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Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 1/2019, Volume 202, Issue 1, pp. 79 - 92
The role of retinoid-related orphan receptor gamma t (RORγt) in Th17 cell differentiation has been well-established, however, how it regulates other T cell... 
colitis | Blimp-1 | IL-10 | RORγt | Th17 cells
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 276
T helper 17 (Th17) cells play a complex and controversial role in tumor immunity and have been found to exhibit a fluctuating identity within the context of... 
Tumor microenvironment | Immunotherapy | Plasticity | RORyt | Il-17A | Th17 | Cancer | Tumor Microenvironment | plasticity | IL-17A
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 12/2019, Volume 337, p. 577046
The aim of the current study is to evaluate IL-17 production and RORγT, and IL-23R expression by iNKT, Th17 and γδ T cells in the peripheral blood of... 
γδ T | Multiple sclerosis | Th17 | iNKT | IL-17 | RORγT
Journal Article
Oncotarget, 2016, Volume 7, Issue 39, pp. 63261 - 63282
Journal Article
Modern Rheumatology, ISSN 1439-7595, 09/2018, Volume 28, Issue 5, pp. 814 - 825
Objectives: To clarify the pathogenic role of transcription factor expression of CD4 + T helper (Th) cell subsets in the development of rheumatoid arthritis... 
CCR6 | Th17 cell | CCL20 | RORγt
Journal Article
Molecules, ISSN 1420-3049, 12/2018, Volume 23, Issue 12, p. 3181
As an attractive drug-target, retinoic acid receptor-related orphan receptor-gamma-t (RORγt) has been employed widely to develop clinically relevant small... 
Agonist | Molecular mechanism of action (MOA) | Inverse agonist | RORγt | molecular mechanism of action (MOA) | agonist | inverse agonist
Journal Article
Annual review of pharmacology and toxicology, ISSN 0362-1642, 1/2020, Volume 60, Issue 1, pp. 371 - 390
Retinoic acid-related orphan receptor γt (RORγt) functions as a ligand-dependent transcription factor that regulates multiple proinflammatory genes and plays a... 
retinoic acid-related orphan receptor | cholesterol biosynthesis | inflammation | RORγ | (inverse) agonists | autoimmune disease | Th17 cells | Index Medicus
Journal Article
Cell Reports, 12/2018, Volume 25, Issue 13, pp. 3733 - 3749.e8
RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (T 17) cell development. However, the cell-intrinsic mechanisms that... 
circadian | autoimmunity | IL-17A | REV-ERB | T cells | Th17 | RORγt | SR9009
Journal Article
BioEssays, ISSN 0265-9247, 12/2016, Volume 38, Issue 12, pp. 1193 - 1194
Journal Article
Immunopharmacology and Immunotoxicology, ISSN 0892-3973, 12/2012, Volume 34, Issue 6, pp. 1039 - 1046
Journal Article
Microbial Pathogenesis, ISSN 0882-4010, 01/2020, Volume 138, p. 103826
Tangeretin, a polymethoxylated flavonoid is abundant in citrus fruits, which has been reported to inhibit inflammation by inhibiting NF-κB activation and... 
Acute lung injury | IL-23R | Th17 | Tangeretin | Notch | RORγt
Journal Article