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1. Full Text The 21-Nucleotide, but Not 22-Nucleotide, Viral Secondary Small Interfering RNAs Direct Potent Antiviral Defense by Two Cooperative Argonautes in Arabidopsis thaliana
by Xian-Bing Wang and Juan Jovel and Petchthai Udomporn and Ying Wang and Qingfa Wu and Wan-Xiang Li and Virginie Gasciolli and Herve Vaucheret and Shou-Wei Ding
The Plant cell, ISSN 1040-4651, 4/2011, Volume 23, Issue 4, pp. 1625 - 1638
RNA interference | MicroRNA | RNA | Gels | Antivirals | Small interfering RNA | Viruses | Viral RNA | Nucleotides | Plant cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Antiviral Agents - immunology | Plant Diseases - immunology | Gene Silencing | Immunity, Innate - genetics | Arabidopsis - immunology | Nucleotides - genetics | Cucumovirus - immunology | Mutation - genetics | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Immunity, Innate - immunology | Plant Diseases - virology | Argonaute Proteins | Protein Binding | Arabidopsis - virology | RNA-Binding Proteins - metabolism | Arabidopsis thaliana | Antiviral agents | Plant defenses | Physiological aspects | Genetic aspects | Research | Health aspects | Index Medicus | Disease resistance | Gene silencing | RNA viruses | RNA-mediated interference | siRNA | Argonaute 2 protein | RNA-directed RNA polymerase | Life Sciences | Plants genetics | Genetics
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2. Full Text Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
by de Fougerolles, Antonin and Hartmann, Gunther and Akira, Shizuo and Ablasser, Andrea and Manoharan, Muthiah and Schlee, Martin and Uematsu, Satoshi and Hornung, Veit and Bourquin, Carole and Guenthner-Biller, Margit and Endres, Stefan and Noronha, Anne
Nature medicine, ISSN 1078-8956, 03/2005, Volume 11, Issue 3, pp. 263 - 270
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Cell Line | Interferon-alpha - biosynthesis | Dendritic Cells - immunology | Humans | Toll-Like Receptor 9 | RNA, Viral - physiology | Toll-Like Receptor 7 | RNA, Small Interfering - chemistry | Toll-Like Receptors | Membrane Glycoproteins - physiology | Animals | RNA, Small Interfering - immunology | Base Sequence | Mice | Receptors, Cell Surface - physiology | Liposomes | Dendritic Cells - metabolism | RNA, Small Interfering - metabolism | Index Medicus
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3. Full Text Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages
by Qian, Yuan and Qiao, Sha and Dai, Yanfeng and Xu, Guoqiang and Dai, Bolei and Lu, Lisen and Yu, Xiang and Luo, Qingming and Zhang, Zhihong
ACS nano, ISSN 1936-0851, 09/2017, Volume 11, Issue 9, pp. 9536 - 9549
tumor-associated macrophage | small interfering RNA | dual-targeting | colony stimulating factor-1 receptor | cancer immunotherapy | Physical Sciences | Chemistry | Materials Science | Nanoscience & Nanotechnology | Technology | Materials Science, Multidisciplinary | Science & Technology - Other Topics | Chemistry, Multidisciplinary | Chemistry, Physical | Science & Technology | RNA, Small Interfering - genetics | Immunotherapy - methods | Macrophages - pathology | Nanoparticles - chemistry | Peptides - chemistry | Mice, Inbred C57BL | Cells, Cultured | Tumor Microenvironment | Melanoma - pathology | RNAi Therapeutics - methods | Drug Delivery Systems | Macrophages - metabolism | Animals | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Melanoma - genetics | Melanoma - immunology | RNA, Small Interfering - therapeutic use | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Female | Melanoma - therapy | RNA, Small Interfering - administration & dosage | Macrophages - immunology | Cytokines - immunology | Index Medicus
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4. Full Text IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
by Nold-Petry, Claudia A and Lo, Camden Y and Rudloff, Ina and Elgass, Kirstin D and Li, Suzhao and Gantier, Michael P and Lotz-Havla, Amelie S and Gersting, Søren W and Cho, Steven X and Lao, Jason C and Ellisdon, Andrew M and Rotter, Björn and Azam, Tania and Mangan, Niamh E and Rossello, Fernando J and Whisstock, James C and Bufler, Philip and Garlanda, Cecilia and Mantovani, Alberto and Dinarello, Charles A and Nold, Marcel F
