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Epilepsy Research, ISSN 0920-1211, 09/2019, p. 106211
Journal Article
The Lancet, ISSN 0140-6736, 03/2018, Volume 391, Issue 10125, pp. 1085 - 1096
Patients with Lennox-Gastaut syndrome, a rare, severe form of epileptic encephalopathy, are frequently treatment resistant to available medications. No... 
VAGUS NERVE-STIMULATION | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | CONSENSUS APPROACH | EFFICACY | TOLERABILITY | CLOBAZAM | EXPERIENCE | EPILEPSY | RUFINAMIDE | CHILDREN | Young adults | Epilepsy | Childrens health | Clinical trials | Alcohol | Electroencephalography | Drug resistance | Evidence-based medicine | Neurology | Convulsions & seizures | Diet | Marijuana | Age | Seizures | Pharmaceuticals
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2015, Volume 56, Issue 2, pp. 441 - 444
[Display omitted] This work presents a new synthesis of the antiepileptic drug rufinamide—1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide) in chemical... 
Trichloroacetylated enolethers | 1,3-Dipolar cycloaddition | Rufinamide | 1H-1,2,3-triazoles | Benzyl azides | Rufinamide 1H-1,2,3-triazoles | Benzyl azides 1,3-Dipolar cycloaddition | CYCLOADDITION | CHEMISTRY, ORGANIC | Drugs | Synthesis (chemistry) | Aqueous solutions | Precursors | Analogue | Tetrahedrons | Amides | Catalysis
Journal Article
Australian prescriber, ISSN 0312-8008, 02/2019, Volume 42, Issue 1, pp. 38 - 39
Journal Article
Journal of Pediatric Epilepsy, ISSN 2146-457X, 2012, Volume 1, Issue 2, pp. 97 - 101
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2017, Volume 58, Issue 40, pp. 3827 - 3830
[Display omitted] •A rapid assessment for carbohydrazides analogues to rufinamide is presented.•Oxadiazoles, pyrrole and pyrazoline derivatives are obtained by... 
Carbohydrazides | Cyclocondensation reactions | Rufinamide | Triazoles | Haloformic reactions | Real property | Valuation | Analysis | Schiff bases | Derivatives (Financial instruments)
Journal Article
European Journal of Paediatric Neurology, ISSN 1090-3798, 01/2019, Volume 23, Issue 1, pp. 126 - 135
Evaluate the long-term safety, tolerability, and behavioral effects of adjunctive rufinamide in pediatric patients (≥1 to <4 years old) with inadequately... 
Antiepileptic drug | Neurodevelopment | Behavior | Children | Rufinamide | Epilepsy | DIAGNOSIS | MULTICENTER | PEDIATRICS | CLINICAL NEUROLOGY
Journal Article
Epileptic Disorders, ISSN 1294-9361, 02/2018, Volume 20, Issue 1, pp. 13 - 29
Journal Article
Epilepsia, ISSN 0013-9580, 08/2014, Volume 55, Issue 8, pp. 1235 - 1244
Journal Article
ACS Catalysis, ISSN 2155-5435, 06/2014, Volume 4, Issue 6, pp. 1901 - 1910
Several rhodium­(I) complexes, [RhCl­(COD)­(PR3)], containing potentially cooperative phosphine ligands, have been synthesized and evaluated as catalysts for... 
aminophosphines | amides | nitriles | hydration reactions | rufinamide | aqueous catalysis | rhodium complexes | ACTIVATION | SELECTIVE HYDRATION | LIGAND SUBSTITUTION | AQUEOUS-MEDIUM | CHEMISTRY, PHYSICAL | PHOSPHINE-LIGANDS | ORGANOMETALLIC CHEMISTRY | EFFICIENT | CYANOHYDRIN HYDRATION
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 05/2018, Volume 59, Issue 18, pp. 1760 - 1762
[Display omitted] •Facile synthesis of Rufinamide analogues.•Azide-enolate cycloaddition as versatile tool.•β-ketonitriles as eficient dipolarophiles. The... 
1,2,3-Triazoles | β-Ketonitriles | Rufinamide analogs | Azide-enolate cycloaddition | 1,3-DIPOLAR CYCLOADDITION | beta-Ketonitriles | CHEMISTRY, ORGANIC | ANTIEPILEPTIC DRUG | HYDRATION | FLOW | ALKYNE CYCLOADDITION | SOLVENTLESS
Journal Article
Analytical Chemistry Letters, ISSN 2229-7928, 05/2018, Volume 8, Issue 3, pp. 405 - 415
Rufinamide is a triazole derivative used as an anticonvulsant was subjected to stress degradation under various stress conditions of hydrolysis, oxidation,... 
LC/QTOF/MS/MS | IR | NMR | Rufinamide | degradation products
Journal Article
Therapeutic drug monitoring, ISSN 0163-4356, 04/2019, Volume 41, Issue 2, pp. 168 - 173
Epilepsy is characterized by seizures recurring at interindividually differing time intervals. It may be difficult to assess drug response if time intervals... 
epilepsy | DEFINITION | antiepileptic drugs | EVEROLIMUS | ILAE COMMISSION | biomarkers | EEG | CLINICAL PHARMACOKINETICS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MEDICAL LABORATORY TECHNOLOGY | RUFINAMIDE | therapeutic drug monitoring | pharmacogenetics | RAPID DETECTION | ADVERSE EVENTS | ONSET | Drug metabolism | Pharmacology, Experimental | Models | Drug therapy | Epilepsy
Journal Article
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