X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (2020) 2020
index medicus (1831) 1831
animals (1499) 1499
rna-binding proteins - metabolism (1493) 1493
rna-binding proteins - genetics (1054) 1054
biochemistry & molecular biology (901) 901
mice (785) 785
cell biology (674) 674
proteins (623) 623
rna-binding proteins - antagonists & inhibitors (604) 604
cell line, tumor (538) 538
expression (534) 534
protein binding (460) 460
rna, messenger - metabolism (447) 447
rna (441) 441
female (434) 434
male (420) 420
gene expression (418) 418
cell line (405) 405
oncology (385) 385
apoptosis (379) 379
signal transduction (362) 362
phosphorylation (361) 361
research (358) 358
cancer (352) 352
messenger-rna (347) 347
rna-binding protein (341) 341
rna-binding proteins (328) 328
molecular sequence data (313) 313
rna, messenger - genetics (309) 309
gene-expression (306) 306
rna interference (288) 288
cells, cultured (275) 275
hela cells (268) 268
research article (257) 257
rats (253) 253
analysis (250) 250
multidisciplinary sciences (248) 248
base sequence (244) 244
ribonucleic acid--rna (239) 239
cell proliferation (233) 233
amino acid sequence (229) 229
mutation (228) 228
protein (225) 225
binding sites (224) 224
rna, small interfering - genetics (221) 221
transcription (215) 215
biology (213) 213
genetic aspects (213) 213
rna-binding proteins - physiology (213) 213
activation (206) 206
cells (205) 205
nuclear proteins - metabolism (204) 204
rna-binding proteins - chemistry (204) 204
neurosciences (203) 203
identification (202) 202
viruses (202) 202
gene expression regulation (201) 201
physiological aspects (194) 194
transfection (193) 193
gene expression regulation, neoplastic (187) 187
virology (185) 185
micrornas - genetics (178) 178
kinases (177) 177
down-regulation (175) 175
transcription factors - metabolism (174) 174
micrornas - metabolism (172) 172
health aspects (171) 171
rna, small interfering - metabolism (171) 171
phosphoproteins - metabolism (170) 170
dna-binding proteins - metabolism (168) 168
gene (167) 167
in-vivo (167) 167
translation (163) 163
genes (161) 161
genetics & heredity (159) 159
messenger rna (159) 159
binding (157) 157
apoptosis - drug effects (156) 156
hek293 cells (151) 151
inhibition (151) 151
molecular biology (150) 150
medicine (149) 149
enzyme inhibitors - pharmacology (147) 147
protein biosynthesis (146) 146
science (145) 145
transcription, genetic (145) 145
blotting, western (140) 140
biochemistry (132) 132
cell cycle (132) 132
gene knockdown techniques (132) 132
reverse transcriptase polymerase chain reaction (132) 132
tumors (132) 132
dna-binding proteins - genetics (131) 131
growth (131) 131
life sciences (128) 128
alternative splicing (127) 127
microrna (127) 127
cell nucleus - metabolism (126) 126
mice, inbred c57bl (126) 126
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2904) 2904
Chinese (19) 19
Japanese (17) 17
French (4) 4
German (3) 3
Russian (2) 2
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Death and Differentiation, ISSN 1350-9047, 01/2014, Volume 21, Issue 1, pp. 79 - 91
The immunogenic demise of cancer cells can be induced by various chemotherapeutics, such as anthracyclines and oxaliplatin, and provokes an immune response... 
quinacrine | apoptosis | U2OS cells | caspases | endoplasmic reticulum stress | Beclin 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | AUTOPHAGY | CLEAVAGE | CHEMOTHERAPY | CELL BIOLOGY | CALRETICULIN EXPOSURE | PANNEXIN 1 | ASSAYS | FIND-ME SIGNAL | Connexins - antagonists & inhibitors | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cell Death - immunology | rho-Associated Kinases - antagonists & inhibitors | Antineoplastic Agents - toxicity | DNA-Binding Proteins - metabolism | Lysosomes - metabolism | Lysosomal-Associated Membrane Protein 1 - genetics | Myosin Type II - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Adenosine Triphosphate - metabolism | HMGB1 Protein - metabolism | Cell Membrane - metabolism | Cell Death - drug effects | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Connexins - genetics | rho-Associated Kinases - genetics | Lysosomal-Associated Membrane Protein 1 - antagonists & inhibitors | Microtubule-Associated Proteins - antagonists & inhibitors | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Animals | Autophagy-Related Protein 5 | Cell Line, Tumor | Lysosomal-Associated Membrane Protein 1 - metabolism | Mice | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Original Paper
Journal Article
Cell Reports, ISSN 2211-1247, 01/2016, Volume 14, Issue 3, pp. 598 - 610
.... Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA... 
