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Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 10/2017, Volume 173, pp. 42 - 56
The classical pathway of vitamin D activation follows the sequence D3 → 25(OH)D3 → 1,25(OH) D3 with the final product acting on the receptor for vitamin D... 
RORγ | 1,25D3-MARRS | RORα | Hydroxyvitamin D | CYP11A1 | VDR
Journal Article
Journal of Dermatological Science, ISSN 0923-1811, 03/2019, Volume 93, Issue 3, pp. 176 - 185
Retinoic acid receptor-related orphan receptor gamma t (RORγt) has critical roles in the development, maintenance and function of interleukin (IL)-17-producing... 
Thymic lymphoma | Psoriasis | IL-17 | RORγt
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 276
T helper 17 (Th17) cells play a complex and controversial role in tumor immunity and have been found to exhibit a fluctuating identity within the context of... 
Tumor microenvironment | Immunotherapy | Plasticity | RORyt | Il-17A | Th17 | Cancer | Tumor Microenvironment | plasticity | IL-17A
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 12/2019, Volume 337, p. 577046
The aim of the current study is to evaluate IL-17 production and RORγT, and IL-23R expression by iNKT, Th17 and γδ T cells in the peripheral blood of... 
γδ T | Multiple sclerosis | Th17 | iNKT | IL-17 | RORγT
Journal Article
Oncotarget, 2016, Volume 7, Issue 39, pp. 63261 - 63282
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 182, p. 111589
A series of aryl-substituted indole and indoline derivatives were discovered as novel RORγt agonists by a scaffold-based hybridization of the reported RORγt... 
Metabolic stability | Indoles | RORγt agonists | Cancer immunotherapy | Aqueous solubility | Indolines
Journal Article
Modern Rheumatology, ISSN 1439-7595, 09/2018, Volume 28, Issue 5, pp. 814 - 825
Objectives: To clarify the pathogenic role of transcription factor expression of CD4 + T helper (Th) cell subsets in the development of rheumatoid arthritis... 
CCR6 | Th17 cell | CCL20 | RORγt
Journal Article
Molecules, ISSN 1420-3049, 12/2018, Volume 23, Issue 12, p. 3181
As an attractive drug-target, retinoic acid receptor-related orphan receptor-gamma-t (RORγt) has been employed widely to develop clinically relevant small... 
Agonist | Molecular mechanism of action (MOA) | Inverse agonist | RORγt | molecular mechanism of action (MOA) | agonist | inverse agonist
Journal Article
BioEssays, ISSN 0265-9247, 12/2016, Volume 38, Issue 12, pp. 1193 - 1194
Journal Article
Immunopharmacology and Immunotoxicology, ISSN 0892-3973, 12/2012, Volume 34, Issue 6, pp. 1039 - 1046
Journal Article