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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, pp. 12015 - 12020
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, p. 12015
Receptor activity-modifying proteins (RAMPs) are widely expressed in human tissues and, in some cases, have been shown to affect surface expression or ligand... 
G protein-coupled receptors | Redundancy | Genomics | Data processing | Phylogeny | Tissues | Coevolution | Receptor activity modifying proteins | Human tissues | Proteins | Ramps | Tissue | Signal transduction | Signaling | Receptors | Phylogenetics | Ligands
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2016, Volume 291, Issue 22, pp. 11657 - 11675
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2015, Volume 58, Issue 6, pp. 1040 - 1052
Association of receptor activity-modifying proteins (RAMP1-3) with the G protein-coupled receptor (GPCR) calcitonin receptor-like receptor (CLR) enables... 
CALCITONIN-RECEPTOR | AMYLIN RECEPTORS | GENE-RELATED PEPTIDE | CRYSTAL-STRUCTURE | MOLECULAR RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXTRACELLULAR DOMAIN | PARATHYROID-HORMONE | N-TERMINUS | CGRP RECEPTOR | ADRENOMEDULLIN | CELL BIOLOGY | Humans | Protein Multimerization | Adrenomedullin - chemistry | Peptides - genetics | Cercopithecus aethiops | Molecular Sequence Data | Crystallography, X-Ray | Receptor Activity-Modifying Protein 1 - chemistry | Receptor Activity-Modifying Protein 2 - chemistry | Calcitonin Gene-Related Peptide - chemistry | Peptides - metabolism | Calcitonin Gene-Related Peptide - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Peptides - chemistry | Protein Structure, Secondary | Calcitonin Receptor-Like Protein - chemistry | Models, Molecular | Receptor Activity-Modifying Protein 1 - metabolism | Calcitonin Gene-Related Peptide - genetics | Receptor Activity-Modifying Protein 2 - metabolism | Adrenomedullin - metabolism | Binding Sites - genetics | Receptor Activity-Modifying Protein 1 - genetics | Calcitonin Receptor-Like Protein - metabolism | Adrenomedullin - genetics | Sequence Homology, Amino Acid | Animals | Calcitonin Receptor-Like Protein - genetics | Protein Binding | Receptor Activity-Modifying Protein 2 - genetics | Mutation | COS Cells | G proteins | Peptides | Structure | Crystals | Membrane proteins | Protein binding | BASIC BIOLOGICAL SCIENCES
Journal Article
Annual review of pharmacology and toxicology, ISSN 0362-1642, 2016, Volume 56, pp. 469 - 487
Once considered as largely independent functional units, G protein-coupled receptors (GPCRs) are now recognized as having a far more diverse molecular... 
heterodimer | RAMP | CRF | Adrenomedullin | GPR30 | calcium-sensing receptor | GPCR | amylin | VIP | CGRP
Journal Article
Biochemistry, ISSN 0006-2960, 02/2018, Volume 57, Issue 8, pp. 1410 - 1422
The calcitonin receptor-like receptor (CLR) is a class B G protein-coupled receptor (GPCR) that forms the basis of three pharmacologically distinct receptors,... 
GENE-RELATED PEPTIDE | GLUCAGON-LIKE PEPTIDE-1 | 3RD EXTRACELLULAR LOOP | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINUS | GLP-1 RECEPTOR | CRYO-EM STRUCTURE | MUTATIONAL ANALYSIS | CGRP RECEPTOR | BINDING | Molecules | Usage | Calcitonin | Analysis | Ligands (Biochemistry) | G proteins | Research | Peptide hormones
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2013, Volume 168, Issue 4, pp. 822 - 834
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 02/2013, Volume 168, Issue 4, pp. 822 - 834
BACKGROUND AND PURPOSE Although it is established that the receptor activity modifying proteins (RAMPs) can interact with a number of GPCRs, little is known... 
RAMP2 | RAMP3 | CRF1 receptor | FACTOR TYPE-1 | Ramp2(+/-) mice | biased agonism | G-protein coupling | ARRIVE GUIDELINES | VPAC receptor | DIFFERENTIALLY MODULATE | SIGNAL-TRANSDUCTION | MESSENGER-RNA | PITUITARY | COUPLED RECEPTORS | PHARMACOLOGY & PHARMACY | receptor activity-modifying proteins (RAMPs) | RAT-BRAIN | RAMP1 | CALCITONIN RECEPTORS | ADIPOSE-TISSUE
Journal Article
Critical Reviews in Biochemistry and Molecular Biology, ISSN 1040-9238, 01/2016, Volume 51, Issue 1, pp. 65 - 71
Journal Article