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by Gordon, David E and Jang, Gwendolyn M and Bouhaddou, Mehdi and Xu, Jiewei and White, Kris M and O’Meara, Matthew J and Rezelj, Veronica V and Swaney, Danielle L and Tummino, Tia A and Foussard, Helene and Batra, Jyoti and Haas, Kelsey and Modak, Maya and Kim, Minkyu and Braberg, Hannes and Fabius, Jacqueline M and Eckhardt, Manon and Soucheray, Margaret and Cakir, Merve and McGregor, Michael J and Li, Qiongyu and Vallet, Thomas and Mac Kain, Alice and Miorin, Lisa and Moreno, Elena and Zhou, Yuan and Peng, Shiming and Shi, Ying and Zhang, Ziyang and Shen, Wenqi and Melnyk, James E and Chorba, John S and Lou, Kevin and Dai, Shizhong A and Barrio-Hernandez, Inigo and Lyu, Jiankun and Mathy, Christopher J. P and Perica, Tina and Pilla, Kala Bharath and Ganesan, Sai J and Saltzberg, Daniel J and Rakesh, Ramachandran and Liu, Xi and Rosenthal, Sara B and Calviello, Lorenzo and Lin, Yizhu and Huang, Xi-Ping and Liu, YongFeng and Bohn, Markus and Safari, Maliheh and Ugur, Fatima S and Koh, Cassandra and Savar, Nastaran Sadat and Tran, Quang Dinh and Fletcher, Sabrina J and O’Neal, Michael C and Chang, Jason C. J and Broadhurst, David J and Klippsten, Saker and Sharp, Phillip P and Wenzell, Nicole A and Kuzuoglu-Ozturk, Duygu and Wang, Hao-Yuan and Trenker, Raphael and Young, Janet M and Cavero, Devin A and Hiatt, Joseph and Roth, Theodore L and Rathore, Ujjwal and Subramanian, Advait and Noack, Julia and Hubert, Mathieu and Stroud, Robert M and Frankel, Alan D and Rosenberg, Oren S and Verba, Kliment A and Agard, David A and Ott, Melanie and Emerman, Michael and Jura, Natalia and von Zastrow, Mark and Verdin, Eric and Ashworth, Alan and Schwartz, Olivier and d’Enfert, Christophe and Mukherjee, Shaeri and Jacobson, Matt and Malik, Harmit S and Craik, Charles S and Floor, Stephen N and Fraser, James S and Gross, John D and Roth, Bryan L and Ruggero, Davide and Taunton, Jack and Beltrao, Pedro and García-Sastre, Adolfo and Shokat, Kevan M and Shoichet, Brian K and Krogan, Nevan J
Nature (London), ISSN 0028-0836, 07/2020, Volume 583, Issue 7816, pp. 459 - 468
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Betacoronavirus - pathogenicity | Pandemics | Coronavirus Infections - drug therapy | Humans | Pneumonia, Viral - drug therapy | Host-Pathogen Interactions - drug effects | Molecular Targeted Therapy | Viral Proteins - metabolism | Protein Interaction Maps | COVID-19 | Pneumonia, Viral - metabolism | SARS-CoV-2 | Antiviral Agents - classification | Coronavirus Infections - metabolism | Mass Spectrometry | Cloning, Molecular | HEK293 Cells | Protein Domains | Drug Evaluation, Preclinical | Receptors, sigma - metabolism | Vero Cells | Antiviral Agents - pharmacology | Chlorocebus aethiops | Betacoronavirus - drug effects | Viral Proteins - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Drug Repositioning | Betacoronavirus - metabolism | Immunity, Innate | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Protein Interaction Mapping | Animals | Coronavirus Infections - virology | Protein Binding | Protein Biosynthesis - drug effects | Betacoronavirus - genetics | Pneumonia, Viral - virology | Protein research | Drug targeting | Genetic aspects | Coronaviruses | Research | Health aspects | Methods | Interactomes | Drugs | Regulators | Laboratories | Protein purification | Viral diseases | Clinical trials | Infections | Genomes | mRNA | Vaccines | Middle East respiratory syndrome | Proteins | Antiviral activity | Antiviral agents | Enzymes | Severe acute respiratory syndrome | Cloning | Mass spectroscopy | RNA polymerase | Gene expression | Severe acute respiratory syndrome coronavirus 2 | Respiratory diseases | Fatalities | Scientific imaging | Protein interaction | Mass spectrometry | Index Medicus
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