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Journal Article
Toxicological sciences : an official journal of the Society of Toxicology, ISSN 1096-6080, 10/2012, Volume 129, Issue 2, pp. 332 - 345
Drug-induced liver injury (DILI) in humans is difficult to predict using classical in vitro cytotoxicity screening and regulatory animal studies. This explains... 
Mitochondria, Liver - drug effects | Animals | Humans | Mice | Mice, Inbred BALB C | Membrane Potential, Mitochondrial - drug effects | Chemical and Drug Induced Liver Injury - etiology | Index Medicus | DILI | screening | drugs | mitochondria | hepatotoxicity | prediction | chemicals
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 10/2012, Volume 129, Issue 2, pp. 332 - 345
Journal Article
Archives of Toxicology, ISSN 0340-5761, 8/2017, Volume 91, Issue 8, pp. 2921 - 2938
The FDA has approved 31 small-molecule kinase inhibitors (KIs) for human use as of November 2016, with six having black box warnings for hepatotoxicity (BBW-H)... 
Biomedicine, general | Mitochondrion | Drug induced liver injury | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Submitochondrial particles | Pharmacology/Toxicology | Hepatotoxicity | Kinase inhibitor | INJURY | DASATINIB | SORAFENIB | CELL-DEATH | POLYMORPHISMS | METABOLISM | RESPIRATION | ASSAYS | MICE | TOXICOLOGY | INDUCED HEPATOTOXICITY | Predictive Value of Tests | Mitochondria, Liver - pathology | Reactive Oxygen Species - metabolism | Species Specificity | Cytochromes c - metabolism | Risk Factors | Rats | Male | Membrane Potential, Mitochondrial - drug effects | Rats, Sprague-Dawley | Oxygen - metabolism | Dose-Response Relationship, Drug | Mitochondria, Liver - drug effects | Protein Kinase Inhibitors - administration & dosage | Drug Labeling | Animals | Sensitivity and Specificity | Protein Kinase Inhibitors - toxicity | Female | Chemical and Drug Induced Liver Injury - etiology | Cytochrome c | Liability (Law) | Drug approval | Liver | Cytochrome | Reactive oxygen species | Inhibitor drugs | Toxicity | Pathogenesis | Labelling | Cytotoxicity | Risk factors | Mitochondria | Rodents | Black boxes | Membrane potential | Swelling | Byproducts | Oxygen consumption | Marking | Risk analysis | Sensitivity | Liability | Inhibitors | Electron transport | In vitro methods and tests | Index Medicus | Organ Toxicity and Mechanisms
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 50, pp. 42165 - 42179
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 1/2008, Volume 308, Issue 1, pp. 75 - 83
Journal Article
Journal Article
Cell Biochemistry and Biophysics, ISSN 1085-9195, 9/2014, Volume 70, Issue 1, pp. 367 - 381
Journal Article
Metallomics, ISSN 1756-5901, 1/2013, Volume 5, Issue 2, pp. 152 - 166
Journal Article