X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7968) 7968
Book Chapter (98) 98
Book / eBook (7) 7
Publication (2) 2
Conference Proceeding (1) 1
Dissertation (1) 1
Newsletter (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (6528) 6528
life sciences & biomedicine (5999) 5999
animals (4924) 4924
humans (4779) 4779
mice (2588) 2588
signal transduction (1783) 1783
phosphorylation (1694) 1694
biochemistry & molecular biology (1537) 1537
cell biology (1450) 1450
male (1430) 1430
female (1413) 1413
rats (1238) 1238
cells, cultured (1225) 1225
immunology (1190) 1190
oncology (1158) 1158
protein-tyrosine kinases - metabolism (1157) 1157
receptor protein-tyrosine kinases - biosynthesis (1126) 1126
cell line (1106) 1106
receptor protein-tyrosine kinases - genetics (937) 937
molecular sequence data (927) 927
gene expression (885) 885
abridged index medicus (860) 860
proteins (855) 855
transfection (817) 817
receptor protein-tyrosine kinases - metabolism (748) 748
tumor cells, cultured (719) 719
research article (696) 696
rna, messenger - biosynthesis (683) 683
kinases (675) 675
amino acid sequence (672) 672
research (669) 669
neurosciences (652) 652
neurosciences & neurology (649) 649
tyrosine (610) 610
base sequence (590) 590
cell line, tumor (580) 580
immunohistochemistry (565) 565
proto-oncogene proteins - biosynthesis (557) 557
mice, inbred c57bl (553) 553
signal transduction - drug effects (546) 546
science & technology - other topics (528) 528
multidisciplinary sciences (526) 526
receptors (503) 503
adult (481) 481
signal transduction - physiology (481) 481
proto-oncogene proteins - genetics (472) 472
apoptosis (464) 464
physiological aspects (463) 463
mutation (455) 455
blotting, western (444) 444
middle aged (439) 439
kinetics (436) 436
mice, knockout (427) 427
tyrosine - metabolism (427) 427
enzyme inhibitors - pharmacology (419) 419
polymerase chain reaction (419) 419
analysis (414) 414
ligands (410) 410
rna, messenger - metabolism (408) 408
protein-tyrosine kinases - genetics (406) 406
enzyme activation (402) 402
protein-tyrosine kinases - antagonists & inhibitors (397) 397
proto-oncogene proteins - metabolism (395) 395
cancer (393) 393
hematology (389) 389
gene expression regulation (385) 385
cell division - drug effects (384) 384
protein-tyrosine kinases - biosynthesis (367) 367
rna, messenger - genetics (360) 360
genetic aspects (357) 357
signal transduction - immunology (356) 356
reverse transcriptase polymerase chain reaction (351) 351
dna - biosynthesis (347) 347
rats, sprague-dawley (343) 343
medicine, research & experimental (333) 333
research & experimental medicine (333) 333
aged (328) 328
cell proliferation (326) 326
mice, transgenic (323) 323
rodents (322) 322
protein-tyrosine kinase (319) 319
time factors (317) 317
cell differentiation (315) 315
endocrinology & metabolism (312) 312
gene expression regulation, neoplastic (312) 312
genetics & heredity (312) 312
medicine (311) 311
t-lymphocytes - immunology (303) 303
biology (294) 294
genes (292) 292
intracellular signaling peptides and proteins (289) 289
mice, inbred balb c (286) 286
physiology (286) 286
protein binding (285) 285
cytokines - biosynthesis (284) 284
receptors, vascular endothelial growth factor (279) 279
transcription, genetic (279) 279
dose-response relationship, drug (278) 278
pharmacology & pharmacy (276) 276
cell division (272) 272
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8052) 8052
Chinese (30) 30
Japanese (30) 30
French (6) 6
Russian (5) 5
German (3) 3
Spanish (2) 2
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PloS one, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e34412 - e34412
Background: Protein-tyrosine phosphatase 1B (PTP1B) is a physiological regulator of glucose homeostasis and body mass, and has been implicated in endoplasmic reticulum (ER) stress... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Line | Adipocytes, Brown - metabolism | Unfolded Protein Response - genetics | eIF-2 Kinase - metabolism | Humans | Male | Signal Transduction - genetics | eIF-2 Kinase - chemistry | Endoplasmic Reticulum Stress - genetics | Gene Knockout Techniques | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - deficiency | Cell Differentiation - genetics | Phosphorylation - genetics | Tyrosine - metabolism | Animals | Adipocytes, Brown - enzymology | Activating Transcription Factor 4 - biosynthesis | Eukaryotic Initiation Factor-2 - metabolism | Mice | Protein Biosynthesis - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Enzyme Activation - genetics | Adipocytes, Brown - cytology | Regulators | Phosphorylation | Adipose tissue | Homeostasis | mRNA | Adipocytes | Glucose | Kinases | Phosphatase | Metabolic response | Proteins | Protein folding | Rodents | Protein-tyrosine phosphatase 1B | Adipose tissue (brown) | Tyrosine | Stresses | Obesity | Medical research | Protein biosynthesis | Protein deficiency | Metabolism | Stress | Substrates | Studies | Nutrition research | Signaling | Thermogenesis | Body mass | Protein synthesis | Insulin resistance | Diabetes | Endoplasmic reticulum | Protein-tyrosine-phosphatase | Apoptosis | Index Medicus
Journal Article
Nature (London), ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 453 - 457
Journal Article
Nature (London), ISSN 1476-4687, 03/2014, Volume 508, Issue 7494, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably... 