Nature immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 354 - 365
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation - pathology | Interleukin-1 - genetics | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | Receptors, Interleukin-1 - genetics | NF-kappa B - immunology | Receptor Protein-Tyrosine Kinases - immunology | Proto-Oncogene Proteins c-fyn - genetics | Signal Transduction - immunology | TOR Serine-Threonine Kinases - genetics | PTEN Phosphohydrolase - immunology | RNA, Small Interfering - immunology | Receptors, Interleukin-1 - deficiency | Leukocytes, Mononuclear - immunology | c-Mer Tyrosine Kinase | Interleukin-1 - immunology | Interleukin-18 Receptor alpha Subunit - genetics | Proto-Oncogene Proteins - immunology | Proto-Oncogene Proteins c-fyn - immunology | STAT3 Transcription Factor - genetics | Cell Line | PTEN Phosphohydrolase - genetics | Interleukin-18 Receptor alpha Subunit - immunology | Leukocytes, Mononuclear - drug effects | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | RNA-Binding Proteins - immunology | Gene Expression Regulation | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Inflammation - immunology | Immunity, Innate | MAP Kinase Kinase Kinases - immunology | Interleukin-18 Receptor alpha Subunit - antagonists & inhibitors | Leukocytes, Mononuclear - pathology | TOR Serine-Threonine Kinases - immunology | Animals | NF-kappa B - genetics | Receptor Protein-Tyrosine Kinases - genetics | Lipopolysaccharides - pharmacology | Inflammation - genetics | Protein Binding | Mice | STAT3 Transcription Factor - immunology | Receptors, Interleukin-1 - antagonists & inhibitors | Index Medicus
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5. Full Text Activation of the interferon system by short-interfering RNAs
by Holko, Michelle and Silverman, Robert H and Sledz, Carol A and Williams, Bryan R.G and de Veer, Michael J
Nature cell biology, ISSN 1465-7392, 09/2003, Volume 5, Issue 9, pp. 834 - 839
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Interferons - biosynthesis | RNA Interference - immunology | Interferon Inducers - metabolism | Protein-Tyrosine Kinases - metabolism | eIF-2 Kinase - metabolism | Cells, Cultured | RNA, Small Interfering - adverse effects | Eukaryotic Cells - metabolism | Gene Silencing - immunology | Up-Regulation - genetics | Gene Expression Regulation, Viral - genetics | Interferon Inducers - adverse effects | Janus Kinase 1 | Protein-Tyrosine Kinases - genetics | Animals | RNA, Viral - genetics | Up-Regulation - immunology | RNA, Double-Stranded - genetics | RNA, Double-Stranded - immunology | RNA, Viral - immunology | Interferons - genetics | Drosophila melanogaster | RNA, Small Interfering - metabolism | eIF-2 Kinase - genetics | Physiological aspects | Interferon | Research | Index Medicus
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6. Full Text Highly efficacious antiviral protection of plants by small interfering RNAs identified in vitro
by Gago-Zachert, Selma and Schuck, Jana and Weinholdt, Claus and Knoblich, Marie and Pantaleo, Vitantonio and Grosse, Ivo and Gursinsky, Torsten and Behrens, Sven-Erik
Nucleic acids research, ISSN 0305-1048, 09/2019, Volume 47, Issue 17, pp. 9343 - 9357
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | RNA, Small Interfering - genetics | Antiviral Agents - pharmacology | RNA Interference - immunology | Gene Expression Regulation, Plant - immunology | Virus Replication - genetics | Antiviral Agents - immunology | Plant Diseases - immunology | RNA, Small Interfering - pharmacology | Gene Expression Regulation, Plant - genetics | Arabidopsis - genetics | Plant Diseases - virology | RNA, Small Interfering - immunology | Plant Diseases - genetics | Arabidopsis - virology | Index Medicus | RNA and RNA-protein complexes
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7. Full Text Cholesterol modification of p40-specific small interfering RNA enables therapeutic targeting of dendritic cells
by Brück, Jürgen and Pascolo, Steve and Fuchs, Kerstin and Kellerer, Christina and Glocova, Ivana and Geisel, Julia and Dengler, Katja and Yazdi, Amir S and Röcken, Martin and Ghoreschi, Kamran
