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Genes and Development, ISSN 0890-9369, 02/2011, Volume 25, Issue 4, pp. 350 - 362
Repair of dsDNA breaks requires processing to produce 3'-terminated ssDNA. We biochemically reconstituted DNA end resection using purified human proteins:... 
BLM helicase | DNA2 nuclease | DNA break repair | EXO1 nuclease | DNA end resection | Homologous recombination | NUCLEASE ACTIVITY | BLOOMS-SYNDROME HELICASE | HUMAN EXONUCLEASE 1 | ESCHERICHIA-COLI | MISMATCH REPAIR | DEVELOPMENTAL BIOLOGY | DOUBLE-STRAND BREAK | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | homologous recombination | GENETICS & HEREDITY | MRE11 NUCLEASE | MITOTIC RECOMBINATION | RECQ HELICASE | RecQ Helicases - metabolism | Humans | DNA Repair Enzymes - genetics | Replication Protein A - physiology | Multiprotein Complexes - genetics | RecQ Helicases - genetics | DNA Repair - genetics | DNA Breaks, Double-Stranded | DNA Breaks, Single-Stranded | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Multiprotein Complexes - metabolism | Replication Protein A - genetics | DNA Repair Enzymes - metabolism | Cell Cycle Proteins - genetics | Exodeoxyribonucleases - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | RecQ Helicases - physiology | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Replication Protein A - metabolism | DNA-Binding Proteins - genetics | Multiprotein Complexes - physiology | DNA Helicases - metabolism | Models, Biological | Exodeoxyribonucleases - metabolism | Exodeoxyribonucleases - physiology | Nuclear Proteins - physiology | In Vitro Techniques | Cell Cycle Proteins - physiology | DNA Helicases - physiology | Protein Binding - physiology | Index Medicus | Research Paper
Journal Article
Genes and Development, ISSN 0890-9369, 10/2008, Volume 22, Issue 20, pp. 2767 - 2772
A key cellular response to DNA double-strand breaks ( DSBs) is 5 '-to-3 ' DSB resection by nucleases to generate regions of ssDNA that then trigger cell cycle... 
DNA damage checkpoint | Exonuclease 1 | DNA resection | DNA repair | RecQ helicases | ATR | RECOMBINATION | RPA | PROTEIN | DEVELOPMENTAL BIOLOGY | DAMAGE CHECKPOINT ACTIVATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | EXONUCLEASE-1 | REPAIR | REPLICATION FORKS | GENETICS & HEREDITY | END RESECTION | RecQ Helicases - metabolism | Saccharomyces cerevisiae - genetics | Humans | Bloom Syndrome - metabolism | RecQ Helicases - genetics | Bone Neoplasms - pathology | DNA Breaks, Double-Stranded | Bone Neoplasms - metabolism | Saccharomyces cerevisiae - metabolism | Transfection | Recombination, Genetic | Bone Neoplasms - genetics | Tumor Cells, Cultured | DNA Helicases - genetics | Osteosarcoma - metabolism | DNA Repair - drug effects | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | DNA Helicases - metabolism | Plasmids | RecQ Helicases - antagonists & inhibitors | Exodeoxyribonucleases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | DNA Helicases - antagonists & inhibitors | Osteosarcoma - genetics | Microscopy, Fluorescence | Osteosarcoma - pathology | Saccharomyces cerevisiae - growth & development | Nucleases | DNA damage | Analysis | Chemical properties | Research | Helicases | Mutation (Biology) | Index Medicus | Research Communication
Journal Article
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 2015, Volume 208, Issue 5, pp. 545 - 562
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2012, Volume 46, Issue 1, pp. 43 - 53
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 12/2007, Volume 21, Issue 23, pp. 3073 - 3084
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 12/2017, Volume 216, Issue 12, pp. 3991 - 4005
Journal Article
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7417, pp. 581 - 584
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 11/2014, Volume 28, Issue 22, pp. 2477 - 2491
Journal Article