TARGET | CHROMOSOME-TRANSLOCATION | DNA-BINDING | SOLID TUMORS | GENE | EWS/FLI-1 FUSION | PLADIENOLIDE | PHASE-I | CANCER | FAMILY | CELL BIOLOGY | RNA-Binding Proteins - genetics | Oncogene Proteins, Fusion - metabolism | Exons | Humans | Gene Expression Regulation, Neoplastic | Sarcoma, Ewing - pathology | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA Splicing | Ribonucleoprotein, U2 Small Nuclear - metabolism | RNA-Binding Protein EWS - antagonists & inhibitors | RNA Interference | Proto-Oncogene Protein c-fli-1 - metabolism | Base Sequence | Calmodulin-Binding Proteins - antagonists & inhibitors | Ribonucleoprotein, U2 Small Nuclear - genetics | RNA Precursors - metabolism | Microfilament Proteins - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - antagonists & inhibitors | Binding Sites | Microfilament Proteins - genetics | RNA-Binding Proteins - antagonists & inhibitors | Calmodulin-Binding Proteins - genetics | Proto-Oncogene Protein c-fli-1 - genetics | Cell Survival | RNA-Binding Protein EWS - genetics | RNA Splicing Factors | Transcription Factors - antagonists & inhibitors | Calmodulin-Binding Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | RNA-Binding Protein EWS - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - genetics | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - metabolism | Transcription Factors - metabolism | Proto-Oncogene Protein c-fli-1 - antagonists & inhibitors | Microfilament Proteins - antagonists & inhibitors | Oncogene Proteins, Fusion - genetics | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Cell Line, Tumor | Ribonucleoprotein, U2 Small Nuclear - antagonists & inhibitors | Oncogene Proteins, Fusion - antagonists & inhibitors | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2016, Volume 59, Issue 4, pp. 1271 - 1298
Bromodomains, small protein modules that recognize acetylated lysine on histones, play a significant role in the epigenome, where they function as “readers... 
CHEMISTRY, MEDICINAL | SWI/SNF COMPLEXES | SMALL-MOLECULE INHIBITORS | PROSTATE-CANCER | SELECTIVE INHIBITORS | GENE-EXPRESSION | CHEMICAL PROBE | TUMOR-SUPPRESSOR | BET INHIBITORS | HISTONE ACETYLTRANSFERASE | PHD FINGER | Small Molecule Libraries - pharmacology | Antigens, Nuclear - metabolism | Humans | Drug Discovery - methods | CREB-Binding Protein - antagonists & inhibitors | Chromosomal Proteins, Non-Histone - antagonists & inhibitors | DNA-Binding Proteins - metabolism | CREB-Binding Protein - metabolism | Protein Processing, Post-Translational - drug effects | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Lysine - metabolism | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | ATPases Associated with Diverse Cellular Activities | DNA-Binding Proteins - antagonists & inhibitors | Chromosomal Proteins, Non-Histone - metabolism | Carrier Proteins - antagonists & inhibitors | Adenosine Triphosphatases - metabolism | Models, Molecular | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Adenosine Triphosphatases - antagonists & inhibitors | DNA Helicases - metabolism | Small Molecule Libraries - chemistry | Acetylation - drug effects | Animals | Carrier Proteins - metabolism | Nuclear Proteins - antagonists & inhibitors | DNA Helicases - antagonists & inhibitors | Histones - metabolism | Adaptor Proteins, Signal Transducing - metabolism | RNA-Binding Proteins - metabolism
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2017, Volume 23, Issue 9, pp. 1055 - 1062
Bromodomain and extraterminal domain (BET) protein inhibitors are emerging as promising anticancer therapies... 
