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Clinical Cancer Research, ISSN 1078-0432, 10/2008, Volume 14, Issue 20, pp. 6456 - 6468
Purpose: It was the aim of our study to establish an extensive panel of non-small cell lung cancer (NSCLC) xenograft models useful for the testing of novel... 
xenograft | NSCLC | erlotinib | mutational analysis | anti-EGFR therapy | cetuximab | biomarker | TARGETED THERAPY | KRAS MUTATIONS | GROWTH-FACTOR RECEPTOR | NUDE-MICE | TUMOR XENOGRAFTS | GEFITINIB | ONCOLOGY | GENE-EXPRESSION | TYROSINE KINASE INHIBITOR | EGFR MUTATIONS | ANTITUMOR-ACTIVITY | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Adenocarcinoma - pathology | Oligonucleotide Array Sequence Analysis | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - metabolism | Middle Aged | Drug Resistance, Neoplasm | Immunoblotting | Male | Gene Expression Profiling | Adenocarcinoma - metabolism | Biomarkers, Tumor - metabolism | Cetuximab | Disease Models, Animal | Genes, ras - genetics | Antibodies, Monoclonal - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Etoposide - pharmacology | Mutation - genetics | Adenocarcinoma - drug therapy | Small Cell Lung Carcinoma - pathology | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Carboplatin - pharmacology | Quinazolines - pharmacology | Deoxycytidine - analogs & derivatives | Erlotinib Hydrochloride | Paclitaxel - pharmacology | Prognosis | Carcinoma, Squamous Cell - metabolism | Deoxycytidine - pharmacology | Lung Neoplasms - pathology | Small Cell Lung Carcinoma - drug therapy | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | Vinblastine - analogs & derivatives | Polymerase Chain Reaction | Adult | Female | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Large Cell - metabolism | Radiation-Sensitizing Agents - pharmacology | Tumor Suppressor Protein p53 - metabolism | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Protein Kinase Inhibitors - pharmacology | Vinblastine - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Antineoplastic Agents, Phytogenic - pharmacology | Index Medicus
Journal Article
Embo Molecular Medicine, ISSN 1757-4676, 01/2015, Volume 7, Issue 5, pp. 648 - 669
Journal Article
Neuroscience, ISSN 0306-4522, 2017, Volume 346, pp. 298 - 308
Highlights • GDC-0941 monotherapy induced cytotoxicity and showed pro-apoptotic effects in. • glioblastoma multiforme (GBM) cell lines. • GDC-0941 enhanced the... 
Neurology | TMZ | radiotherapy | glioma | GDC-0941 | chemotherapy | PI3K inhibitor | PICTILISIB GDC-0941 | MGMT | DOWN-REGULATION | PROLIFERATION | NEUROSCIENCES | GLYCOGEN-SYNTHASE KINASE-3-BETA | MALIGNANT GLIOMA | IN-VITRO | POTENT | EXPRESSION | GLIOBLASTOMA CELLS | Apoptosis - drug effects | Dacarbazine - therapeutic use | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Brain Neoplasms - pathology | Antineoplastic Agents, Alkylating - pharmacology | Antineoplastic Agents - therapeutic use | Glioblastoma - radiotherapy | Radiation-Sensitizing Agents - therapeutic use | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Antineoplastic Agents - pharmacology | Brain Neoplasms - radiotherapy | Phosphatidylinositol 3-Kinase - metabolism | Cell Survival - drug effects | Neoplasm Invasiveness | Radiation-Sensitizing Agents - pharmacology | Antineoplastic Combined Chemotherapy Protocols | Brain Neoplasms - drug therapy | Sulfonamides - pharmacology | Antineoplastic Agents, Alkylating - therapeutic use | Glioblastoma - therapy | Indazoles - pharmacology | Cell Movement - drug effects | Signal Transduction - drug effects | Sulfonamides - therapeutic use | Glioblastoma - pathology | Brain Neoplasms - therapy | Cell Line, Tumor | Cell Cycle - drug effects | Glioblastoma - drug therapy | Indazoles - therapeutic use | Antimitotic agents | Tumor proteins | Antineoplastic agents | Chemotherapy | Gliomas | Analysis | Cancer | Index Medicus
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Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 13, pp. 3904 - 3915
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Clinical Cancer Research, ISSN 1078-0432, 09/2011, Volume 17, Issue 17, pp. 5638 - 5648
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Clinical Cancer Research, ISSN 1078-0432, 10/2010, Volume 16, Issue 20, pp. 4946 - 4957
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Cancer Research, ISSN 0008-5472, 05/2006, Volume 66, Issue 10, pp. 5354 - 5362
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