Antineoplastic Agents/administration & dosage | Transforming Growth Factor beta/metabolism | Humans | Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors | Indoles/administration & dosage | Flow Cytometry | Receptor, Platelet-Derived Growth Factor beta/biosynthesis | Proto-Oncogene Proteins B-raf/antagonists & inhibitors | ErbB Receptors/biosynthesis | Melanoma/drug therapy | Female | Cell Proliferation/drug effects | Sulfonamides/administration & dosage | Gene Library | Cellular Senescence/drug effects | Receptor Protein-Tyrosine Kinases/biosynthesis | Drug Resistance, Neoplasm/drug effects | Gene Expression Regulation, Neoplastic/drug effects | SOXE Transcription Factors/deficiency | Signal Transduction/drug effects | Protein Kinase Inhibitors/administration & dosage | Vemurafenib | Animals | Mice | RNA, Small Interfering | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Melanoma - genetics | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 07/2014, Volume 130, Issue 1, pp. 145 - 159
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2014, Volume 111, Issue 52, pp. 18661 - 18666
...) represent a common molecular subset of non-small cell lung cancer (NSCLC) cases. EGFR mutations predict sensitivity to EGFR tyrosine kinase inhibitors (TKIs... 
Genes | Epidermal cells | Cell lines | Open reading frames | Growth factor receptors | Viability | Genetic mutation | Genetic screening | Cells | Lung neoplasms | ORF | Epidermal growth factor receptor | Non-small cell lung cancer | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Receptor, trkB | Humans | Membrane Glycoproteins - biosynthesis | Receptor Protein-Tyrosine Kinases - biosynthesis | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Receptor, Fibroblast Growth Factor, Type 1 - genetics | MAP Kinase Signaling System | Proto-Oncogene Proteins c-mos - genetics | Receptor, trkA - biosynthesis | Protein-Tyrosine Kinases - genetics | Protein-Tyrosine Kinases - biosynthesis | Proto-Oncogene Proteins c-raf - biosynthesis | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - biosynthesis | Lung Neoplasms - enzymology | Proto-Oncogene Proteins c-raf - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Glycoproteins - genetics | Receptor, Fibroblast Growth Factor, Type 2 - biosynthesis | Gene Expression Regulation, Enzymologic | Receptor Protein-Tyrosine Kinases - genetics | Cell Line, Tumor | Receptor, trkA - genetics | Carcinoma, Non-Small-Cell Lung - enzymology | Proto-Oncogene Proteins c-mos - biosynthesis | Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Protein research | Oncology, Experimental | Genetic aspects | Research | Lung cancer, Non-small cell | Gene expression | Cancer | Epidermal growth factor | Mutation | Lung cancer | Index Medicus | non-small cell lung cancer | Biological Sciences | epidermal growth factor receptor
Journal Article
PloS one, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e115140 - e115140
Tyro3, Axl and Mertk (TAM) receptor tyrosine kinases play multiple functional roles by either providing intrinsic trophic support for cell growth or regulating the expression of target genes that are important... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Receptor Protein-Tyrosine Kinases - biosynthesis | Apoptosis - genetics | Recombinant Proteins | Proto-Oncogene Proteins - biosynthesis | Neurogenesis - genetics | Receptor, trkA - biosynthesis | c-Mer Tyrosine Kinase | Brain-Derived Neurotrophic Factor - biosynthesis | Proto-Oncogene Proteins - metabolism | Receptors, Nerve Growth Factor - biosynthesis | Cell Survival | Receptor, trkB - biosynthesis | Cells, Cultured | Proto-Oncogene Proteins - genetics | Hippocampus - cytology | Nerve Growth Factors - biosynthesis | Receptor Protein-Tyrosine Kinases - metabolism | Mice, Knockout | Hippocampus - metabolism | Animals | Receptor Protein-Tyrosine Kinases - genetics | Receptor, trkC - biosynthesis | Mice | Neural Stem Cells - metabolism | Brain | Nerve growth factor | Tubulins | Cell differentiation | Neurons | Stem cells | Cell proliferation | Neurosciences | Neurobiology | Central nervous system | Nervous system | Kinases | Neurogenesis | Neuronal-glial interactions | Axl protein | Proteins | Signal transduction | Receptors | Cell activation | Cell growth | Tubulin | Rodents | TrkA protein | Protein-tyrosine kinase receptors | TrkA receptors | Neurotrophins | Growth factors | Tyrosine | Cell survival | Immune response | Axonogenesis | Inflammation | Gene expression | Survival | Medicine | Brain-derived neurotrophic factor | Neural stem cells | TrkB receptors | Differentiation | Hippocampus | Apoptosis | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 03/2013, Volume 288, Issue 10, pp. 7410 - 7419
Journal Article