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Educational Forum - Coxibs: The new super aspirins or unsafe pain killers?, 12/2005
The new generation of analgesics and antiinflammatory drugs, namely, the selective inhibitors of cyclooxygenase-2 (COX-2) enzymes, popularly known as Coxibs,... 
Adverse effects, COX-2 inhibitors, NSAIDs, rofecoxib
Journal
Study - Management of premenstrual acne with Cox-2 inhibitors: A placebo controlled study, 11/2004
BACKGROUND: Premenstrual acne is poorly understood, the accepted hypothesis is 30 years old. AIMS: Here we test the hypothesis that premenstrual acne can be... 
Premenstrual acne, Rofecoxib, Prostaglandin dv04120 | Dermatology
Journal
NATURE REVIEWS RHEUMATOLOGY, ISSN 1759-4790, 03/2017, Volume 13, Issue 3, pp. 136 - 138
The PRECISION trial demonstrates that celecoxib is noninferior to ibuprofen and naproxen in regard to cardiovascular safety. Do these findings mark the end of... 
ARTHRITIS | ROFECOXIB | RHEUMATOLOGY
Journal Article
03/2008
Objectives: To investigate the effects of meloxicam and rofecoxib on psychomotor performance in young, healthy volunteers. Materials and Methods: This study... 
Meloxicam | rofecoxib | psychomotor performance
Web Resource
Journal of the American College of Surgeons, ISSN 1072-7515, 2016, Volume 223, Issue 4, pp. S52 - S53
Journal Article
Journal Article
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, ISSN 0098-7484, 10/2006, Volume 296, Issue 13, pp. 1633 - 1644
Context Evidence that rofecoxib increases the risk of myocardial infarction has led to scrutiny of other nonsteroidal anti-inflammatory drugs ( NSAIDs).... 
RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | GENERAL-POPULATION | EVENTS | METAANALYSIS | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ACUTE MYOCARDIAL-INFARCTION | CYCLO-OXYGENASE-2 INHIBITORS | ROFECOXIB | CORONARY HEART-DISEASE | ASPIRIN
Journal Article
Pharmacoepidemiology and Drug Safety, ISSN 1053-8569, 2019
The period of time during which a patient is exposed to a drug does not necessarily correspond to the period during which the drug produces the adverse effect... 
rofecoxib | exposure | time windows | myocardial infarction | pharmacology | misclassification | pharmacoepidemiology
Journal Article
Annals of Oncology, ISSN 0923-7534, 01/2013, Volume 24, Issue 1, pp. 179 - 185
The intra-tumor stroma percentage in colon cancer (CC) patients has previously been reported by our group as a strong independent prognostic parameter.... 
ASCO | Stroma | Pathology | VICTOR | Colon cancer | Prognostic | ADJUVANT CHEMOTHERAPY | SURVIVAL | pathology | EVENTS | colon cancer | stroma | RANDOMIZED-TRIAL | CHEMOPREVENTION | MICROSATELLITE-INSTABILITY | FLUOROURACIL | prognostic | THERAPY | ONCOLOGY | COLORECTAL-CANCER | ROFECOXIB | Prognosis | Double-Blind Method | Stromal Cells - pathology | Colonic Neoplasms - pathology | Humans | Survival Analysis | Index Medicus
Journal Article
Neurology, ISSN 0028-3878, 04/2019, Volume 92, Issue 18, pp. e2070 - e2080
OBJECTIVETo evaluate the safety and efficacy of low-dose naproxen for prevention of progression in presymptomatic Alzheimer disease (AD) among cognitively... 
NONSTEROIDAL ANTIINFLAMMATORY DRUGS | TRAJECTORIES | SYMPTOM ONSET | MRI DATA | RISK | ROFECOXIB | MILD COGNITIVE IMPAIRMENT | CLINICAL NEUROLOGY | Null Hypothesis
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 08/2013, Volume 33, Issue 8, pp. 1674 - 1685
Journal Article
The Oncologist, ISSN 1083-7159, 01/2018, Volume 23, Issue 1, pp. 2 - e5
经验总结 • 结直肠癌具有高环氧合酶‐2(COX‐2)表达水平, 存在强有力的临床前证据表明, 抑制COX‐2表达可改善结直肠癌的临床结局。塞来昔布是COX‐2抑制剂, 已有研究证实塞来昔布可以安全地联合卡培他滨与奥沙利铂作为新辅助治疗的一部分, 联合放疗用于治疗直肠癌。 • 与历史数据相比,... 
PREOPERATIVE CHEMORADIATION | LUNG | CYCLOOXYGENASE-2 | THERAPY | ONCOLOGY | COLORECTAL-CANCER | POSTOPERATIVE CHEMORADIOTHERAPY | RANDOMIZED-TRIAL | ROFECOXIB | BREAST | Clinical Trial Results
Journal Article
JAMA Internal Medicine, ISSN 2168-6106, 11/2018, Volume 178, Issue 11, pp. 1516 - 1525
IMPORTANCE International nephrology societies advise against nonsteroidal anti-inflammatory drug (NSAID) use in patients with hypertension, heart failure, or... 
MEDICINE, GENERAL & INTERNAL | PAIN | MANAGEMENT | CARDIOVASCULAR EVENTS | ACUTE MYOCARDIAL-INFARCTION | RISK PATIENTS | ROFECOXIB | INHIBITORS | DIURETICS | CARE | HOSPITALIZATION | Index Medicus | Abridged Index Medicus
Journal Article
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