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Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6079, pp. 341 - 344
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2016, Volume 62, Issue 2, pp. 295 - 306
(St) type III-A CRISPR-Cas system restricts MS2 RNA phage and cuts RNA in vitro. However, the CRISPR array spacers match DNA phages, raising the question: does... 
SYSTEM | DUAL-RNA | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TRANSCRIPTION | GUIDED SURVEILLANCE COMPLEX | EFFECTOR COMPLEX | INTERFERENCE | CLEAVAGE | CMR COMPLEX | CELL BIOLOGY | RNA, Messenger - immunology | DNA, Bacterial - metabolism | Streptococcus thermophilus - immunology | DNA, Bacterial - immunology | RNA, Messenger - metabolism | Streptococcus thermophilus - virology | DNA, Single-Stranded - genetics | Escherichia coli - virology | RNA, Viral - genetics | Streptococcus thermophilus - metabolism | Time Factors | RNA-Directed DNA Polymerase - genetics | RNA, Viral - metabolism | Streptococcus thermophilus - genetics | Nucleic Acid Conformation | CRISPR-Associated Proteins - immunology | CRISPR-Cas Systems - immunology | RNA-Directed DNA Polymerase - metabolism | CRISPR-Associated Proteins - genetics | DNA, Single-Stranded - metabolism | RNA, Messenger - genetics | DNA, Viral - metabolism | Escherichia coli - immunology | Models, Molecular | RNA Cleavage | RNA Stability | Host-Pathogen Interactions | DNA, Single-Stranded - immunology | DNA, Viral - immunology | DNA, Bacterial - genetics | Escherichia coli - genetics | CRISPR-Associated Proteins - metabolism | Protein Conformation | RNA, Viral - immunology | Mutation | DNA, Viral - genetics | DNA | Messenger RNA | Ribonuclease
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 20, pp. 8290 - 8295
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 09/2017, Volume 45, Issue 15, pp. 9046 - 9058
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0128401
Hepatitis B virus (HBV) replication and persistence are sustained by a nuclear episome, the covalently closed circular (CCC) DNA, which serves as the... 
CLOSED CIRCULAR DNA | CELLS | IN-VITRO | REPLICATION | VIRAL-DNA | TDP2 | MULTIDISCIPLINARY SCIENCES | HEPADNAVIRUS REVERSE-TRANSCRIPTASE | POLYMERASE | ENVELOPE PROTEINS | COVALENT COMPLEXES | Up-Regulation | Hepatitis B - metabolism | Hepatitis B - genetics | Humans | DNA, Circular - genetics | Viral Proteins - metabolism | Gene Knockdown Techniques | Hepatitis Virus, Duck - metabolism | Hepatitis B Virus, Duck - genetics | RNA-Directed DNA Polymerase - genetics | Nuclear Proteins - genetics | Genome, Viral | Hepatitis B Virus, Duck - physiology | RNA-Directed DNA Polymerase - metabolism | DNA, Viral - metabolism | Viral Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - genetics | Gene Knockout Techniques | DNA, Circular - metabolism | Hepatitis B virus - physiology | Hep G2 Cells | Transcription Factors - metabolism | Virus Replication | Hepatitis B virus - genetics | DNA, Viral - genetics | Hepatitis Virus, Duck - genetics | Antiviral agents | Genomics | DNA | DNA polymerases | Hepatitis B virus | Health aspects | Hepatitis B | RNA-directed DNA polymerase | Transcription | Chronic infection | Viruses | Genomes | Infections | Hepatoma | Circular DNA | Aquatic birds | Proteins | Hepatitis | Immunology | Deoxyribonucleic acid--DNA | Phosphodiesterase | CRISPR | DNA topoisomerase (ATP-hydrolysing) | Nucleocapsids | Medicine | Amplification | Progeny | Covalence | Replication | Protein expression | Intracellular | Molecular biology | Cancer | Deoxyribonucleic acid
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2017, Volume 487, Issue 1, pp. 128 - 133
Journal Article
Enzyme and Microbial Technology, ISSN 0141-0229, 01/2017, Volume 96, pp. 111 - 120
Journal Article
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 08/2011, Volume 3, Issue 8, pp. 1 - 19
Journal Article
DNA Repair, ISSN 1568-7864, 08/2016, Volume 44, pp. 6 - 16
DNA double-strand breaks (DSBs) are dangerous lesions that if not properly repaired can lead to genomic change or cell death. Organisms have developed several... 
HO endonuclease | I-SceI endonuclease | Homologous recombination | Gene editing | CRISPR-Cas9 | Double-strand break repair | Nonhomologous end-joining | Homology-directed repair | I-SCEI | ZINC-FINGER NUCLEASES | SACCHAROMYCES-CEREVISIAE | MAMMALIAN-CELLS | CHROMOSOMAL TRANSLOCATION FORMATION | DNA END RESECTION | INDUCED REPLICATION | EMBRYONIC STEM-CELLS | GENETICS & HEREDITY | RNA-GUIDED ENDONUCLEASE | TOXICOLOGY | Endonucleases - genetics | Humans | Endonucleases - metabolism | DNA Breaks, Double-Stranded | Deoxyribonucleases, Type II Site-Specific - genetics | DNA End-Joining Repair | DNA Mismatch Repair | Clustered Regularly Interspaced Short Palindromic Repeats | Endodeoxyribonucleases - metabolism | RNA-Directed DNA Polymerase - genetics | Recombinational DNA Repair | RNA-Directed DNA Polymerase - metabolism | Transcription Activator-Like Effector Nucleases - metabolism | Bacterial Proteins - genetics | DNA - metabolism | Saccharomyces cerevisiae Proteins - genetics | Transcription Activator-Like Effector Nucleases - genetics | DNA - genetics | Deoxyribonucleases, Type II Site-Specific - metabolism | Endodeoxyribonucleases - genetics | CRISPR-Cas Systems | Saccharomyces cerevisiae Proteins - metabolism | Bacterial Proteins - metabolism | Zinc Fingers - genetics | Gene Editing - methods | Democratization | Genetic research | RNA | Cell death | Genes | Biotechnology | Nucleases | Anopheles | Developmental biology | homologous recombination | nonhomologous end-joining | homology-directed repair | gene editing
Journal Article