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Biochemical Journal, ISSN 0264-6021, 01/2007, Volume 401, Issue 1, pp. 29 - 38
Hormones and growth factors induce the activation of a number of protein kinases that belong to the AGC subfamily, including isoforms of PKA, protein kinase B... 
Kinase-specific inhibitor | Phosphorylation | p90 ribosomal S6 kinase (RSK) | BI-D1870 | Mitogen-activated protein kinase (MAPK) | ACTIVATED PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | mitogen-activated protein kinase (MAPK) | MSK1 | INDUCTION | IDENTIFICATION | INACTIVATION | CREB | GROWTH | BI-DI870 | SUPPRESSES | phosphorylation | kinase-specific inhibitor | Cell Line | Pteridines - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Ribosomal Protein S6 Kinases, 90-kDa - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Kinetics | Chromones - pharmacology | Isoenzymes - antagonists & inhibitors | Index Medicus | MES, mouse embryonic stem | PI3K, phosphoinositide 3-kinase | EGF, epidermal growth factor | PKA, cAMP-dependent protein kinase A | FKHR, forkhead in rhabdosarcoma transcription factor | RSK, p90 ribosomal S6 kinase | JNK, c-Jun N-terminal kinase | CREB, cAMP-response-element-binding protein | SGK1, serum- and glucocorticoid-induced kinase-1 | PDK1, phosphoinositide-dependent kinase 1 | PKB, protein kinase B | Lck, lymphocyte kinase | ROCK, Rho-dependent protein kinase | MKK1, MAPK kinase-1 | protein kinase G | AGC, cAMP-dependent protein kinase | protein kinase C | HEK-293, human embryonic kidney 293 | ERK1, extracellular-signal-regulated kinase 1 | GST, glutathione S-transferase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | PH, pleckstrin homology | PLK1, polo-like kinase 1 | CK1, casein kinase-1 | FBS, foetal bovine serum | MSK, mitogen- and stress-activated protein kinase | CDK2–A, cyclin-dependent kinase 2 complexed with cyclin A | DYRK1a, dual-specificity tyrosine-phosphorylated and -regulated kinase 1a | GSK3α, glycogen synthase kinase 3α | MAPK, mitogen-activated protein kinase
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 41, pp. E6290 - E6297
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 05/2019, Volume 294, Issue 28, pp. 10846 - 10862
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 1, pp. 11 - 27
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 01/2013, Volume 112, Issue 1, pp. 128 - 139
RATIONALE:Cardiac myocyte hypertrophy is the main compensatory response to chronic stress on the heart. p90 ribosomal S6 kinase (RSK) family members are... 
PATHWAYS | CARDIAC & CARDIOVASCULAR SYSTEMS | ACTIVATED PROTEIN-KINASE | compartmentalization | PHOSPHORYLATION | MUSCLE | DILATED CARDIOMYOPATHY | EXTRACELLULAR SIGNAL | RSK | MAKAP-BETA | IN-VIVO | concentric | PERIPHERAL VASCULAR DISEASE | p90 ribosomal S6 kinase | cardiac hypertrophy | INHIBITOR | HEMATOLOGY | Immunoprecipitation | Humans | Cercopithecus aethiops | Ribosomal Protein S6 Kinases, 90-kDa - deficiency | Cardiomegaly - pathology | Male | Isoproterenol | Myocytes, Cardiac - enzymology | A Kinase Anchor Proteins - genetics | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Transfection | RNA Interference | HEK293 Cells | Female | Protein Interaction Domains and Motifs | Binding Sites | A Kinase Anchor Proteins - metabolism | Disease Models, Animal | Animals, Newborn | Transduction, Genetic | Signal Transduction | Mice, Inbred C57BL | Rats | Genotype | Cardiomegaly - enzymology | Rats, Sprague-Dawley | Mice, Knockout | Protein Interaction Mapping | Myocytes, Cardiac - pathology | Phenotype | Animals | Cardiomegaly - prevention & control | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Adaptor Proteins, Signal Transducing - genetics | Cardiomegaly - chemically induced | Mice | Adaptor Proteins, Signal Transducing - metabolism | Cardiomegaly - genetics | COS Cells | Index Medicus | Compartmentalization | mAKAP
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0164343 - e0164343
Ribosomal S6 kinases (RSK) play important roles in cell signaling through the mitogen-activated protein kinase (MAPK) pathway. Each of the four RSK isoforms... 
ISCHEMIA-REPERFUSION INJURY | AGC KINASES | ACTIVATION | TYROSINE PHOSPHORYLATION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | MOTIF PHOSPHORYLATION | CANCER-CELL-PROLIFERATION | P90 RSK | HEMATOPOIETIC TRANSFORMATION | INHIBITOR | Phosphorylation | Humans | Mice, Inbred C57BL | Male | 3-Phosphoinositide-Dependent Protein Kinases - metabolism | Recombinant Fusion Proteins - chemistry | Ribosomal Protein S6 Kinases, 90-kDa - chemistry | Recombinant Fusion Proteins - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Escherichia coli - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Cloning, Molecular | Recombinant Fusion Proteins - genetics | Mice | Enzyme Activation | Mutation | Mitogen-Activated Protein Kinase 1 - metabolism | Genetic aspects | Protein kinases | Mitogens | Protein binding | Escherichia coli | Multiple myeloma | Smooth muscle | Catalytic activity | Regulatory sequences | Kinases | Coffin-Lowry syndrome | Skin cancer | Proteins | E coli | Proteolysis | Rodents | Bacteria | Physiology | Catalysis | Fusion protein | Hypertension | Extracellular signal-regulated kinase | MAP kinase | Maltose-binding protein | Maltose | Gene expression | Autocatalysis | Muscle contraction | Physics | Medicine | Ribosomal protein S6 kinase | Signaling | Insects | Protein kinase | Isoforms | Homogeneity | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article