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The journal of clinical endocrinology and metabolism, ISSN 1945-7197, 06/2016, Volume 101, Issue 6, pp. 2340 - 2347
...: We previously demonstrated that a monoclonal stimulatory TSHR antibody, M22, activates TSHR/IGF-1R cross talk in orbital fibroblasts/preadipocytes obtained from patients with GO (GO fibroblasts [GOFs... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Orbit - metabolism | Receptor, IGF Type 1 - metabolism | Graves Ophthalmopathy - metabolism | Receptors, Thyrotropin - metabolism | Humans | Hyaluronic Acid - metabolism | Cells, Cultured | Cyclic AMP - metabolism | Receptor Cross-Talk - physiology | Graves Ophthalmopathy - etiology | Index Medicus | Abridged Index Medicus | Original
Journal Article
Biochemical journal, ISSN 1470-8728, 12/2011, Volume 441, Issue 2, pp. 523 - 540
Reactive oxygen and nitrogen species change cellular responses through diverse mechanisms that are now being defined. At low levels, they are signalling... 
Mitochondrion | Oxidative stress | Redox signalling | Neurodegeneration | Autophagy | Nitrative stress | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Kinases - metabolism | Transcription, Genetic - drug effects | Cardiovascular Diseases - physiopathology | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Reactive Nitrogen Species - metabolism | Humans | Oxidative Stress - physiology | Hydrogen Peroxide - pharmacology | Oncogene Proteins - metabolism | Nitric Oxide - physiology | Autophagy - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Parkinson Disease - physiopathology | Lysosomes - physiology | Protein Deglycase DJ-1 | Animals | Signal Transduction - physiology | TOR Serine-Threonine Kinases - physiology | Neoplasms - physiopathology | Index Medicus | neurodegeneration | AMPK, 5′-AMP-activated protein kinase | NBR1, neighbour of BRCA1 (breast cancer early-onset 1) | NGF, nerve growth factor | LC3, light chain 3 | NOX, NADPH oxidase | EM, electron microscopy | TOR, target of rapamycin | ULK, unc (unco-ordinated family member)-51-like kinase | mtDNA, mitochondrial DNA | mTOR, mammalian target of rapamycin | IKKβ, IκB kinase β | LRRK2, leucine-rich repeat kinase 2 | NAC, N-acetyl-L-cysteine | Nrf2, nuclear factor-erythroid 2-related factor 2 | PI3P, phosphatidylinositol 3-phosphate | autophagy | ECH, enoyl-CoA hydratase | BNIP3L, BNIP3-like | Drp1, dynamin-related protein 1 | tfLC3, tandem fluorescently tagged LC3 | NF-κB, nuclear factor κB | BAG, Bcl-2-associated athanogene | Keap1, Kelch-like ECH-associated protein 1 | PE, phosphatidylethanolamine | mitochondrion | 3-MA, 3-methyladenine | UCP, uncoupling protein | IκB, inhibitor of nuclear factor κB | FIP200, focal adhesion kinase family-interacting protein of 200 kDa | PI3K, phosphoinositide 3-kinase | HNE, 4-hydroxynonenal | Review | ALS, amyotrophic lateral sclerosis | redox signalling | ATG, AuTophaGy-related | adenovirus E18 19-kDa-interacting protein | Tzb, trastuzumab | mETC, mitochondrial electron-transport chain | Rubicon, RUN domain- and cysteine-rich domain-containing beclin-1-interacting protein | VDAC, voltage-dependent anion channel | IP3, inositol 1,4,5-trisphosphate | RFP, red fluorescent protein | ROS, reactive oxygen species | TNFα, tumour necrosis factor α | PINK1, PTEN (phosphatase and tensin homologue deleted on chromosome 10)-induced kinase 1 | GFP, green fluorescent protein | LAMP, lysosome-associated membrane protein | JNK1, c-Jun N-terminal kinase 1 | TAC, transverse aortic constriction | GABARAP, GABAA (γ-aminobutyric acid type A)-receptor-associated protein | HIF-1, hypoxia-inducible factor 1 | NOS, nitric oxide synthase | siRNA, small interfering RNA | SOD, superoxide dismutase | RLS, reactive lipid species | nitrative stress | RNS, reactive nitrogen species | ER, endoplasmic reticulum | TIGAR, TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator | Vps34, vacuolar protein sorting 34 | oxidative stress | BNIP, Bcl-2
Journal Article