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life sciences & biomedicine (7) 7
science & technology (7) 7
rxrα (5) 5
cholestasis (4) 4
gastroenterology & hepatology (4) 4
humans (4) 4
gastroenterology and hepatology (3) 3
ae2, anion exchanger 2 (2) 2
animals (2) 2
beta (2) 2
bile acids and salts - metabolism (2) 2
bsep, bile salt export pump (2) 2
car (2) 2
fxr, farnesoid x receptor (2) 2
gene expression (2) 2
gr, glucocorticoid receptor (2) 2
hnf1α, hepatocyte nuclear factor 1 alpha (2) 2
hnf4α, hepatocyte nuclear factor 4 alpha (2) 2
icp, intrahepatic cholestasis of pregnancy (2) 2
inflammation (2) 2
liver (2) 2
liver - metabolism (2) 2
liver regeneration - physiology (2) 2
nuclear receptor (2) 2
nuclear receptors (2) 2
pbc, primary biliary cirrhosis (2) 2
pparα, peroxisome proliferator-activated receptor alpha (2) 2
pparγ, peroxisome proliferator-activated receptor gamma (2) 2
psc, primary sclerosing cholangitis (2) 2
pxr, pregnane x receptor (2) 2
receptors, cytoplasmic and nuclear - genetics (2) 2
retinoid x receptor alpha - genetics (2) 2
review (2) 2
shp, short heterodimer partner (2) 2
tpn, total parenteral nutrition (2) 2
udca, ursodeoxycholic acid (2) 2
15 (1) 1
19, fibroblast growth factor 15 (1) 1
3 (1) 1
6-ecdca, 6-ethylchenodeoxycholic acid (1) 1
8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5 (1) 1
abbreviations (1) 1
abc, atp-binding cassette (1) 1
abcg5 (1) 1
abcg5/8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5/8 (1) 1
agriculture (1) 1
agriculture, dairy & animal science (1) 1
alfacalcidol (1) 1
alp, alkaline phosphatase (1) 1
alt, alanine aminotransferase (1) 1
ampk, amp activated protein kinase (1) 1
ampk, amp-activated protein kinase (1) 1
androgen receptor (1) 1
animal models (1) 1
ar (1) 1
asbt, apical sodium-dependent bile acid transporter (1) 1
ascom, activating signal cointegrator-2-containing complex (1) 1
asian continental ancestry group - genetics (1) 1
asians (1) 1
atb-binding cassette transporters (1) 1
atp binding cassette subfamily b member 11 (1) 1
atp-binding cassette transporters - genetics (1) 1
atp-binding cassette transporters - metabolism (1) 1
ba (1) 1
ba, bile acid (1) 1
bcrp, breast cancer resistance protein (1) 1
bcrp, breast cancer resistance protein, atp-binding cassette, subfamily g, member 2 (1) 1
bile acid (1) 1
bile acid receptor (1) 1
bile acids (1) 1
bile acids, cholestasis, fatty liver disease, gallstones, liver regeneration, liver cancer (1) 1
biochemistry (1) 1
biochemistry & molecular biology (1) 1
biological and medical sciences (1) 1
biological transport (1) 1
biotechnology & applied microbiology (1) 1
bric, benign recurrent intrahepatic cholestasis (1) 1
bric2, benign recurrent intrahepatic cholestasis type 2 (1) 1
bs, bile salt (1) 1
ca, cholic acid (1) 1
calcifediol (1) 1
camp, cyclic adenosine monophosphate (1) 1
car, constitutive androstane receptor (1) 1
carm1, co-activator-associated arginine methyltransferase 1 (1) 1
carrier proteins - metabolism (1) 1
cbdl, common bile duct ligation (1) 1
ccl4, carbone tetrachloride (1) 1
cdca, chenodeoxycholic acid (1) 1
cell nucleus - drug effects (1) 1
cell nucleus - genetics (1) 1
cell nucleus - metabolism (1) 1
cholestasis - genetics (1) 1
cholestasis - metabolism (1) 1
cholestasis - pathology (1) 1
cholestasis - therapy (1) 1
chromatin (1) 1
clinical biochemistry (1) 1
constitutive androstane receptor (1) 1
corticosteroids (1) 1
ctbp, c-terminal binding protein (1) 1
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Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Molecular aspects of medicine, ISSN 0098-2997, 06/2014, Volume 37, Issue 100, pp. 57 - 76
Nuclear receptors | ATB-binding cassette transporters | Cholestasis | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cholestasis - genetics | Transcriptional Activation - genetics | Cholestasis - therapy | Humans | Gene Expression Regulation | Bile Acids and Salts - metabolism | Symporters - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Cholestasis - pathology | ATP-Binding Cassette Transporters - genetics | Biological Transport | ATP Binding Cassette Subfamily B Member 11 | Membrane Transport Proteins - genetics | Symporters - genetics | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Genetic aspects | Genetic transcription | Index Medicus | MAF, musculo-aponeurotic fibrosacroma | TNF-α, tumor necrosis factor alpha | NDRG2, NMYC downstrean-regulated gene 2 | RARα (NR1B1), retinoic acid receptor | IL-6, interleukin 6 | ABC, ATP-binding cassette | DCA, deoxycholic acid | GGT, gamma-glutamyl transpeptidase | CARM1, co-activator-associated