The Journal of immunology (1950), ISSN 0022-1767, 09/2015, Volume 195, Issue 5, pp. 2216 - 2223
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-12 Subunit p40 - genetics | RNA, Small Interfering - genetics | Dendritic Cells - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Cholesterol - immunology | Interleukin-12 Subunit p40 - blood | Th1 Cells - immunology | Cholesterol - chemistry | Th1 Cells - metabolism | Flow Cytometry | RNA, Small Interfering - immunology | Th17 Cells - metabolism | Gene Expression - immunology | Female | Molecular Structure | Encephalomyelitis, Autoimmune, Experimental - genetics | Interleukin-12 Subunit p40 - immunology | Dendritic Cells - metabolism | Immunization - methods | Treatment Outcome | Mice, Inbred Strains | Reverse Transcriptase Polymerase Chain Reaction | RNAi Therapeutics - methods | Encephalomyelitis, Autoimmune, Experimental - therapy | Animals | Interleukin-10 - genetics | Th17 Cells - immunology | Interleukin-10 - immunology | Index Medicus | Abridged Index Medicus
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8. Full Text Comprehensive transcriptome analyses reveal that potato spindle tuber viroid triggers genome-wide changes in alternative splicing, inducible trans-acting activity of phased secondary small interfering RNAs, and immune responses
by Zheng, Yi and Wang, Ying and Ding, Biao and Fei, Zhangjun
Journal of virology, ISSN 0022-538X, 06/2017, Volume 91, Issue 11
Inducible phasiRNA | Alternative splicing | Noncoding RNA | Immune responses | Viroid | Genome, Viral | RNA, Small Interfering - genetics | Protein Kinases - genetics | Solanum tuberosum - virology | Alternative Splicing | Signal Transduction | Lycopersicon esculentum - virology | Plant Diseases - immunology | Gene Expression Regulation | Plant Leaves - virology | Gene Expression Profiling | Viroids - genetics | Lycopersicon esculentum - physiology | Host-Pathogen Interactions - immunology | Plant Diseases - virology | RNA, Viral - genetics | Hormones - metabolism | MicroRNAs | Mitogen-Activated Protein Kinases - genetics | Lycopersicon esculentum - immunology | Index Medicus
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9. Full Text Blocking the immunosuppressive axis with small interfering RNA targeting interleukin (IL)‐10 receptor enhances dendritic cell‐based vaccine potency
by Kim, J. H and Kang, T. H and Noh, K. H and Bae, H. C and Ahn, Y‐H and Lee, Y‐H and Choi, E. Y and Chun, K‐H and Lee, S‐J and Kim, T. W
Clinical and experimental immunology, ISSN 0009-9104, 08/2011, Volume 165, Issue 2, pp. 180 - 189
immunosuppression | siRNA | IL‐10 receptor | dendritic cell | immunotherapy | Dendritic cell | Immunosuppression | IL-10 receptor | SiRNA | Immunotherapy | Life Sciences & Biomedicine | Immunology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Analytical, structural and metabolic biochemistry | Genes, MHC Class II | Dendritic Cells - immunology | Papillomavirus E7 Proteins - immunology | Th1 Cells - immunology | Lipopolysaccharides | Cancer Vaccines - therapeutic use | Flow Cytometry | Transfection | RNA Interference | Female | CD40 Antigens - genetics | Tumor Cells, Cultured | Dendritic Cells - metabolism | Receptors, Interleukin-10 - immunology | Lymphocyte Activation | Down-Regulation | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Immune Tolerance | Interleukin-12 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cancer Vaccines - immunology | Animals | Interleukin-10 - genetics | Mice | RNA, Small Interfering | CD8-Positive T-Lymphocytes - immunology | Interleukin-10 - immunology | CD40 Antigens - immunology | Receptors, Interleukin-10 - genetics | Medical colleges | Dendritic cells | RNA | Oncology, Experimental | Vaccination | Vaccines | Research | T cells | Interleukins | Health aspects | Papillomavirus infections | Tumors | Cancer | Cytokines | Medical research | Rodents | Translation | CD40 antigen | CD8 antigen | Therapeutic applications | Paracrine signalling | Interleukin 12 | Inflammation | Lymphocytes T | Cell surface | Major histocompatibility complex | Interleukin 10 | Autocrine signalling | Index Medicus | Translational Studies
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