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Radiation Research, ISSN 0033-7587, 2010, Volume 173, Issue 6, pp. 719 - 728
Journal Article
Redox Biology, ISSN 2213-2317, 12/2015, Volume 6, pp. 1 - 8
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, pp. 31973 - 31973
Ruthenium(II) polypyridyl complexes can intercalate DNA with high affinity and prevent cell proliferation; however, the direct impact of ruthenium-based... 
APOPTOSIS | DAMAGE RESPONSE | THERAPY | ANTICANCER | MULTIDISCIPLINARY SCIENCES | METALLO-INTERCALATORS | IN-VIVO | COMPLEXES | CYCLE ARREST | CYTOTOXICITY | CELLULAR UPTAKE | Gene Expression - drug effects | Apoptosis - drug effects | Apoptosis - radiation effects | DNA Replication - drug effects | Humans | Coordination Complexes - metabolism | Ruthenium - chemistry | Cattle | BRCA1 Protein - metabolism | Radiation-Sensitizing Agents - chemistry | Phosphorylation - drug effects | Quinolines - toxicity | Radiation-Sensitizing Agents - toxicity | Coordination Complexes - toxicity | Quinuclidines - toxicity | Radiation, Ionizing | DNA Damage - drug effects | Cell Line | DNA Repair - drug effects | Checkpoint Kinase 1 - antagonists & inhibitors | DNA - metabolism | Coordination Complexes - chemistry | Gene Expression - radiation effects | Intercalating Agents - chemistry | BRCA1 Protein - genetics | Checkpoint Kinase 1 - metabolism | Intercalating Agents - metabolism | Animals | Intercalating Agents - toxicity | Radiation-Sensitizing Agents - metabolism | Cell Proliferation - drug effects | HeLa Cells | Histones - metabolism | G1 Phase Cell Cycle Checkpoints - drug effects | DNA Damage - radiation effects | Cell proliferation | Cell survival | Histone H2A | Epithelial cells | CHK1 protein | DNA damage | Cervix | Intercalation | Replication forks | DNA biosynthesis | Cell growth | Cervical cancer | Deoxyribonucleic acid--DNA | Cancer | Apoptosis | Index Medicus
Journal Article
Trends in Biotechnology, ISSN 0167-7799, 2003, Volume 21, Issue 5, pp. 210 - 216
The carotenoid pigment astaxanthin has important applications in the nutraceutical, cosmetics, food and feed industries. Haematococcus pluvialis is the richest... 
BETA-CAROTENE | OXIDATIVE STRESS | IMMUNOMODULATING ACTIONS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NATURALLY-OCCURRING XANTHOPHYLLS | T-DEPENDENT ANTIGENS | MACULAR DEGENERATION | DIETARY ANTIOXIDANTS | CORONARY HEART-DISEASE | VITRO ANTIBODY-PRODUCTION | VITAMIN-A | Neurodegenerative Diseases - diet therapy | Xanthophylls | Species Specificity | Antioxidants - metabolism | Humans | Nutritional Physiological Phenomena | Biological Availability | beta Carotene - pharmacokinetics | Radiation-Sensitizing Agents - pharmacokinetics | Blindness - prevention & control | Chlorophyta - metabolism | Adjuvants, Immunologic - pharmacokinetics | Radiation-Sensitizing Agents - therapeutic use | Inflammation - diet therapy | Radiation-Sensitizing Agents - administration & dosage | Adjuvants, Immunologic - metabolism | Adjuvants, Immunologic - therapeutic use | Chlorophyta - classification | Macular Degeneration - prevention & control | Administration, Oral | beta Carotene - administration & dosage | beta Carotene - metabolism | Chlorophyta - chemistry | Antioxidants - therapeutic use | Arteriosclerosis - prevention & control | Neoplasms - diet therapy | Photosensitivity Disorders - prevention & control | Radiation-Sensitizing Agents - metabolism | Antioxidants - administration & dosage | Diet Therapy - methods | Antioxidants - pharmacokinetics | beta Carotene - analogs & derivatives | Macular degeneration | Antioxidants | Aging | Lipids | Fish
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e107158
Photodynamic therapy (PDT) has emerged as an effective treatment for various solid tumors. The transcription factor NRF2 is known to protect against oxidative... 
APOPTOSIS | IN-VITRO | PROTEIN | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | RESISTANCE | KEAP1-NRF2 PATHWAY | DEATH | HUMAN HEPATOCELLULAR-CARCINOMA | IDENTIFICATION | SCUTELLARIA-BARBATA | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Neoplasms - metabolism | RNA, Small Interfering - genetics | Colonic Neoplasms - genetics | Reactive Oxygen Species - metabolism | Humans | Laser Therapy | Chlorophyll - analogs & derivatives | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Photochemotherapy | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Chlorophyll - administration & dosage | Gene Knockdown Techniques | Radiation-Sensitizing Agents - administration & dosage | Neoplasms - genetics | Lasers | ATP-Binding Cassette Transporters - metabolism | Female | Lentivirus - genetics | NF-E2-Related Factor 2 - genetics | Radiation-Sensitizing Agents - toxicity | Chlorophyll - toxicity | Transduction, Genetic | Gene Silencing | Chlorophyll - metabolism | Genetic Vectors - genetics | Neoplasms - drug therapy | Breast Neoplasms - genetics | Radiation-Sensitizing Agents - metabolism | Cell Line, Tumor | Peroxiredoxin III - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | RNA, Small Interfering - metabolism | Drugs | Peroxiredoxin | Toxicity | Glioblastoma | Cytotoxicity | Confocal | Drug resistance | Kinases | Breast carcinoma | Mitochondria | Rodents | Colon | Oxygen | Photodynamic therapy | Incubation | Breast cancer | Low level | Signaling | Sensitivity | Singlet oxygen | Cell death | Cell lines | Breast | Sensitivity enhancement | Solid tumors | Clear cell-type renal cell carcinoma | Tumors | Cancer | Apoptosis
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 358, Issue 2, pp. 107 - 114
Highlights • IL-21 is mainly produced by CD4+ T cells and natural killer T (NKT) cells. • IL-21 is a new member of the common γ-chain family of cytokines. •... 
