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rolofylline (71) 71
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cardiac & cardiovascular systems (58) 58
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adenosine (13) 13
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pharmacology & pharmacy (7) 7
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adenosine a1 receptor antagonists (6) 6
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cardiology and cardiovascular medicine (5) 5
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Journal of the American College of Cardiology, ISSN 0735-1097, 05/2011, Volume 57, Issue 19, pp. 1899 - 1907
Objectives: This study sought to assess the effects of rolofylline on renal function in patients with acute heart failure (AHF) and renal dysfunction... 
heart failure | renal function | adenosine receptor antagonist | diuretics | rolofylline
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 2017, Volume 25, Issue 6, pp. 1963 - 1975
Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate III. Several potent and... 
Diuresis | Adenosine | Glomerular | BG-9928 | Rolofylline | Hypoxanthine
Journal Article
Lancet, The, ISSN 0140-6736, 01/2013, Volume 381, Issue 9860, pp. 29 - 39
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 03/2017, Volume 25, Issue 6, pp. 1963 - 1975
Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate . Several potent and... 
Rolofylline | Diuresis | Hypoxanthine | Adenosine | Glomerular | BG-9928
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2016, Volume 113, Issue 41, pp. 11597 - 11602
Accumulation of Tau is a characteristic hallmark of several neurodegenerative diseases but the mode of toxic action of Tau is poorly understood. Here, we show... 
treatment | CELLS | hypoactivity | PROTEIN | rolofylline | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | FRONTOTEMPORAL DEMENTIA | BETA-STRUCTURE | axons | MEMORY | ADENINE-NUCLEOTIDES | tauopathies | CENTRAL-NERVOUS-SYSTEM | INDUCIBLE MOUSE MODELS | DETERMINES AGGREGATION
Journal Article
Journal Article
European Heart Journal, ISSN 0195-668X, 05/2014, Volume 35, Issue 19, pp. 1284 - +
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 11/2016, Volume 223, pp. 967 - 975
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 04/2017, Volume 57, Issue 4, pp. 440 - 451
We studied safety and tolerability of neladenoson bialanate, a novel oral selective partial adenosine A1 receptor agonist that maintains the cardioprotective... 
heart failure | STIMULATION | ANTAGONIST | MECHANISM | REPERFUSION | ISCHEMIA | ADENOSINE RECEPTORS | partial adenosine A1 receptor agonist | ROLOFYLLINE | AV block | IN-VIVO | cardioprotection | neladenoson bialanate | ADENOSINE | PHARMACOLOGY & PHARMACY
Journal Article
Journal Article
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2019, Volume 25, Issue 26, pp. 2792 - 2807
Background: Adenosine mediates various physiological and pathological conditions by acting on its four P-1 receptors (A(1), A(2A), A(2B) and A(3) receptors).... 
antagonists | ANTAGONIST ROLOFYLLINE | NELADENOSON BIALANATE | Adenosine | A ADENOSINE RECEPTOR | SAFETY | OPEN-LABEL | P-1-receptors | ACUTE HEART-FAILURE | PARTIAL ADENOSINE-A1-RECEPTOR AGONIST | HEPATOCELLULAR-CARCINOMA | agonists | regadenoson | clinical-trials | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | PARKINSONS-DISEASE
Journal Article
Journal Article