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Acta Ophthalmologica, ISSN 1755-375X, 09/2017, Volume 95, Issue 6, pp. e443 - e452
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency
Journal Article
Eye (Basingstoke), ISSN 0950-222X, 08/2015, Volume 29, Issue 8, pp. 992 - 1002
Journal Article
Acta Ophthalmologica, ISSN 1755-375X, 08/2019, Volume 97, Issue 5, pp. e688 - e699
Purpose To study immunogenic properties of human embryonic stem cell–derived retinal pigment epithelium (hESC‐RPE) and to evaluate subretinal... 
age‐related macular degeneration | RPE transplantation | xeno‐free | cell therapy | pluripotent stem cell | age-related macular degeneration | xeno-free | MATRIX | STIMULATION | RPE | SUBRETINAL IMPLANTATION | AUTOLOGOUS TRANSLOCATION | PATCH | DEGENERATION | OPHTHALMOLOGY | THERAPIES | ALBUMIN | Cell Line | Human Embryonic Stem Cells - transplantation | Rabbits | Retinal Pigment Epithelium - transplantation | Follow-Up Studies | Cell Survival | Tomography, Optical Coherence | Human Embryonic Stem Cells - cytology | Humans | Male | Transplantation, Heterologous | Tissue Scaffolds | Stem Cell Transplantation - methods | Animals | Polyesters | Retinal Diseases - pathology | Female | Cell Differentiation | Phagocytosis | Retinal Diseases - surgery | Retinal Pigment Epithelium - cytology | Disease Models, Animal | Macular degeneration | Corticosteroids | Wildlife conservation | Immunotherapy | Stem cells | Polyethylene terephthalate | Transplantation | Interferon | Biological response modifiers | Embryonic stem cells | Xenotransplantation | Retina | Stimulation | Retinal pigment epithelium | Proteins | Atrophy | Xenografts | Eye (anatomy) | Polyethylene | Statistical analysis | Cell survival | Preservation | Retinal cells | Histology | Epithelium | Survival | Substrates | Immunosuppression | Transmission electron microscopy | Major histocompatibility complex | Optical Coherence Tomography | Immunogenicity | Tacrolimus | Morphology | Histocompatibility | Vacuoles
Journal Article
Retina (Philadelphia, Pa.), ISSN 0275-004X, 09/2018, Volume 38, Issue Suppl 1, pp. S12 - S22
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 08/2019, Volume 106, pp. 7 - 14
This study aimed to determine the safety and tolerability of the subretinal injection of hESC-derived RPE cells at higher doses than the established clinical... 
Preclinical study | hESC-derived RPE cell | Minipig | Age-related macular degeneration | Subretinal injection | Macular degeneration | Immunohistochemistry | Viral antibodies | Medical colleges | Safety and security measures | Stem cells | Antibodies | Transplantation | Embryonic stem cells
Journal Article