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Molecular Neurobiology, ISSN 0893-7648, 12/2008, Volume 38, Issue 3, pp. 253 - 269
Photoreceptor cell death is the major hallmark of a group of human inherited retinal degenerations commonly referred to as retinitis pigmentosa (RP). Although... 
rds | Oxidative stress | rd2 | Calcium | Neurobiology | Calpain | cGMP | Retina | PARP | Cell Biology | Life Sciences | Neurology | CREB | AIF | rd1 | CALCIUM-CHANNEL BLOCKER | APOPTOSIS-INDUCING FACTOR | NITRIC-OXIDE SYNTHASE | D-CIS-DILTIAZEM | ROD CGMP-PHOSPHODIESTERASE | ELEMENT-BINDING PROTEIN | ENDOPLASMIC-RETICULUM STRESS | NEUROSCIENCES | CAMP EARLY REPRESSOR | RD1 MOUSE RETINA | MEDIATED PROGRAMMED NECROSIS | Nucleotides, Cyclic - metabolism | Calpain - metabolism | Oxidative Stress | Calcium - metabolism | Retinal Degeneration - genetics | Humans | Retinitis Pigmentosa - metabolism | Transcription Factors - genetics | Retinal Degeneration - metabolism | Transcription Factors - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Endoplasmic Reticulum - pathology | Retinitis Pigmentosa - enzymology | Animals | DNA Fragmentation | Cell Death | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Photoreceptor Cells, Vertebrate - metabolism | Retinal Degeneration - pathology | Photoreceptor Cells, Vertebrate - pathology | Retinal Degeneration - enzymology | Retinitis Pigmentosa - pathology | Disease Models, Animal | Eye diseases | Apoptosis | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | REPRESSOR | Neurovetenskaper | Basic Medicine | CAMP EARLY | Medicinska och farmaceutiska grundvetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e112142
Journal Article
Journal Article
by Zeng, H and Ding, M and Chen, X.-X and Lu, Q
Neuroscience, ISSN 0306-4522, 2014, Volume 275, pp. 54 - 61
Highlights • Expression of NADPH oxidase was markedly elevated in retinal microglial cells in the rod degeneration in rd mice. • Increasing generation of... 
Neurology | NADPH | INL | RPE | inner nuclear layer | OPL | ONL | TNF | rd mice | outer nuclear layer | FITC | NADPH oxidase | ethylenediaminetetraacetic acid | reactive oxygen species | retinal pigment epithelium | fluorescein isothiocyanate | outer plexiform layer | microglia | H.E | hematoxylin and eosin | 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid | PBS | rod degeneration | ganglion cell layer | nicotinamide adenine dinucleotide phosphate | EDTA | EGTA | GCL | tetramethylrhodamine isothiocyanate | tumor necrosis factor | HEPES | Nox | phosphate buffered saline | ROS | retinitis pigmentosa | ethylene glycol tetraacetic acid | TRITC | Rd mice | Rod degeneration | Microglia | OXIDATIVE STRESS | MOUSE | DOPAMINERGIC-NEURONS | KAPPA-B | MODEL | NEUROTOXICITY | NEUROSCIENCES | GENE-EXPRESSION | RETINITIS-PIGMENTOSA | ROTENONE-INDUCED DEGENERATION | PARKINSONS-DISEASE | Animals | NADPH Oxidases - metabolism | Retinal Rod Photoreceptor Cells - enzymology | Superoxides - metabolism | Microglia - enzymology | Mice | Apoptosis - physiology | Retinal Degeneration - pathology | Retinal Degeneration - enzymology | Retinal Rod Photoreceptor Cells - pathology | Oxidases | Physiological aspects | Biochemistry | Superoxide | Cell death | Phosphates | Niacinamide | Ethylene glycol | Nervous system diseases | Analysis | Fluorescein | Retinal degeneration | Index Medicus
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 20, p. 5259
Retinitis pigmentosa (RP) is an inherited neurodegenerative disease, in which the death of mutant rod photoreceptors leads secondarily to the non-cell... 
Cell culture | Therapy | Animal models | Gene transfer | Retinitis pigmentosa | Mortality | Retina | Segments | Rods | Patients | Survival | Defects | Cones | Neurodegeneration | Efficiency | Cell death | Genetics | Eye diseases | Photoreceptors | Retinitis | Gene therapy | Apoptosis
Journal Article