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Biochemistry, ISSN 0006-2960, 08/2017, Volume 56, Issue 31, pp. 4029 - 4038
Journal Article
Biochemistry, ISSN 0006-2960, 01/2001, Volume 40, Issue 3, pp. 603 - 608
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 128 - 132
Folates enable the activation and transfer of one-carbon units for the biosynthesis of purines, thymidine and methionine(1-3). Antifolates are important... 
CHAIN | HYPERTROPHIC CARDIOMYOPATHY | SERINE HYDROXYMETHYLTRANSFERASE | METABOLISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DEFECT | LACTIC-ACIDOSIS | MUTATIONS | IDENTIFICATION | ANTICODON WOBBLE NUCLEOTIDE | Mitochondria - enzymology | Electron Transport | Protein Biosynthesis | Humans | Ribosomes - metabolism | Sarcosine - metabolism | Multifunctional Enzymes - metabolism | Thymine Nucleotides - biosynthesis | Oxidative Phosphorylation - drug effects | Glycine Hydroxymethyltransferase - deficiency | HEK293 Cells | RNA, Transfer - genetics | Codon - genetics | RNA, Transfer - chemistry | Leucine - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Biocatalysis | RNA, Transfer - metabolism | HCT116 Cells | Mitochondria - metabolism | Mitochondria - drug effects | Glycine Hydroxymethyltransferase - metabolism | Guanosine - metabolism | Tetrahydrofolates - metabolism | Lysine - genetics | Carrier Proteins - metabolism | Methylation - drug effects | Folic Acid - metabolism | Aminohydrolases - metabolism | Folic Acid Antagonists - pharmacology | GTP-Binding Proteins - metabolism | Mitochondria | Physiological aspects | Genetic aspects | Methylation | Observations | Genetic translation | Folic acid | Transfer RNA | Phosphorylation | Inborn errors of metabolism | Peptides | Serine | Biosynthesis | Mitochondrial DNA | Thymidine | Catalytic activity | Leucine | Cytosol | Experiments | Anticancer properties | Proteins | Purines | Antitumor agents | Metabolites | Lymphocytes | Vitamin B | Catalysis | Enzymes | Translation | tRNA Ala | tRNA | Methionine | Metabolism | Carbon | Immunosuppression | Oxidative phosphorylation | Lysine | Proteomics | Electron transport | Respiration | Codons | Cancer
Journal Article
FEMS Microbiology Reviews, ISSN 0168-6445, 03/2008, Volume 32, Issue 2, pp. 386 - 408
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 08/2017, Volume 292, Issue 32, pp. 13258 - 13270
The beta-secretase (BACE1) initiates processing of the amyloid precursor protein (APP) into A beta peptides, which have been implicated as central players in... 
BACE1 | CLEAVING ENZYME | DOMAIN | WILSON-DISEASE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEQUENCE | AMYLOID-PRECURSOR-PROTEIN | MICE | MODEL | INFLUENZA-VIRUS HEMAGGLUTININ | Amyloid Precursor Protein Secretases - genetics | Humans | Protein Multimerization | Bacterial Proteins - chemistry | Alanine - chemistry | Green Fluorescent Proteins - genetics | Aspartic Acid Endopeptidases - genetics | Recombinant Fusion Proteins - metabolism | Biological Transport | RNA Interference | Copper - metabolism | HEK293 Cells | Fluorescence Resonance Energy Transfer | Luminescent Proteins - chemistry | Protein Interaction Domains and Motifs | Green Fluorescent Proteins - chemistry | Aspartic Acid Endopeptidases - chemistry | Green Fluorescent Proteins - metabolism | Mutagenesis, Site-Directed | Aspartic Acid Endopeptidases - antagonists & inhibitors | Bacterial Proteins - genetics | Models, Molecular | Cysteine - chemistry | Recombinant Fusion Proteins - chemistry | Amyloid Precursor Protein Secretases - chemistry | Protein Folding | Point Mutation | Amyloid Precursor Protein Secretases - metabolism | Aspartic Acid Endopeptidases - metabolism | Bacterial Proteins - metabolism | Cytosol - metabolism | Luminescent Proteins - genetics | Protein Conformation | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Microscopy, Fluorescence | Amino Acid Substitution | Luminescent Proteins - metabolism | single-molecule biophysics | stoichiometry | protein cross-linking | beta-secretase 1 (BACE1) | copper transport | Cell Biology
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 1986, Volume 163, Issue 5, pp. 1281 - 1291
The sera of six patients with autoimmune disease, predominantly myositis with pulmonary fibrosis, contain antibodies of the PL-12 specificity. These... 
Amino Acyl-tRNA Synthetases - immunology | Antibody Specificity | Alanine | Alanine-tRNA Ligase - antagonists & inhibitors | Humans | Middle Aged | Autoimmune Diseases - immunology | Male | Myositis - immunology | Autoantibodies - immunology | Alanine-tRNA Ligase - immunology | Adult | Female | RNA, Transfer - immunology
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2007, Volume 37, Issue 2, pp. 222 - 231
Endothelial cell (EC) barrier dysfunction (i.e., increased vascular permeability) is observed in inflammatory states, tumor angiogenesis, atherosclerosis, and... 
Methylnaltrexone | S1P3 receptor | Vascular permeability | EC barrier regulation | mu opioid receptor | CELLS | ENDOTHELIAL BARRIER DYSFUNCTION | MU OPIATE RECEPTOR | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTOXIN | ACUTE LUNG INJURY | methylnaltrexone | ACTIVATED RECEPTORS | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | RESPIRATORY SYSTEM | ENHANCEMENT | LIPOPOLYSACCHARIDE | vascular permeability | Naltrexone - analogs & derivatives | RNA, Small Interfering - genetics | Humans | Transcriptional Activation | Capillary Permeability - drug effects | Electrophysiology | Molecular Sequence Data | Male | rhoA GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | rhoA GTP-Binding Protein - genetics | Naltrexone - pharmacology | Enkephalin, Ala-MePhe-Gly- - metabolism | rho-Associated Kinases | Receptors, Lysosphingolipid - genetics | Receptors, Lysosphingolipid - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Naloxone - metabolism | Endothelial Cells - metabolism | Receptors, Opioid, mu - metabolism | Mice, Inbred C57BL | Cells, Cultured | Morphine - metabolism | Protein-Serine-Threonine Kinases - genetics | Receptors, Opioid, mu - antagonists & inhibitors | Animals | Endothelial Cells - cytology | Narcotic Antagonists - pharmacology | Mice | Analgesics, Opioid - metabolism | Receptors, Opioid, mu - genetics | Thrombin - metabolism | Endothelial Cells - drug effects | Quaternary Ammonium Compounds - pharmacology | RNA, Small Interfering - metabolism
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 05/2014, Volume 181, Issue 1, pp. 32 - 39
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 11/2008, Volume 33, Issue 12, pp. 2957 - 2968
Journal Article