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Frontiers in Oncology, ISSN 2234-943X, 2012, Volume 2, p. 34
Targeted therapies require cellular protein expression that meets specific requirements that will maximize effectiveness, minimize off-target toxicities, and... 
Solid tumor | Receptor tyrosine kinase orphan receptors (ROR1/ROR2) | Immunotherapy | Wnt/beta-catenin | ROR1/ROR2 | Wnt/Beta-Catenin | receptor tyrosine kinase orphan receptors
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2019, Volume 203, Issue 8, pp. 2043 - 2048
Inhibitors of Bruton tyrosine kinase (BTK), a kinase downstream of BCR, display remarkable activity in a subset of mantle cell lymphoma (MCL) patients, but the... 
SAFETY | CD19 | IBRUTINIB | RESISTANCE | ROR1 | IMMUNOLOGY | TARGETING BTK
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 11/2019, Volume 119, p. 109420
Over-expression of Receptor-tyrosine-kinase-like Orphan Receptor 1 (ROR1) in cancer cells has been reported in the context of several tumors (including ovarian... 
ROR1 | Monoclonal antibody | Immunotherapy | Ovarian cancer | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | CISPLATIN | TYROSINE KINASES ROR1 | CHRONIC LYMPHOCYTIC-LEUKEMIA | RECEPTOR | PHARMACOLOGY & PHARMACY
Journal Article
Immunology Letters, ISSN 0165-2478, 01/2018, Volume 193, pp. 35 - 41
Immunotherapy with tumor-associated antigens (TAAs) is a potentially powerful approach to eradicate tumor cells. The receptor tyrosine kinase-like orphan... 
ROR1 | Syngeneic tumor model | Tumor-associated antigen | Anti-ROR1 antibody | TARGET | APOPTOSIS | CELLS | SAFETY | IMMUNOLOGY | CANCER | CHRONIC LYMPHOCYTIC-LEUKEMIA | MONOCLONAL-ANTIBODIES | EXPRESSION | RECEPTOR TYROSINE KINASE
Journal Article
BioFactors, ISSN 0951-6433, 05/2019, Volume 45, Issue 3, pp. 416 - 426
The receptor‐tyrosine‐kinase (RTK)‐like orphan receptor 1 (ROR1) is a transmembrane glycoprotein regarded as a tumor‐associated antigen. ROR1 plays an... 
apoptosis | DLBCL | ROR1 | proliferation | shRNA | MIGRATION | SURVIVAL | ANTIGEN ROR1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBODY | TYROSINE KINASES | CANCER | CELL LYMPHOMA | ENDOCRINOLOGY & METABOLISM | TARGETS | EXPRESSION | Development and progression | Lymphomas | Prognosis
Journal Article
Cell Stem Cell, ISSN 1934-5909, 06/2018, Volume 22, Issue 6, pp. 951 - 959.e3
Cirmtuzumab is a humanized monoclonal antibody (mAb) that targets ROR1, an oncoembryonic orphan receptor for Wnt5a found on cancer stem cells (CSCs). Aberrant... 
WNT5A INDUCES ROR1 | CHEMOTAXIS | RITUXIMAB | HS1 | C-MYC | SELF-RENEWAL | RECEPTOR | CELL | EXPRESSION | CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2019, Volume 14, Issue 5
Triple Negative Breast Cancer (TNBC), the most aggressive subtype of breast cancer, is characterized by the absence of hormone receptors usually targeted by... 
APOPTOSIS | ACCURATE DOCKING | PHOSPHORYLATION | PATHWAY | PROTEIN-STRUCTURE | MULTIDISCIPLINARY SCIENCES | GLIDE | ROR1 | PREDICTION
Journal Article
Advances in Biological Regulation, ISSN 2212-4926, 10/2019, p. 100669
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 06/2019, Volume 29, Issue 6, pp. 449 - 451
Glucocorticoids (GCs)are widely used for the management of disease- or therapy-related complications in cancer patients. Recent data indicate that activation... 
ROR1 | triple negative breast cancer | social stress | circulating tumor cells | dormancy | immunotherapy
Journal Article
Blood, ISSN 0006-4971, 07/2018, Volume 132, Issue 2, pp. 115 - 116
In this issue of Blood, Hasan et al demonstrate that dedicator of cytokinesis 2 (DOCK2) can complex with receptor tyrosine kinase like orphan receptor 1 (ROR1)... 
MIGRATION | CELLS | PROTEIN | CHRONIC LYMPHOCYTIC-LEUKEMIA | RECEPTOR | ROR1 | HEMATOLOGY
Journal Article
Placenta, ISSN 0143-4004, 07/2019, Volume 82, pp. 17 - 24
Invasive deficiency of the trophoblast and poor remodeling of the uterine spiral arteries were probably the primary pathogenesis causes of preeclampsia (PE).... 
ROR1 | Trophoblast | Placenta | PI3K/AKT/mTOR | Preeclampsia | Invasion | Immunohistochemistry | Tyrosine | Phenols | Obstetrics
Journal Article
BLOOD, ISSN 0006-4971, 09/2019, Volume 134, Issue 13, pp. 1084 - 1094
Coculture of nurse-like cells (NLCs) with chronic lymphocytic leukemia (CLL) cells induced leukemia cell phosphorylation of STAT3 (pSTAT3), which could be... 
NURSELIKE CELLS | SIGNATURES | CHEMOTAXIS | TRANSCRIPTION | RECEPTOR | ROR1 | PROLIFERATION | INTERLEUKIN-6 | HEMATOLOGY | EXPRESSION | PROGRESSION
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2017, Volume 429, Issue 19, pp. 2954 - 2973
Journal Article