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International Journal of Molecular Sciences, ISSN 1661-6596, 08/2018, Volume 19, Issue 8, p. 2354
Journal Article
Cancer Research, ISSN 0008-5472, 08/2014, Volume 74, Issue 16, pp. 4364 - 4377
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2019, Volume 176, Issue 14, pp. 2559 - 2572
Background and Purpose Atherosclerosis is a chronic inflammatory disease, and retinoid X receptor‐α (RXRα) is an intriguing anti‐atherosclerosis target. This... 
DESIGN | INHIBITION | CONCISE GUIDE | INFLAMMATION | IKK-BETA | PHARMACOLOGY & PHARMACY | AUTOPHAGY | NF-KAPPA-B | P62 | BINDING | RXR-ALPHA | Translocation | Fluctuations | Transcription | Flux | Lipids | Macrophages | Autophagy | Arteries | Nuclear transport | Carotid arteries | Inflammatory diseases | Apolipoprotein E | Arteriosclerosis | Sulindac | Atherosclerosis | Inhibition | Carotid artery | Lesions | RelA protein | Localization | Destabilization | Phagocytosis
Journal Article
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 04/2019, Volume 31, Issue 4, pp. 251 - 262
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is an intractable disease of the gastrointestinal tract. Multiple... 
DEXTRAN SULFATE SODIUM | monocytes | ACTIVATION | Nur77 | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | RXR | inflammatory bowel disease | INFLAMMATORY-BOWEL-DISEASE | PPAR | DOCOSAHEXAENOIC ACID | POLYUNSATURATED FATTY-ACIDS | BEXAROTENE | TNF-ALPHA | NF-KAPPA-B | EXPRESSION
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 44, pp. 30538 - 30555
Previous data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and insoluble amyloid-beta (A beta) in Alzheimer disease... 
BEXAROTENE THERAPY | ABCA1 | ALZHEIMERS-DISEASE | DEPOSITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | A-BETA | TRANSGENIC MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | BRAIN | APOLIPOPROTEIN-E | Disks Large Homolog 4 Protein | Liver - pathology | Nicotinic Acids - pharmacokinetics | Humans | Male | Tetrahydronaphthalenes - adverse effects | ATP Binding Cassette Transporter 1 - metabolism | Liver - drug effects | Tetrahydronaphthalenes - administration & dosage | Amyloid beta-Peptides - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Membrane Proteins - metabolism | Nicotinic Acids - administration & dosage | Drug Evaluation, Preclinical | Nicotinic Acids - adverse effects | Retinoid X Receptors - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Bexarotene | Peptide Fragments - metabolism | Administration, Oral | Mice, Inbred C57BL | Solubility | Alzheimer Disease - drug therapy | Tetrahydronaphthalenes - pharmacokinetics | Genotype | Mice, Transgenic | Organ Size - drug effects | Animals | Retinoid X Receptors - agonists | Apolipoproteins E - genetics | Guanylate Kinases - metabolism | Index Medicus | Molecular Bases of Disease | Oligomeric Aβ | Alzheimer Disease | Drug Delivery | Aβ Complex | Apolipoprotein E (ApoE) | Amyloid-β (AB) | RXR Agonists | Hepatomegaly | ABCG1 Lipid Transporters | Drug Action | ApoE
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 12/2016, Volume 17, Issue 6, pp. 742 - 767
Since the isolation and identification of the retinoid X receptor (RXR) as a member of the nuclear receptor (NR) superfamily in 1990, its analysis has ushered... 
Organic synthesis | Ligand | RXR | Rexinoid | Retinoid | CHEMISTRY, MEDICINAL | ORPHAN NUCLEAR RECEPTORS | THYROID-HORMONE | RXR HETERODIMERS | VITAMIN-D-RECEPTOR | CELL LUNG-CANCER | ACID-RECEPTOR | DOCOSAHEXAENOIC ACID | BIOLOGICAL EVALUATION | PPAR-GAMMA | LIGAND-BINDING DOMAIN
Journal Article