arginine methyltransferase 1 | SRC2, steroid receptor co-activator 2 | TCDCA, taurochenodeoxycholic acid | MRP2 (ABCC2), multidrug resistance-associated protein 2 | SREBP1, sterol regulatory element-binding protein 1 | ASBT (SLC10A2), apical sodium-dependent bile acid transporter | CA, cholic acid | UDCA, ursodeoxycholic acid | FGF15, fibroblast growth factor 19 | MARE, MAF recognition element | TβMCA, β-tauromuricholic acid | VDR (NR1I1), vitamin D receptor | CBDL, common bile duct ligation | STAT-5, signal transducer and activator of transcription 5 | MCL-1, myeloid cell leukemia factor 1 | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | FXRE, FXR response element | LXR (NR1H3), liver X receptor | CtBP, C-terminal binding protein | 15 | OSTβ (SLC51A | SHP (NR0B2), short heterodimer partner | PL, phospholipid | BCRP (ABCG2), breast cancer resistance protein | TUDCA, tauroursodeoxycholic acid | OATP, organic anion transporting polypeptide | TCA, taurocholic acid | NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1 | PSC, primary sclerosing cholangitis | LRH1 (NR5A2), liver receptor homologue 1 | LPS, lipopolysaccharide | MRP3 (ABCC3), multidrug resistance-associated protein 3 | SLC51B), organic solute transporter alpha | TGR5, G protein coupled bile acid receptor | MDR2 (ABCB4), multidrug resistance protein 2 | FXR, farnesoid X receptor (NR1H4) | IR-1, inverse repeat 1 | OCA, obeticholic acid | MRP4 (ABCC4), multidrug resistance-associated protein 4 | AE2 (SLC4A2), anion exchanger 2 | NF-κB, nuclear factor kappa-B | CCl4, carbone tetrachloride | AMPK, AMP-activated protein kinase | ALP, alkaline phosphatase | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | DILI, drug-induced liver injury | JNK, c-Jun N-terminal kinase | GR (NR3C1), glucocorticoid receptor | BS, bile salt | IL-1β, interleukin-1 beta | cAMP, cyclic adenosine monophosphate | PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha | RXRα (NR2B1), retinoid X receptor | VPAC-1, vasoactive intestinal polypeptide activated receptor | ASCOM, activating signal cointegrator-2-containing complex | ICP, intrahepatic cholestasis of pregnancy | GCA, glycocholic acid | MDR1 (ABCB1), multidrug resistance protein 1 | NRF2, nuclear factor erythroid 2-related factor 2 | beta | ALT, alanine aminotransferase | LCA, litocholic acid | BRIC2, benign recurrent intrahepatic cholestasis type 2 | OSTα | CDCA, chenodeoxycholic acid | PBC, primary biliary cirrhosis | HNF1α, hepatocyte nuclear factor 1 alpha | GRE, glucocorticoid response element | TαMCA, α-tauromuricholic acid | FGF19 | PFIC2, progressive familial intrahepatic cholestasis type 2 | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | TPN, total parenteral nutrition | HNF4α, hepatocyte nuclear factor 4 alpha
Journal Article
Journal of hepatology, ISSN 0168-8278, 2009, Volume 52, Issue 3, pp. 455 - 462
Gastroenterology and Hepatology | Nuclear receptor | Fatty liver | Gene expression | Ligand | Cholestasis | Fibrosis | HNF | glucocorticoid receptor | GWAS | hepatitis B virus | AR (NR3C4) | MTP | nuclear (hormone) receptor | double knockout | pregnane X receptor | VDR (NR1I2) | PBC | androgen receptor | fibroblast growth factor | RARα (NR1B1) | primary biliary cirrhosis | HSC | vitamin D receptor | Abbreviations | HBV | hepatocellular carcinoma | hepatocyte nuclear factor | retinoid X receptor | GR (NR3C1) | PSC | hepatic stellate cells | peroxisomal proliferator-activated receptor gamma | LRH-1 (NR5A2) | FGF | bile acid | DKO | HCC | CAR (NR1I3) | non alcoholic fatty liver disease | SHP (NR0B2) | HCV | FA | peroxisomal proliferator-activated receptor alpha | primary sclerosing cholangitis | BA | NAFLD | NR | white adipose tissue | fatty acid | PPARα (NR1C1) | WAT | hepatitis C virus | genome wide association study | farnesoid X receptor/bile acid receptor | liver receptor homolog-1 | microsomal transfer protein | estrogen receptor | RXRα (NR2B1) | intrahepatic cholestasis of pregnancy | retinoic acid receptor | PPARγ (NR1C3) | PXR (NR1I2) | ER (NR3A1) | constitutive androstane receptor | ICP | short heterodimer partner | FXR (NR1H4) | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Transcription Factors - physiology | Inactivation, Metabolic - physiology | Polymorphism, Genetic - physiology | Humans | Liver - physiology | Liver Diseases - therapy | Receptors, Cytoplasmic and Nuclear - physiology | Receptors, Cytoplasmic and Nuclear - genetics | Liver Diseases - physiopathology | Liver Regeneration - physiology | Lipid Metabolism - physiology | Inflammation - physiopathology | Index Medicus
Journal Article