Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
life sciences & biomedicine (7) 7
science & technology (7) 7
rxrα (5) 5
cholestasis (4) 4
gastroenterology & hepatology (4) 4
humans (4) 4
gastroenterology and hepatology (3) 3
ae2, anion exchanger 2 (2) 2
animals (2) 2
beta (2) 2
bile acids and salts - metabolism (2) 2
bsep, bile salt export pump (2) 2
car (2) 2
fxr, farnesoid x receptor (2) 2
gene expression (2) 2
gr, glucocorticoid receptor (2) 2
hnf1α, hepatocyte nuclear factor 1 alpha (2) 2
hnf4α, hepatocyte nuclear factor 4 alpha (2) 2
icp, intrahepatic cholestasis of pregnancy (2) 2
inflammation (2) 2
liver (2) 2
liver - metabolism (2) 2
liver regeneration - physiology (2) 2
nuclear receptor (2) 2
nuclear receptors (2) 2
pbc, primary biliary cirrhosis (2) 2
pparα, peroxisome proliferator-activated receptor alpha (2) 2
pparγ, peroxisome proliferator-activated receptor gamma (2) 2
psc, primary sclerosing cholangitis (2) 2
pxr, pregnane x receptor (2) 2
receptors, cytoplasmic and nuclear - genetics (2) 2
retinoid x receptor alpha - genetics (2) 2
review (2) 2
shp, short heterodimer partner (2) 2
tpn, total parenteral nutrition (2) 2
udca, ursodeoxycholic acid (2) 2
15 (1) 1
19, fibroblast growth factor 15 (1) 1
3 (1) 1
6-ecdca, 6-ethylchenodeoxycholic acid (1) 1
8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5 (1) 1
abbreviations (1) 1
abc, atp-binding cassette (1) 1
abcg5 (1) 1
abcg5/8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5/8 (1) 1
agriculture (1) 1
agriculture, dairy & animal science (1) 1
alfacalcidol (1) 1
alp, alkaline phosphatase (1) 1
alt, alanine aminotransferase (1) 1
ampk, amp activated protein kinase (1) 1
ampk, amp-activated protein kinase (1) 1
androgen receptor (1) 1
animal models (1) 1
ar (1) 1
asbt, apical sodium-dependent bile acid transporter (1) 1
ascom, activating signal cointegrator-2-containing complex (1) 1
asian continental ancestry group - genetics (1) 1
asians (1) 1
atb-binding cassette transporters (1) 1
atp binding cassette subfamily b member 11 (1) 1
atp-binding cassette transporters - genetics (1) 1
atp-binding cassette transporters - metabolism (1) 1
ba (1) 1
ba, bile acid (1) 1
bcrp, breast cancer resistance protein (1) 1
bcrp, breast cancer resistance protein, atp-binding cassette, subfamily g, member 2 (1) 1
bile acid (1) 1
bile acid receptor (1) 1
bile acids (1) 1
bile acids, cholestasis, fatty liver disease, gallstones, liver regeneration, liver cancer (1) 1
biochemistry (1) 1
biochemistry & molecular biology (1) 1
biological and medical sciences (1) 1
biological transport (1) 1
biotechnology & applied microbiology (1) 1
bric, benign recurrent intrahepatic cholestasis (1) 1
bric2, benign recurrent intrahepatic cholestasis type 2 (1) 1
bs, bile salt (1) 1
ca, cholic acid (1) 1
calcifediol (1) 1
camp, cyclic adenosine monophosphate (1) 1
car, constitutive androstane receptor (1) 1
carm1, co-activator-associated arginine methyltransferase 1 (1) 1
carrier proteins - metabolism (1) 1
cbdl, common bile duct ligation (1) 1
ccl4, carbone tetrachloride (1) 1
cdca, chenodeoxycholic acid (1) 1
cell nucleus - drug effects (1) 1
cell nucleus - genetics (1) 1
cell nucleus - metabolism (1) 1
cholestasis - genetics (1) 1
cholestasis - metabolism (1) 1
cholestasis - pathology (1) 1
cholestasis - therapy (1) 1
chromatin (1) 1
clinical biochemistry (1) 1
constitutive androstane receptor (1) 1
corticosteroids (1) 1
ctbp, c-terminal binding protein (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Bile acid transporters and regulatory nuclear receptors in the liver and beyond
