidney Neoplasms - pathology | MicroRNAs - genetics | Mutation | Neoplasms - pathology | RNA, Long Noncoding - metabolism | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus | Cell Biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12791 - 12804
Background: Fibroblasts from patients with idiopathic pulmonary fibrosis (IPF) overexpress the urokinase-type plasminogen activator receptor (uPAR) and are... 
MIGRATION | LUNG FIBROSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | DOWN-REGULATION | CELL-ADHESION | Urokinase Receptor | Lipid Raft | Integrin | Fibrosis | LIPID RAFTS | GROWTH | IDIOPATHIC PULMONARY-FIBROSIS | Fibroblast | MYOFIBROBLAST DIFFERENTIATION | GLIOBLASTOMA CELLS | Integrin alpha5beta1 - genetics | Shc Signaling Adaptor Proteins - metabolism | Membrane Microdomains - metabolism | Humans | Receptors, Urokinase Plasminogen Activator - blood | Caveolins - metabolism | Idiopathic Pulmonary Fibrosis - blood | Caveolins - genetics | Idiopathic Pulmonary Fibrosis - metabolism | Proto-Oncogene Proteins c-fyn - genetics | RNA Interference | Fibroblasts - metabolism | Severity of Illness Index | Signal Transduction | Cells, Cultured | Urokinase-Type Plasminogen Activator - genetics | Blotting, Western | Fibronectins - metabolism | Receptors, Urokinase Plasminogen Activator - metabolism | Animals | Proto-Oncogene Proteins c-fyn - metabolism | Shc Signaling Adaptor Proteins - genetics | Urokinase-Type Plasminogen Activator - metabolism | Idiopathic Pulmonary Fibrosis - pathology | Protein Binding | Fibroblasts - cytology | Mice | Receptors, Urokinase Plasminogen Activator - genetics | Integrin alpha5beta1 - metabolism | Microscopy, Fluorescence | Cell Movement | Index Medicus | Glycobiology and Extracellular Matrices
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1768, Volume 289, Issue 19, pp. 13461 - 13474
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1782, Volume 289, Issue 21, pp. 14520 - 14533
Journal Article
The Journal of Pathology, ISSN 0022-3417, 08/2011, Volume 224, Issue 4, pp. 484 - 495
Journal Article
Urologic Oncology: Seminars and Original Investigations, ISSN 1078-1439, 2012, Volume 30, Issue 5, pp. 652 - 659
Abstract Bacillus Calmette-Guerin (BCG)-refractory generated a high risk to patients with bladder cancer during treatment. Tyrosine kinase receptor (TKR) and... 
Urology | Sutent | Synergism | Combined therapy | Bacillus Calmette-Guerin (BCG) | Apoptosis | PROTEIN | ANGIOGENESIS | SUPERFICIAL BLADDER-CANCER | ALPHA | THERAPY | ONCOLOGY | UROLOGY & NEPHROLOGY | MICE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Apoptosis - drug effects | Humans | BCG Vaccine - pharmacology | Vascular Endothelial Growth Factor A - genetics | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Urinary Bladder Neoplasms - genetics | Bcl-2-Like Protein 11 | Urinary Bladder Neoplasms - pathology | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Urinary Bladder Neoplasms - metabolism | Carcinoma, Transitional Cell - genetics | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Carcinoma, Transitional Cell - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Drug Synergism | Cell Movement - drug effects | Pyrroles - pharmacology | Carcinoma, Transitional Cell - pathology | Signal Transduction - drug effects | Cell Line, Tumor | bcl-X Protein - metabolism | Adenocarcinoma | Tyrosine | Adjuvant treatment | Antineoplastic agents | Bladder cancer | Cells | Antimitotic agents | Messenger RNA | Analysis | Vascular endothelial growth factor | Health aspects | Cancer | Index Medicus
Journal Article
Pathology International, ISSN 1320-5463, 11/2011, Volume 61, Issue 11, pp. 645 - 651
Lymphocyte‐rich gastric cancer (Ly‐rich GC) is characterized by lymphoid stroma. To understand its formation, we studied the expression of a chemokine ligand... 
chemokine | anti‐tumor immunity | CCR6 | gastric cancer | CCL20 | lymphoepithelioma‐like carcinoma | Chemokine | Lymphoepithelioma-like carcinoma | Gastric cancer | Anti-tumor immunity | DENDRITIC CELLS | INFILTRATING LYMPHOCYTES | RECEPTOR | PATHOLOGY | lymphoepithelioma-like carcinoma | COLORECTAL-CANCER | LIVER | <