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Molecular Cell, ISSN 1097-2765, 07/2010, Volume 39, Issue 2, pp. 282 - 291
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 06/2006, Volume 125, Issue 5, pp. 873 - 886
In the fission yeast the RNA-Induced Transcriptional Silencing (RITS) complex has been proposed to target the chromosome via siRNA-dependent base-pairing... 
H3 LYSINE-9 METHYLATION | DOUBLE-STRANDED-RNA | FISSION YEAST | EPIGENETIC CONTROL | HISTONE H3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERFERENCE | MECHANISMS | CHROMOSOME SEGREGATION | POLYMERASE-II | SCHIZOSACCHAROMYCES-POMBE | CELL BIOLOGY | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Exoribonucleases - genetics | Methyltransferases - metabolism | RNA-Induced Silencing Complex - genetics | Methyltransferases - genetics | Schizosaccharomyces - genetics | DNA Methylation | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Gene Expression Regulation, Fungal - genetics | RNA Interference - physiology | Sirtuins - genetics | Schizosaccharomyces pombe Proteins - genetics | Chromosomal Proteins, Non-Histone - metabolism | Cell Cycle Proteins - metabolism | RNA Precursors - genetics | Chromosomal Proteins, Non-Histone - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Heterochromatin - genetics | Histones - metabolism | Sirtuins - metabolism | Exoribonucleases - metabolism | Regulatory Elements, Transcriptional - genetics | Histones | Genetic research | Gene silencing | Research | Chromatin | Genetic engineering | RNA | Methylation | Lysine | Analysis | Index Medicus | Sirtuins | Gene Expression Regulation, Fungal | RNA Precursors | Exoribonucleases | Schizosaccharomyces pombe Proteins | Chromosomal Proteins, Non-Histone | RNA-Binding Proteins | Life Sciences | Heterochromatin | Methyltransferases | RNA Interference | Regulatory Elements, Transcriptional | Genetics | RNA, Small Interfering | Cell Cycle Proteins | RNA-Induced Silencing Complex | Schizosaccharomyces | Carrier Proteins
Journal Article
Genes and Development, ISSN 0890-9369, 11/2006, Volume 20, Issue 21, pp. 2985 - 2995
Most organisms have evolved defense mechanisms to protect themselves from viruses and other pathogens. Arthropods lack the protein-based adaptive immune... 
Antiviral defense | Cricket paralysis virus | dsRNA-binding domain | RNAi suppressor | Drosophila C virus | VIRAL SUPPRESSOR | DEFENSE | DOUBLE-STRANDED-RNA | BINDING MOTIF | PROTEIN | Cricket Paralysis virus | RECOGNITION | DEVELOPMENTAL BIOLOGY | DISTINCT ROLES | CELL BIOLOGY | INTERFERING RNA | ANIMAL VIRUS | GENETICS & HEREDITY | INFECTION | antiviral defense | RNA-Induced Silencing Complex - physiology | Drosophila melanogaster - immunology | RNA-Induced Silencing Complex - genetics | Gene Silencing | Viral Proteins - genetics | Viral Proteins - metabolism | RNA Helicases - antagonists & inhibitors | Drosophila Proteins - physiology | Animals | RNA Interference | Ribonuclease III | Argonaute Proteins | Drosophila melanogaster - enzymology | Insect Viruses - immunology | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Drosophila Proteins - genetics | Drosophila Proteins - antagonists & inhibitors | Drosophila melanogaster - virology | Insect Viruses - genetics | Suppression, Genetic | Genetic research | Drosophila | Genetic aspects | Index Medicus | Drosophila Proteins | Innate immunity | Viral Proteins | Virology | Insect Viruses | Life Sciences | Microbiology and Parasitology | RNA Helicases | Immunology | RNA, Viral | RNA, Double-Stranded | Drosophila melanogaster | RNA-Induced Silencing Complex | Research Paper
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 4, pp. 607 - 620
In the and mammalian RNA interference pathways, siRNAs direct the protein Argonaute2 (Ago2) to cleave corresponding mRNA targets, silencing their expression.... 
PATHWAYS | RISC | PROTEIN | MESSENGER-RNA | DROSOPHILA-MELANOGASTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCED SILENCING COMPLEX | MICRORNA TARGETS | INTERFERENCE | DISTINCT ROLES | ARGONAUTE2 | CELL BIOLOGY | Oligonucleotides - genetics | RNA Helicases - metabolism | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Drosophila melanogaster - embryology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | RNA-Induced Silencing Complex - genetics | Embryo, Nonmammalian - metabolism | MicroRNAs - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | RNA, Small Interfering - chemistry | RNA Interference | Thionucleotides - chemistry | Base Sequence | Female | RNA Helicases - genetics | RNA, Double-Stranded - metabolism | Catalysis | Nucleic Acid Conformation | RNA, Double-Stranded - chemistry | Ovary - metabolism | Cell Line | Nerve Tissue Proteins | Manganese - chemistry | Mutation - genetics | Magnesium - chemistry | Oligonucleotides - metabolism | Animals | Cell-Free System | Ribonuclease III | RNA, Double-Stranded - genetics | RNA-Induced Silencing Complex - metabolism | Argonaute Proteins | MicroRNAs - genetics | Models, Genetic | Drosophila Proteins - genetics | HeLa Cells | Kinetics | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Enzymes | Messenger RNA | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 12/2016, Volume 30, Issue 23, pp. 2571 - 2580
Small RNAs regulate chromatin modification and transcriptional gene silencing across the eukaryotic kingdom. Although these processes have been well studied,... 
Epigenetics | Heterochromatin | Noncoding RNA | RNAi | Nascent transcript | DIRECTED DNA METHYLATION | noncoding RNA | UBIQUITIN LIGASE | DEVELOPMENTAL BIOLOGY | epigenetics | PIWI | GENOME | heterochromatin | CELL BIOLOGY | RITS | GENETICS & HEREDITY | GENE-EXPRESSION | E