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Redox biology, ISSN 2213-2317, 2014, Volume 2, Issue 1, pp. 411 - 429
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2008, Volume 57, Issue 9, pp. 2461 - 2469
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 6, p. e66611
Accumulation of advanced glycation end products (AGEs) in joints is important in the development of cartilage destruction and damage in age-related osteoarthritis (OA... 
HUMAN ARTICULAR-CARTILAGE | COLLAGEN | STIMULATION | SYNOVIAL FIBROBLASTS | MATRIX-METALLOPROTEINASE-13 | MULTIDISCIPLINARY SCIENCES | HUMAN OSTEOARTHRITIC CHONDROCYTES | PPAR-GAMMA | KAPPA-B | MAILLARD REACTION-PRODUCTS | EXPRESSION | Enzyme-Linked Immunosorbent Assay | Humans | Gene Expression Regulation - physiology | Osteoarthritis - metabolism | PPAR gamma - metabolism | Toll-Like Receptor 4 - metabolism | Blotting, Western | Matrix Metalloproteinase 13 - metabolism | Collagen - metabolism | Analysis of Variance | Glycation End Products, Advanced - metabolism | HMGB1 Protein - metabolism | Cyclooxygenase 2 - metabolism | Interleukin-6 - metabolism | Receptor for Advanced Glycation End Products | Chondrocytes - metabolism | Receptors, Immunologic - metabolism | Regulations | Transcription factors | Pathogenesis | Collagen (type II) | Interleukin | Antibodies | Arthritis | Kinases | Accumulation | Western blotting | Interleukin 6 | Proteins | Cartilage | Toxicology | Biomedical materials | Down-regulation | Toll-like receptors | Aging | Biocompatibility | Metalloproteinase | Kits | Age | Enzyme-linked immunosorbent assay | Immune system | NF-κB protein | Advanced glycosylation end products | Cytokines | Pioglitazone | c-Jun protein | Inflammation | Glycosylation | TLR4 protein | Gene expression | Joint diseases | Medicine | Signaling | Collagen | Chondrocytes | Diabetes | Cyclooxygenase-2 | Osteoarthritis | Cartilage diseases
Journal Article
Circulation, ISSN 0009-7322, 08/2006, Volume 114, Issue 6, pp. 597 - 605
Advanced glycation end products ( AGEs) are proteins or lipids that become glycated after exposure to sugars... 
Advanced glycosylation end products | Diabetes mellitus | Vasculature | OXIDE SYNTHASE EXPRESSION | vasculature | CARDIAC & CARDIOVASCULAR SYSTEMS | ADVANCED GLYCOSYLATION ENDPRODUCTS | LOW-DENSITY-LIPOPROTEIN | advanced glycosylation end products | diabetes mellitus | FACTOR-KAPPA-B | IN-VITRO | CELL-SURFACE RECEPTOR | ENDOTHELIAL-CELLS | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | CROSS-LINK BREAKER | EXTRACELLULAR-MATRIX | Basement Membrane - ultrastructure | Reactive Oxygen Species - metabolism | Receptors, Immunologic - physiology | Humans | Diabetic Angiopathies - etiology | Glycation End Products, Advanced - antagonists & inhibitors | Nitric Oxide - analysis | Endothelium, Vascular - chemistry | Basement Membrane - chemistry | Diabetic Angiopathies - physiopathology | Diabetic Angiopathies - pathology | Coronary Artery Disease - physiopathology | Extracellular Matrix - physiology | Up-Regulation - physiology | Coronary Artery Disease - pathology | Monocytes - pathology | Monocytes - physiology | Receptor for Advanced Glycation End Products | NF-kappa B - analysis | Macrophages - physiology | Glycation End Products, Advanced - physiology | Coronary Artery Disease - etiology | Glycation End Products, Advanced - analysis | Macrophages - pathology | Endothelium, Vascular - physiopathology | Nitric Oxide - physiology | Receptors, Immunologic - analysis | Basement Membrane - physiopathology | Extracellular Matrix - ultrastructure | Animals | NF-kappa B - genetics | NF-kappa B - physiology | Endothelium, Vascular - pathology | Signal Transduction - physiology | Protein Binding - physiology
Journal Article
Circulation, ISSN 0009-7322, 02/2002, Volume 105, Issue 7, pp. 816 - 822
Background-The products of nonenzymatic glycation and oxidation of proteins, the advanced glycation end products (AGES... 