by Halilbasic, Emina and Claudel, Thierry and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Genetic Variations of NR1I3 and NR2B1 in Asian Populations
by Chew, Sin Chi and Lim, Joanne Siok Liu and Singh, Onkar and Wong, Mabel and Lee, Edmund J.D and Chowbay, Balram and Department of Medical Oncology and Division of Medical Sciences and Department of Pharmacology and Office of Clinical Sciences and Duke-NUS Graduate Medical School Singapore and Yong Loo Lin School of Medicine and National Cancer Centre and Laboratory of Clinical Pharmacology and Humphrey Oei Institute of Cancer Research and National University of Singapore
Drug metabolism and pharmacokinetics, ISSN 1347-4367, 2013, Volume 28, Issue 2, pp. 169 - 176
RXRα | CAR | NR1I3 | in-silieo prediction | tag-SNPs | NR2B1 | polymorphisms | pharmacogenetics | Asians | in-silico prediction | Pharmacogenetics | Tag-SNPs | In-silico prediction | Polymorphisms | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Gene Frequency - genetics | Introns - genetics | Humans | Asian Continental Ancestry Group - genetics | Retinoid X Receptor alpha - genetics | Linkage Disequilibrium - genetics | Polymorphism, Single Nucleotide - genetics | Exons - genetics | Genetic Variation - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Clinical application of transcriptional activators of bile salt transporters
by Baghdasaryan, Anna and Chiba, Peter and Trauner, Michael
Molecular aspects of medicine, ISSN 0098-2997, 06/2014, Volume 37, Issue 100, pp. 57 - 76
Nuclear receptors | ATB-binding cassette transporters | Cholestasis | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cholestasis - genetics | Transcriptional Activation - genetics | Cholestasis - therapy | Humans | Gene Expression Regulation | Bile Acids and Salts - metabolism | Symporters - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Cholestasis - pathology | ATP-Binding Cassette Transporters - genetics | Biological Transport | ATP Binding Cassette Subfamily B Member 11 | Membrane Transport Proteins - genetics | Symporters - genetics | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Genetic aspects | Genetic transcription | Index Medicus | MAF, musculo-aponeurotic fibrosacroma | TNF-α, tumor necrosis factor alpha | NDRG2, NMYC downstrean-regulated gene 2 | RARα (NR1B1), retinoic acid receptor | IL-6, interleukin 6 | ABC, ATP-binding cassette | DCA, deoxycholic acid | GGT, gamma-glutamyl transpeptidase | CARM1, co-activator-associated arginine methyltransferase 1 | SRC2, steroid receptor co-activator 2 | TCDCA, taurochenodeoxycholic acid | MRP2 (ABCC2), multidrug resistance-associated protein 2 | SREBP1, sterol regulatory element-binding protein 1 | ASBT (SLC10A2), apical sodium-dependent bile acid transporter | CA, cholic acid | UDCA, ursodeoxycholic acid | FGF15, fibroblast growth factor 19 | MARE, MAF recognition element | TβMCA, β-tauromuricholic acid | VDR (NR1I1), vitamin D receptor | CBDL, common bile duct ligation | STAT-5, signal transducer and activator of transcription 5 | MCL-1, myeloid cell leukemia factor 1 | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | FXRE, FXR response element | LXR (NR1H3), liver X receptor | CtBP, C-terminal binding protein | 15 | OSTβ (SLC51A | SHP (NR0B2), short heterodimer partner | PL, phospholipid | BCRP (ABCG2), breast cancer resistance protein | TUDCA, tauroursodeoxycholic acid | OATP, organic anion transporting polypeptide | TCA, taurocholic acid | NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1 | PSC, primary sclerosing cholangitis | LRH1 (NR5A2), liver receptor homologue 1 | LPS, lipopolysaccharide | MRP3 (ABCC3), multidrug resistance-associated protein 3 | SLC51B), organic solute transporter alpha | TGR5, G protein coupled bile acid receptor | MDR2 (ABCB4), multidrug resistance protein 2 | FXR, farnesoid X receptor (NR1H4) | IR-1, inverse repeat 1 | OCA, obeticholic acid | MRP4 (ABCC4), multidrug resistance-associated protein 4 | AE2 (SLC4A2), anion exchanger 2 | NF-κB, nuclear factor kappa-B | CCl4, carbone tetrachloride | AMPK, AMP-activated protein kinase | ALP, alkaline phosphatase | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | DILI, drug-induced liver injury | JNK, c-Jun N-terminal kinase | GR (NR3C1), glucocorticoid receptor | BS, bile salt | IL-1β, interleukin-1 beta | cAMP, cyclic adenosine monophosphate | PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha | RXRα (NR2B1), retinoid X receptor | VPAC-1, vasoactive intestinal polypeptide activated receptor | ASCOM, activating signal cointegrator-2-containing complex | ICP, intrahepatic cholestasis of pregnancy | GCA, glycocholic acid | MDR1 (ABCB1), multidrug resistance protein 1 | NRF2, nuclear factor erythroid 2-related factor 2 | beta | ALT, alanine aminotransferase | LCA, litocholic acid | BRIC2, benign recurrent intrahepatic cholestasis type 2 | OSTα | CDCA, chenodeoxycholic acid | PBC, primary biliary cirrhosis | HNF1α, hepatocyte nuclear factor 1 alpha | GRE, glucocorticoid response element | TαMCA, α-tauromuricholic acid | FGF19 | PFIC2, progressive familial intrahepatic cholestasis type 2 | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | TPN, total parenteral nutrition | HNF4α, hepatocyte nuclear factor 4 alpha
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The new therapeutic frontier – Nuclear receptors and the liver
by Karpen, Saul J and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2009, Volume 52, Issue 3, pp. 455 - 462
Gastroenterology and Hepatology | Nuclear receptor | Fatty liver | Gene expression | Ligand | Cholestasis | Fibrosis | HNF | glucocorticoid receptor | GWAS | hepatitis B virus | AR (NR3C4) | MTP | nuclear (hormone) receptor | double knockout | pregnane X receptor | VDR (NR1I2) | PBC | androgen receptor | fibroblast growth factor | RARα (NR1B1) | primary biliary cirrhosis | HSC | vitamin D receptor | Abbreviations | HBV | hepatocellular carcinoma | hepatocyte nuclear factor | retinoid X receptor | GR (NR3C1) | PSC | hepatic stellate cells | peroxisomal proliferator-activated receptor gamma | LRH-1 (NR5A2) | FGF | bile acid | DKO | HCC | CAR (NR1I3) | non alcoholic fatty liver disease | SHP (NR0B2) | HCV | FA | peroxisomal proliferator-activated receptor alpha | primary sclerosing cholangitis | BA | NAFLD | NR | white adipose tissue | fatty acid | PPARα (NR1C1) | WAT | hepatitis C virus | genome wide association study | farnesoid X receptor/bile acid receptor | liver receptor homolog-1 | microsomal transfer protein | estrogen receptor | RXRα (NR2B1) | intrahepatic cholestasis of pregnancy | retinoic acid receptor | PPARγ (NR1C3) | PXR (NR1I2) | ER (NR3A1) | constitutive androstane receptor | ICP | short heterodimer partner | FXR (NR1H4) | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Transcription Factors - physiology | Inactivation, Metabolic - physiology | Polymorphism, Genetic - physiology | Humans | Liver - physiology | Liver Diseases - therapy | Receptors, Cytoplasmic and Nuclear - physiology | Receptors, Cytoplasmic and Nuclear - genetics | Liver Diseases - physiopathology | Liver Regeneration - physiology | Lipid Metabolism - physiology | Inflammation - physiopathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights