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Nature Genetics, ISSN 1061-4036, 07/2006, Volume 38, Issue 7, pp. 794 - 800
Journal Article
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 7245 - 10
Activation of cGMP phosphodiesterase (PDE) by activated transducin alpha subunit (T alpha*) is a necessary step to generate a light response in vertebrate... 
MECHANISM | ROD OUTER SEGMENT | KINETICS | MULTIDISCIPLINARY SCIENCES | PARAMETERS | G-PROTEIN | CYCLIC-GMP PHOSPHODIESTERASE | Trapping | Cyclic GMP | Transducin | Photoreceptors | Rods | Kinases | Binding sites | Phosphodiesterase | Catalytic subunits
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2009, Volume 28, Issue 22, pp. 3613 - 3622
The inhibitory interaction of phosphodiesterase‐6 (PDE6) with its γ‐subunit (Pγ) is pivotal in vertebrate phototransduction. Here, crystal structures of a... 
transducin | X‐ray crystallography | phototransduction | phosphodiesterase 6 | X-ray crystallography | Transducin | Phosphodiesterase 6 | Phototransduction | PDE6 | MAXIMUM-LIKELIHOOD | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | ROD CGMP-PHOSPHODIESTERASE | CATALYTIC SUBUNITS | G-PROTEIN | CYCLIC-GMP PHOSPHODIESTERASE | CELL BIOLOGY | ENZYME | DOMAINS | Cyclic Nucleotide Phosphodiesterases, Type 5 - chemistry | Humans | Cyclic Nucleotide Phosphodiesterases, Type 6 - antagonists & inhibitors | Molecular Sequence Data | Cyclic Nucleotide Phosphodiesterases, Type 6 - chemistry | Peptide Fragments - pharmacology | Piperazines - metabolism | Piperazines - chemistry | Structure-Activity Relationship | Sulfones - pharmacology | Recombinant Fusion Proteins - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 6 - physiology | Sildenafil Citrate | 1-Methyl-3-isobutylxanthine - chemistry | Cattle | Sulfones - chemistry | Enzyme Inhibitors - chemistry | Protein Subunits - physiology | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Amino Acid Sequence | Catalytic Domain | Cyclic Nucleotide Phosphodiesterases, Type 6 - metabolism | Peptide Fragments - metabolism | Enzyme Inhibitors - metabolism | Purines - metabolism | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Models, Molecular | Sulfones - metabolism | Recombinant Fusion Proteins - chemistry | Piperazines - pharmacology | 1-Methyl-3-isobutylxanthine - pharmacology | Sequence Homology, Amino Acid | Peptide Fragments - chemistry | Animals | Purines - chemistry | Protein Binding | Protein Subunits - chemistry | 1-Methyl-3-isobutylxanthine - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 19, pp. 19800 - 19807
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2009, Volume 106, Issue 43, pp. 18225 - 18230
Journal Article
Journal Article