SELECTIVE-INHIBITION | TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | ANDROGEN RECEPTOR | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | ENHANCERS | CELL BIOLOGY | RNA-SEQ | BROMODOMAIN INHIBITION | MUTATIONS | BRD4 | Prostatic Neoplasms - metabolism | Immunoprecipitation | TOR Serine-Threonine Kinases - metabolism | Humans | Drug Resistance, Neoplasm | Male | Gene Expression Profiling | Molecular Targeted Therapy | Mechanistic Target of Rapamycin Complex 1 | Transcription Factors - drug effects | Multiprotein Complexes - metabolism | Prostatic Neoplasms - genetics | Proteasome Endopeptidase Complex - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Nuclear Proteins - drug effects | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | TOR Serine-Threonine Kinases - drug effects | Multiprotein Complexes - drug effects | Prostatic Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Triazoles - therapeutic use | Cell Survival | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Azepines - therapeutic use | RNA-Binding Proteins - drug effects | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Nuclear Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Mutation | RNA-Binding Proteins - metabolism | rac1 GTP-Binding Protein - metabolism | Proto-Oncogene Proteins c-akt - drug effects | rac1 GTP-Binding Protein - genetics | Gene mutations | Physiological aspects | Genetic aspects | Research | Drug resistance | Drug therapy | Prostate cancer | Ubiquitin | Inhibitor drugs | Stabilization | AKT protein | Activation | Biosynthesis | Degradation | Proteins | Ubiquitination | Transcription activation | Ubiquitin-protein ligase | Binding | Rac1 protein | Tumor cell lines | Gene expression | Cholesterol | Mutants | Inhibitors | Proteasomes | Biomarkers | Bet protein | Prostate | Cancer | Guanosinetriphosphatase
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7391, pp. 598 - 602
...). Whereas several proteins are known to regulate chromatin marks associated with the distinct epigenetic states of cells before and after reprogramming(2,3... 
CELLS | LEUKEMIA | PRC2 | HISTONE METHYLATION | MULTIDISCIPLINARY SCIENCES | PLURIPOTENT | Chromatin - metabolism | Homeodomain Proteins - metabolism | Humans | Methyltransferases - metabolism | Methyltransferases - genetics | Methyltransferases - biosynthesis | YY1 Transcription Factor - metabolism | Repressor Proteins - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Kruppel-Like Transcription Factors - metabolism | YY1 Transcription Factor - antagonists & inhibitors | Induced Pluripotent Stem Cells - cytology | Cellular Reprogramming - genetics | Repressor Proteins - metabolism | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Nanog Homeobox Protein | Transcription Factors - antagonists & inhibitors | DNA Methylation - genetics | Polycomb-Group Proteins | Proto-Oncogene Proteins c-myc - metabolism | Enhancer of Zeste Homolog 2 Protein | Transcription Factors - metabolism | Polycomb Repressive Complex 2 | Methyltransferases - antagonists & inhibitors | Fibroblasts - cytology | RNA, Small Interfering | Histones - metabolism | Methylation | Chromatin - genetics | RNA-Binding Proteins - metabolism | Physiological aspects | Chromatin | Genetic aspects | Research | Methyltransferases | Embryonic stem cells | Enzymes | Efficiency | Stem cells | Epigenetics | Kinases | Gene expression | Apoptosis
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 3, pp. 520 - 533
The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its co-factor Mtr4p/hMTR4, which links to RNA-binding protein adaptors... 
RNA exosome | PAXT connection | nuclear RNA decay | poly(A) tail | NEXT complex | COMPLEX | MESSENGER-RNA | CRYPTIC UNSTABLE TRANSCRIPTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOLECULAR ARCHITECTURE | POLY(A)-BINDING PROTEIN | POLYMERASE | 3'-END MATURATION | QUALITY CONTROL | DEGRADATION | POLY(A) TAIL LENGTH | CELL BIOLOGY | RNA Helicases - metabolism | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | RNA, Messenger - metabolism | Cell Nucleus - metabolism | HEK293 Cells | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Helicases - genetics | Exosome Multienzyme Ribonuclease Complex - genetics | Nuclear Proteins - genetics | Poly(A)-Binding Protein I - genetics | Binding Sites | RNA-Binding Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Carrier Proteins - antagonists & inhibitors | Poly(A)-Binding Protein I - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Poly A - genetics | Transcription Factors - genetics | RNA Stability - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Poly A - metabolism | Carrier Proteins - metabolism | Cell Nucleus - genetics | Nuclear Proteins - antagonists & inhibitors | Poly(A)-Binding Protein I - antagonists & inhibitors | Protein Binding | HeLa Cells | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Zinc compounds | RNA | Molecular biology | Protein binding
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 1, pp. 268 - 277.e18
Background & Aims There has not been a broad analysis of the combined effects of altered activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma... 
