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PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 11, pp. 1038 - 1046
Journal Article
Stem Cell Research, ISSN 1873-5061, 05/2015, Volume 14, Issue 3, pp. 243 - 257
Stem cell therapies are being explored extensively as treatments for degenerative eye disease, either for replacing lost neurons, restoring neural circuits or,... 
NEUROTROPHIC FACTOR | TRANSECTED SPINAL-CORD | OPTIC-NERVE CRUSH | VERSUS-HOST-DISEASE | PROMOTE LOCOMOTOR RECOVERY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | RETINAL GANGLION-CELLS | MESENCHYMAL STROMAL CELLS | HUMAN BONE-MARROW | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PIGMENT EPITHELIUM | IN-VITRO DIFFERENTIATION | Cell- and Tissue-Based Therapy - methods | Stem Cells - immunology | Retinal Ganglion Cells - physiology | Humans | Induced Pluripotent Stem Cells - transplantation | Dental Pulp - cytology | Stem Cell Transplantation | Retinal Ganglion Cells - cytology | Retina - cytology | Embryonic Stem Cells - transplantation | Neural Stem Cells - transplantation | Graft Rejection | Eye Diseases - pathology | Mesenchymal Stem Cell Transplantation | Regeneration - immunology | Eye Diseases - therapy | GFAP, glial fibrillary acidic protein | EGF, epidermal growth factor | NSCs, neural stem cells | SCI, spinal cord injury | NGF, nerve growth factor | Review | iPSCs, induced pluripotent stem cells | ivit, intravitreal | mTOR, mammalian target of rapamycin | ONL, outer nuclear layer | RGC, retinal ganglion cell | NTFs, neurotrophic factors | VEGF, vascular endothelial growth factor | AMD, age-related macular degeneration | DPSC, dental pulp stem cells | FGF, fibroblast growth factor | NT-3, neurotrophin-3 | CNS, central nervous system | BDNF, brain-derived neurotrophic factor | GDNF, glial cell line-derived neurotrophic factor | ERG, electroretinogram | TBI, traumatic brain injury | RPE, retinal pigment epithelial cells | BMSCs, bone marrow-derived stem cells | CNTF, ciliary neurotrophic factor | MSC, mesenchymal stem cells | ESCs, embryonic stem cells | TrK, tropomyosin related kinase | RCS, Royal College of Surgeons rats | ADSCs, adipose-derived stem cells
Journal Article
Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2427 - 2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem... 
Retinal pigmented epithelium | Age-related macular degeneration | Induced pluripotent stem cells | Retinitis pigmentosa | ISOMEROHYDROLASE | ROD OUTER SEGMENTS | PHAGOCYTOSIS | MACULAR DEGENERATION | retinal pigmented epithelium | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MICROSOMAL PROTEIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | retinitis pigmentosa | induced pluripotent stem cells | RPE CELLS | DIFFERENTIATION | HEMATOLOGY | age-related macular degeneration | EYE DEVELOPMENT | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - analysis | Retinal Diseases - therapy | RNA, Messenger - analysis | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - pharmacology | Homeodomain Proteins - pharmacology | Cell Differentiation - physiology | Integrin alphaV - metabolism | Biomarkers - metabolism | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Biomarkers - analysis | Octamer Transcription Factor-3 - pharmacology | Phagocytosis - physiology | Regeneration - physiology | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Retinal Rod Photoreceptor Cells - cytology | Cell Polarity - physiology | Brain Tissue Transplantation - methods | Retinal Pigment Epithelium - cytology
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0158282
Journal Article
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 04/2018, Volume 59, Issue 5, pp. 1719 - 1731
PURPOSE. To determine whether human induced pluripotent stem (iPS) cell-derived retinal pigment epithelial (RPE) cells (iPS-RPE) can suppress natural killer... 
IPS cells | Natural killer cells | RPE cells | Suppression | ACTIVATION | IMMUNE PRIVILEGE | MACULAR DEGENERATION | RECEPTOR | BEHCETS-DISEASE | T-CELL | VIRAL-INFECTION | iPS cells | TRANSPLANTATION | ANTERIOR-CHAMBER | natural killer cells | NK CELLS | suppression | OPHTHALMOLOGY
Journal Article
STEM CELLS Translational Medicine, ISSN 2157-6564, 05/2013, Volume 2, Issue 5, pp. 341 - 354
Journal Article
Stem Cell Research and Therapy, ISSN 1757-6512, 10/2017, Volume 8, Issue 1, pp. 217 - 17
Background: Dysfunction of the retinal pigment epithelium (RPE) is implicated in numerous forms of retinal degeneration. The readily accessible environment of... 
RPE cytoskeleton | Live-cell imaging | Induced pluripotent stem cells | Phagocytosis | Retinal pigment epithelium | MEDICINE, RESEARCH & EXPERIMENTAL | DIRECTED DIFFERENTIATION | PHAGOSOME MATURATION | USHER-SYNDROME 1B | MACULAR DEGENERATION | EFFICIENT GENERATION | OUTER SEGMENTS | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | MOLECULAR SIGNATURE | TIGHT JUNCTIONS | RETINAL-PIGMENT EPITHELIUM | Skin - cytology | Fibroblasts - physiology | Epithelial Cells - drug effects | Humans | Epithelial Cells - physiology | Encephalitis Virus, Venezuelan Equine - genetics | Retinal Pigment Epithelium - physiology | Cell Polarity - drug effects | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Cellular Reprogramming - genetics | Disease Models, Animal | Encephalitis Virus, Venezuelan Equine - metabolism | Retinal Pigment Epithelium - drug effects | Epithelial Cells - transplantation | Genetic Vectors - chemistry | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Genetic Vectors - metabolism | Retinal Degeneration - physiopathology | Mice, Knockout | Animals | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Retinal Degeneration - therapy | Fibroblasts - cytology | Mice | Mice, Inbred BALB C | Primary Cell Culture | Retinal Degeneration - pathology | Injections, Intraocular | Retinal Pigment Epithelium - cytology | Transplantation | Research | Cell differentiation | Health aspects | Stem cells | Cell culture | Motility | Disease | Laboratories | Stem cell transplantation | Retina | Genomes | Macular degeneration | Eye | Proteins | Allografts | Rodents | Fibroblasts | Polarity | Growth factors | Autografts | Integration | Gene expression | Epithelium | Ribonucleic acid--RNA</