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JOURNAL OF VIROLOGY, ISSN 0022-538X, 01/2012, Volume 86, Issue 1, pp. 114 - 120
Persistent human immunodeficiency virus type 1 (HIV-1) infection of resting CD4(+) T cells, unaffected by antiretroviral therapy (ART), provides a long-lived... 
MOLECULAR CHARACTERIZATION | VIREMIA | REPLICATION | VIROLOGY | ANTIVIRAL THERAPY | RAG2(-/-)GAMMA(-/-)(C) MICE | LYMPHOID-TISSUE | ACTIVE ANTIRETROVIRAL THERAPY | REVERSE-TRANSCRIPTASE | MODEL | VIRAL RESERVOIR
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2011, Volume 7, Issue 9, p. e1002231
Journal Article
JOURNAL OF IMMUNOLOGICAL METHODS, ISSN 0022-1759, 05/2014, Volume 407, pp. 127 - 134
C57BL/6 Rag2(-/-)gamma(-/-)(c)CD47(-/-) triple-knockout mice engrafted with fetal human bone marrow, liver, thymus (TKO-BLT) not only develop high levels of... 
IMMUNODEFICIENT MICE | ENGRAFTMENT | ELT humanized mice | Hematopoiesis | HEMATOPOIETIC STEM-CELLS | BIOCHEMICAL RESEARCH METHODS | IMMUNOLOGY | RAG2 | RECONSTITUTION | C57BL/6 Rag2(-/-)gamma(-/-)(c)CD47(-/-) | RECEPTOR-GAMMA-CHAIN
Journal Article
VIROLOGY, ISSN 0042-6822, 04/2008, Volume 373, Issue 2, pp. 342 - 351
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71344
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20169
Several new immunodeficient mouse models for human cell engraftment have recently been introduced that include the Rag2(-/-)gamma c(-/-), NOD/SCID, NOD/SCID... 
HU MOUSE | RESPONSES | TRANSMISSION | ENGRAFTMENT | THERAPY | MULTIDISCIPLINARY SCIENCES | T-CELL DEPLETION | MOUSE MODEL | DEFICIENT | INHIBITORS | HUMAN IMMUNE-SYSTEM | Immunohistochemistry | HIV-1 - pathogenicity | Antigens, CD34 - metabolism | Leukocyte Common Antigens - metabolism | Homeodomain Proteins - metabolism | Humans | Interleukin Receptor Common gamma Subunit - metabolism | DNA-Binding Proteins - deficiency | CD4-Positive T-Lymphocytes - immunology | DNA-Binding Proteins - metabolism | Immunoglobulins - metabolism | HIV Infections - immunology | Flow Cytometry | Disease Susceptibility - immunology | Hematopoiesis | Female | Antibody Formation - immunology | Mucous Membrane - virology | CD4-Positive T-Lymphocytes - cytology | Hematopoietic Stem Cell Transplantation | Interleukin Receptor Common gamma Subunit - deficiency | Cell Lineage | Lymphoid Tissue - cytology | HIV-1 - immunology | Animals | Vagina - virology | Mice | Peritoneum - virology | Cell culture | Animal models | Sexually transmitted diseases--STD | Severe combined immunodeficiency | Viremia | Liver | Chronic infection | Stem cell transplantation | Lymphocytes T | Transplantation | Infections | Kinases | Hematopoietic stem cells | Allografts | Rodents | Human immunodeficiency virus--HIV | CD34 antigen | Antigens | Immunoglobulins | Immune response | Fetuses | Immunodeficiency | Organs | Vagina | CD4 antigen | Disease transmission | RAG2 protein | Life span | Hepatocytes | RAG1 protein | Stem cells | Hematopoietic system | Mutation | Human behavior | Liver transplantation | STD | Sexually transmitted diseases | HIV | Human immunodeficiency virus
Journal Article
Virology, ISSN 0042-6822, 2009, Volume 397, Issue 1, pp. 100 - 103
Journal Article
PLOS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3
Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by immune-mediated destruction of insulin-secreting beta cells of the pancreas. Near complete... 