Gastroenterology and Hepatology | miRNA−mRNA Interaction | Tumorigenesis | Pancreatic Cancer | Oncogene | miRNA-mRNA Interaction | SURVIVAL | TRANSFORMATION | POSTTRANSCRIPTIONAL REGULATION | CANCER CELLS | DUCTAL ADENOCARCINOMA | NEDD4L | IN-VITRO | TARGETS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | LASER MICRODISSECTION | Cell Proliferation | Prognosis | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Ubiquitin-Protein Ligases - antagonists & inhibitors | Gene Expression Profiling | Ubiquitin-Protein Ligases - physiology | Carcinoma, Pancreatic Ductal - genetics | Endosomal Sorting Complexes Required for Transport - antagonists & inhibitors | Genes, Tumor Suppressor - physiology | Nedd4 Ubiquitin Protein Ligases | Gene Expression Regulation, Neoplastic - genetics | RNA-Binding Proteins - antagonists & inhibitors | Immediate-Early Proteins - physiology | RNA-Binding Proteins - physiology | RNA, Messenger - genetics | Pancreatic Neoplasms - genetics | Disease Progression | Tumor Suppressor Proteins - physiology | Animals | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Apoptosis Regulatory Proteins - physiology | Mice | MicroRNAs - genetics | MicroRNAs - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Immediate-Early Proteins - antagonists & inhibitors | Care and treatment | MicroRNA | Pancreatic cancer | Analysis | Genes | Development and progression | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72967
BET family proteins are epigenetic regulators known to control expression of genes involved in cell growth and oncogenesis... 
APOPTOSIS | THERAPEUTIC STRATEGY | MULTIDISCIPLINARY SCIENCES | GROWTH | N-MYC | C-MYC | GENE-EXPRESSION | BROMODOMAIN INHIBITION | TARGETS | CELL-LINES | IDENTIFICATION | Oncogene Proteins - genetics | Transcription Factors - chemistry | Apoptosis - drug effects | Humans | Molecular Conformation | Apoptosis - genetics | Gene Expression Profiling | Gene Regulatory Networks | Antineoplastic Agents - toxicity | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Tumor Burden - genetics | Antineoplastic Agents - pharmacology | N-Myc Proto-Oncogene Protein | Gene Expression Regulation, Neoplastic - drug effects | Nuclear Proteins - genetics | Neuroblastoma - pathology | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | RNA-Binding Proteins - antagonists & inhibitors | Benzodiazepines - pharmacology | Neuroblastoma - genetics | RNA-Binding Proteins - chemistry | Gene Silencing | Models, Molecular | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Antineoplastic Agents - chemistry | Nuclear Proteins - chemistry | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Animals | Benzodiazepines - toxicity | Signal Transduction - drug effects | Tumor Burden - drug effects | Neuroblastoma - drug therapy | Nuclear Proteins - antagonists & inhibitors | Benzodiazepines - chemistry | Protein Binding | Cell Proliferation - drug effects | Mice | Neuroblastoma - metabolism | Protein-Serine-Threonine Kinases - chemistry | Kinetics | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA-Binding Proteins - metabolism | Cluster Analysis | Proteins | Epigenetic inheritance | Care and treatment | Analysis | Genes | Neuroblastoma | Gene expression | Cancer | Biotechnology | Regulators | Animal models | Transcription factors | Toxicity | Copy number | Leukemia | Gene regulation | Cytotoxicity | Myc protein | Cell growth | Pathways | Cell cycle | Xenografts | Tumorigenesis | Inhibition | Oral administration | Signaling | Sensitivity | Gene amplification | Chemotherapy | Inhibitors | Epigenetics | Lymphomas | Solid tumors | Apoptosis | Tumors
Journal Article
Nature Communications, ISSN 2041-1723, 12/2016, Volume 7, Issue 1, p. 13875
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 33, pp. 13745 - 13757
Messenger RNA alternative splicing (AS) regulates the expression of a variety of genes involved in both physiological and pathological processes. AS of the... 
TARGET | PREDICTS | MESSENGER-RNA | VARIANTS | SPECIFICITY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SURVIVIN-DELTA-EX3 | CELL | EXPRESSION | RNA-Binding Proteins - genetics | Alternative Splicing | Exons | Inhibitor of Apoptosis Proteins - genetics | Humans | Neoplasm Proteins - antagonists & inhibitors | Transplantation, Heterologous | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | RNA, Neoplasm - metabolism | DNA-Binding Proteins - metabolism | Protein Isoforms - metabolism | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Gene Deletion | Clone Cells | Inhibitor of Apoptosis Proteins - metabolism | Neoplasm Proteins - genetics | RNA-Binding Proteins - antagonists & inhibitors | RNA, Neoplasm - chemistry | Recombinant Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Mutagenesis, Site-Directed | Response Elements | Recombinant Proteins - chemistry | Zebrafish | Tumor Burden | DNA-Binding Proteins - genetics | Point Mutation | Animals | Adaptor Proteins, Signal Transducing - genetics | CRISPR-Cas Systems | Embryo, Nonmammalian | RNA, Messenger - chemistry | Neoplasm Transplantation - pathology | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - antagonists & inhibitors | RNA-Binding Proteins - metabolism | Protein Isoforms - genetics | survivin | KHDRBS1 | alternative splicing | survivin DEx3 | gene regulation | cancer | cancer biology | Sam68 | Cell Biology
Journal Article
12.