Hematology, Oncology and Palliative Medicine | IL-21 | Immune response | Cancer | NATURAL-KILLER-CELL | B-CELL DIFFERENTIATION | HOMEOSTATIC PROLIFERATION | CD8(+) T-CELLS | CUTTING EDGE | LIVER-CANCER | METASTATIC MELANOMA | STAT3 ACTIVATION | HUMAN NAIVE | ONCOLOGY | PHASE-I | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | Germinal Center - immunology | Humans | Receptors, Interleukin-21 - genetics | Immunity | Interleukins - metabolism | Neoplasms - therapy | Neoplasms - genetics | Immunotherapy | Killer Cells, Natural - immunology | Plasma Cells - metabolism | Cell Differentiation | B-Lymphocytes - metabolism | B-Lymphocytes - cytology | Gene Expression | Signal Transduction | Lymphocyte Activation | Cell Communication | Receptors, Interleukin-21 - metabolism | Radiotherapy | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | Radiation-Sensitizing Agents - metabolism | Antibody Formation | Immunologic Memory | Neovascularization, Pathologic - metabolism | Killer Cells, Natural - metabolism | Neoplasms - pathology | Plasma Cells - cytology | Apoptosis | Plasma Cells - immunology | Development and progression | Pathogenesis | Interleukin | Cytotoxicity | Lymphocytes T | Cancer therapies | Inflammatory diseases | Angiogenesis | Cell growth | Immunology | Lymphocytes | Interleukin 21 | Natural killer cells | Antigens | Cytokines | T cell receptors | Radiation therapy | Bladder cancer | Allergies | CD4 antigen | Studies | Mutation | Autoimmune diseases | Tumors
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2012, Volume 425, Issue 2, pp. 393 - 397
Journal Article
Journal of Physical Chemistry B, ISSN 1520-6106, 06/2014, Volume 118, Issue 23, pp. 6159 - 6166
Journal Article
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2015, Volume 92, Issue 5, pp. 986 - 992
Purpose Valproic acid (VPA) is an antiepileptic agent with histone deacetylase inhibitor (HDACi) activity shown to sensitize glioblastoma (GBM) cells to... 
Radiology | Hematology, Oncology and Palliative Medicine | PLUS TEMOZOLOMIDE | MALIGNANT GLIOMA | SURVIVAL | ONCOLOGY | NEWLY-DIAGNOSED GLIOBLASTOMA | CONCOMITANT | RANDOMIZED-TRIAL | RADIOTHERAPY | MULTIFORME | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ERLOTINIB | ADJUVANT TEMOZOLOMIDE | Multivariate Analysis | Dacarbazine - adverse effects | Age Factors | Dacarbazine - therapeutic use | Humans | Middle Aged | Male | Bone Marrow - radiation effects | Glioblastoma - radiotherapy | Radiation-Sensitizing Agents - administration & dosage | Time Factors | Brain Neoplasms - blood | Dacarbazine - analogs & derivatives | Valproic Acid - blood | Adult | Female | Brain Neoplasms - mortality | Chemotherapy, Adjuvant | Brain Neoplasms - radiotherapy | Valproic Acid - adverse effects | Bone Marrow - drug effects | Chemoradiotherapy - methods | Drug Administration Schedule | Glioblastoma - blood | Kaplan-Meier Estimate | Brain Neoplasms - drug therapy | Radiation-Sensitizing Agents - adverse effects | Disease Progression | Antineoplastic Agents, Alkylating - therapeutic use | Radiation Tolerance - drug effects | Disease-Free Survival | Valproic Acid - administration & dosage | Radiation-Sensitizing Agents - metabolism | Aged | Histone Deacetylase Inhibitors - therapeutic use | Antineoplastic Agents, Alkylating - adverse effects | Glioblastoma - drug therapy | Glioblastoma - mortality | Histone Deacetylase Inhibitors - adverse effects | Divalproex | Care and treatment | Analysis | Radiation | Temozolomide | Radiotherapy | Valproic acid | Glioblastoma multiforme | Index Medicus | GLIOMAS | DIAGNOSIS | PATIENTS | DISEASE INCIDENCE | RADIOLOGY AND NUCLEAR MEDICINE | BONE MARROW | RADIATION DOSES | TOXICITY | COMPARATIVE EVALUATIONS | BLOOD
Journal Article