IN-VITRO | ENGRAFTMENT | IMMUNE CELLS | INTERFERON-GAMMA | RAG2(-/-)GAMMA(-/-)(C) MICE | MULTIDISCIPLINARY SCIENCES | MODEL | DIFFERENTIATION | HUMAN-IMMUNODEFICIENCY-VIRUS | TRANSPLANTATION | BLOOD
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 06/2005, Volume 1044, Issue 1, pp. 236 - 243
: Although many biologic principles are conserved in mice and humans, species‐specific differences exist, for example, in susceptibility and response to... 
human adaptive immune system | Rag2−/−γc−/− mice | newborn xenotransplantation | CD34+ cells | Human adaptive immune system | cells | Newborn xenotransplantation | Rag2 | CD34 | mice | Immune systems | Human | Surgical implants | Biomedical materials | Adaptive systems | In vivo testing | In vivo tests | Mice
Journal Article
PLOS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6
Background: Humanized mice generate a lymphoid system of human origin subsequent to transplantation of human CD34+ cells and thus are highly susceptible to HIV... 
VIRUS | THERAPY | PHARMACOKINETICS | RAG2(-/-)GAMMA(-/-)(C) MICE | REVERSE-TRANSCRIPTASE | IN-VIVO | BIOLOGY | SCID-HU MOUSE | MODEL | RILPIVIRINE | T-CELLS
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2010, Volume 5, Issue 10
Background: Passive transfer of antibodies not only provides immediate short-term protection against disease, but also can be exploited as a therapeutic tool.... 
RESPONSES | HU MICE | MEMORY B-CELLS | VIRUS-INFECTION | GERMINAL-CENTER FORMATION | RAG2(-/-)GAMMA(-/-)(C) MICE | HEMATOPOIETIC STEM-CELLS | MOUSE MODEL | IN-VIVO | BIOLOGY | DIFFERENTIATION
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 7, p. e1004291
The role of plasmacytoid dendritic cells (pDC) in human immunodeficiency virus type 1 (HIV-1) infection and pathogenesis remains unclear. HIV-1 infection in... 
PERSISTENT LCMV INFECTION | INTERFERON-PRODUCING CELLS | CD4(+) T-CELLS | MICROBIOLOGY | HIV-1-INFECTED PATIENTS | CHRONIC VIRAL-INFECTION | VIROLOGY | RAG2(-/-)GAMMA(-/-)(C) MICE | IMMUNE ACTIVATION | IMMUNODEFICIENCY VIRUS-INFECTION | PATHOGENIC SIV INFECTION | PARASITOLOGY | IFN-ALPHA | Liver - virology | HIV-1 - pathogenicity | Interferons | Virus Replication - genetics | Dendritic Cells - immunology | Humans | Immunoenzyme Techniques | HIV Infections - immunology | Liver - immunology | Flow Cytometry | HIV Infections - pathology | Fetus - virology | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Antibodies, Monoclonal - immunology | HIV Infections - virology | RNA, Messenger - genetics | Cells, Cultured | DNA Replication | Virus Replication - immunology | HIV-1 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Fetus - cytology | Animals | Fetus - immunology | Viremia - immunology | Liver - cytology | Mice | Mice, Inbred BALB C | Immunopathology | Care and treatment | Patient outcomes | Monoclonal antibodies | Development and progression | Research | Biological response modifiers | HIV infection | HIV | Acquired immune deficiency syndrome | Pathogenesis | Lymphocytes | Laboratories | AIDS | Software | Infections | Human immunodeficiency virus | Gene expression | Immune system | Apoptosis
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 11/2013, Volume 208, Issue suppl 2, pp. S155 - S159
Journal Article
Methods, ISSN 1046-2023, 2011, Volume 53, Issue 1, pp. 102 - 109
Current antiretroviral therapies would greatly benefit from the concurrent removal of integrated HIV-1 proviral DNA from the patient’s cells. In this review,... 
Human immunodeficiency virus type 1 | Recombinase | Rag2 −/−γc | In vitro evolution | Long terminal repeat | Humanized MICE | Rag2 |