Receptors | Inflammation | Cell adhesion molecules | Endothelium | Vasculature | endothelium | vasculature | cell adhesion molecules | CALCIUM-BINDING PROTEINS | CARDIAC & CARDIOVASCULAR SYSTEMS | receptors | GLYCOSYLATION | VASCULAR-DISEASE | N-EPSILON-(CARBOXYMETHYL)LYSINE | S100 FAMILY | MYELOPEROXIDASE | HUMAN ATHEROSCLEROTIC LESIONS | CELL-SURFACE RECEPTOR | inflammation | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | ACCUMULATION | HEMATOLOGY | Endothelium, Vascular - cytology | Immunohistochemistry | Neutrophils - cytology | Blood Vessels - metabolism | Blood Vessels - pathology | Humans | Synovial Membrane - pathology | Endothelium, Vascular - drug effects | RNA, Messenger - metabolism | Receptors, Immunologic - antagonists & inhibitors | Arthritis, Rheumatoid - metabolism | Inflammation - metabolism | E-Selectin - genetics | U937 Cells | Immunoglobulin G - pharmacology | Vascular Cell Adhesion Molecule-1 - genetics | Neutrophils - metabolism | Receptor for Advanced Glycation End Products | Saphenous Vein - cytology | Neutrophils - drug effects | Cells, Cultured | E-Selectin - metabolism | Cell Adhesion - drug effects | Synovial Membrane - metabolism | Arthritis, Rheumatoid - pathology | Intercellular Adhesion Molecule-1 - metabolism | Endothelium, Vascular - metabolism | Glycation End Products, Advanced - pharmacology | Intercellular Adhesion Molecule-1 - genetics | Glycation End Products, Advanced - biosynthesis | Signal Transduction - physiology | Vascular Cell Adhesion Molecule-1 - metabolism | Receptors, Immunologic - metabolism
Journal Article
Rheumatology, ISSN 1462-0324, 05/2011, Volume 50, Issue 5, pp. 838 - 851
Methods. OA chondrocytes were stimulated with AGE-modified BSA (AGE-BSA). Gene expression of IL-6 and IL-8 was quantified by TaqMan assays and the production... 
Advanced glycation end products | Receptor for advanced glycation end product | Nuclear factor-κB | Interleukin-8 | Osteoarthritis | Interleukin-6 | Mitogen-activated protein kinases | INHIBITS INTERLEUKIN-1-BETA-INDUCED EXPRESSION | RHEUMATOID-ARTHRITIS | COLLAGEN | SYNOVIAL-FLUID | nuclear factor-kappa B | RHEUMATOLOGY | CROSS-LINKS | HUMAN ARTICULAR-CARTILAGE | DIABETES-MELLITUS | mitogen-activated protein kinases | IN-VIVO | NITRIC-OXIDE | MAILLARD REACTION-PRODUCTS | S100 Calcium-Binding Protein A4 | Humans | Middle Aged | Male | NF-kappa B - metabolism | Receptors, Immunologic - antagonists & inhibitors | Dose-Response Relationship, Drug | Chondrocytes - drug effects | MAP Kinase Kinase 4 - metabolism | Adult | Female | Interleukin-8 - metabolism | Osteoarthritis - pathology | S100 Proteins - pharmacology | Interleukin-6 - metabolism | Receptor for Advanced Glycation End Products | Chondrocytes - metabolism | Chondrocytes - pathology | NF-kappa B - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Cells, Cultured | Osteoarthritis - metabolism | Antibodies - pharmacology | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Glycation End Products, Advanced - pharmacology | Signal Transduction - physiology | Aged | Receptors, Immunologic - metabolism | Mitogen-Activated Protein Kinases - metabolism | nuclear factor-κB | Basic Science
Journal Article
Journal Article
Diabetes care, ISSN 1935-5548, 2011, Volume 34, Issue 7, pp. 1610 - 1616
...). Several anti-inflammatory and cell-protective mechanisms, including advanced glycation end product (AGE) receptor-1 (AGER1) and sirtuin... 
METABOLIC SYNDROME | OXIDATIVE STRESS | OXIDANT STRESS | RISK-FACTOR | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | FOODS | GLYCOTOXINS | MEDIATORS | EXPRESSION |