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09/2017, Topics in Medicinal Chemistry, ISBN 9783319680903, Volume 27, 263
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art... 
RNA viruses | Medicinal Chemistry | Pharmaceutical Sciences/Technology | Chemistry | Bioorganic Chemistry
eBook
Trends in Pharmacological Sciences, ISSN 0165-6147, 02/2019, Volume 40, Issue 2, pp. 85 - 87
Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality, particularly in resource-limited settings. Treatment options for... 
RNAi | siRNA | sFLT1 | preeclampsia | preeclampsia therapeutics | hypertensive disorders of pregnancy | PHARMACOLOGY & PHARMACY | RNAI | Pregnancy | Placenta | RNA Interference | Humans | Pre-Eclampsia | Female | Vascular Endothelial Growth Factor Receptor-1 | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 1, pp. 41 - 51
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 1, pp. 4 - 7
Journal Article
Nature Nanotechnology, ISSN 1748-3387, 03/2018, Volume 13, Issue 3, pp. 214 - 219
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2018, Volume 379, Issue 1, pp. 11 - 21
Hereditary transthyretin amyloidosis is caused by the deposition of misfolded transthyretin proteins in peripheral nerves and other tissues. This phase 3 trial... 
MEDICINE, GENERAL & INTERNAL | POLYNEUROPATHY | EFFICACY | TAFAMIDIS | SAFETY | LATE-ONSET | NATURAL-HISTORY | PROGRESSION | Prealbumin - genetics | Humans | Middle Aged | Male | Amyloid Neuropathies, Familial - therapy | Infusions, Intravenous - adverse effects | Aged, 80 and over | Adult | Female | Prealbumin - analysis | Severity of Illness Index | Double-Blind Method | Amyloid Neuropathies, Familial - complications | RNA, Small Interfering - adverse effects | Polyneuropathies - therapy | Disease Progression | Administration, Intravenous | Polyneuropathies - etiology | RNA, Small Interfering - therapeutic use | Least-Squares Analysis | Quality of Life | Aged | RNAi Therapeutics | Amyloid Neuropathies, Familial - blood | Edema - chemically induced | Walk Test | Gait Disorders, Neurologic - etiology | Care and treatment | Amyloidosis | Genetic aspects | Intravenous administration | Gait | Cardiomyopathy | RNA-mediated interference | Liver | Diabetes mellitus | Body weight | Transthyretin | Diabetic neuropathy | Neuropathy | Gene expression | Polyneuropathy | Quality of life | Medicine | Neurology | Hospitals | Nutritional status | Pharmaceuticals | Index Medicus | Abridged Index Medicus | Assaigs clínics | Clinical trials | RNA | Amiloïdosi | Clinical Medicine | Neurologi | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 1, pp. 86 - 88
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2017, Volume 376, Issue 18, pp. e38 - e38
To the Editor: Fitzgerald et al. (Jan. 5 issue) 1 report that inclisiran, a long-acting RNA interference (RNAi) therapeutic inhibitor of proprotein convertase... 
MEDICINE, GENERAL & INTERNAL | RNA Interference | Humans | Serine Endopeptidases - genetics | Receptors, LDL - metabolism | Cholesterol, LDL | RNAi Therapeutics | Proprotein Convertases - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 2012, Volume 3, pp. 234 - 234
Aptamers are single-stranded nucleic acids that specifically recognize and bind tightly to their cognate targets due to their stable three-dimensional... 
Small interfering RNA | RNA aptamers | RNA interference | Systematic evolution of ligands by exponential enrichment | Targeted delivery | targeted delivery | RNAi | siRNA | SELEX
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2019, Volume 564, pp. 256 - 262
RNA interference (RNAi) is one of the most promising strategies for cancer therapeutics. The successful translation of RNAi therapeutics to a clinic setting... 
RNA interference (RNAi) | Peritoneal dissemination | Lipoplex | Short hairpin RNA (shRNA) | Freeze-drying | Presome | GENE DELIVERY | DRUG-DELIVERY | NUCLEIC-ACID | STABILIZATION | NANOMEDICINE | NANOCARRIERS | SIRNA DELIVERY | SOLID LIPID NANOPARTICLES | THERAPY | PHARMACOLOGY & PHARMACY | LIPOSOMES | Local government | RNA | Methods | Therapeutics | Homeopathy | Materia medica and therapeutics
Journal Article
Annual Review of Medicine, ISSN 0066-4219, 1/2019, Volume 70, Issue 1, pp. 307 - 321
Journal Article
Biomaterials, ISSN 0142-9612, 07/2019, Volume 210, pp. 83 - 93
Chronic infection with hepatitis B virus (HBV) is a major public health problem. Recently, RNA interfering-based strategy has shown great potential to... 
HBsAg | RNAi | Artificial miRNA | CHB | FIBROSIS | METHYLATION | DESIGN | MATERIALS SCIENCE, BIOMATERIALS | HEPATITIS-B-VIRUS | ENGINEERING, BIOMEDICAL | MICRORNAS | LEVEL | DISEASE | GROWTH | INTERFERENCE | EXPRESSION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 8, pp. 2060 - 2065
Journal Article