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The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 15, pp. 1419 - 1428
Journal Article
Neuropharmacology, ISSN 0028-3908, 08/2013, Volume 71, pp. 56 - 69
Using bioluminescence resonance energy transfer and proximity ligation assays, we obtained the first direct evidence that adenosine A1 receptors (A1Rs) form... 
G protein-coupled receptor | Allosteric interaction | Proximity ligation assay | Binding parameters | cooperativity | Two-state dimer receptor model | Binding parameters cooperativity | Adenosine Deaminase - chemistry | Central Nervous System Stimulants - pharmacology | Adenosine Deaminase - metabolism | Humans | Adenosine A1 Receptor Antagonists - pharmacology | Neurons - cytology | Cerebral Cortex - cytology | Recombinant Fusion Proteins - metabolism | Adenosine A1 Receptor Antagonists - metabolism | Cerebral Cortex - metabolism | Nerve Tissue Proteins - chemistry | Adenosine A1 Receptor Agonists - pharmacology | Cattle | HEK293 Cells | Caffeine - pharmacology | Central Nervous System Stimulants - metabolism | Cell Membrane - metabolism | Neurons - metabolism | Cerebral Cortex - drug effects | Neurons - drug effects | Dimerization | Receptor, Adenosine A1 - genetics | Cell Membrane - drug effects | Caffeine - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Allosteric Site - drug effects | Nerve Tissue Proteins - agonists | Bacterial Proteins - genetics | Receptor, Adenosine A1 - chemistry | Adenosine A1 Receptor Agonists - chemistry | Receptor, Adenosine A1 - metabolism | Nerve Tissue Proteins - metabolism | Animals | Models, Biological | Caffeine - chemistry | Central Nervous System Stimulants - chemistry | Adenosine A1 Receptor Agonists - metabolism | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Kinetics | Adenosine A1 Receptor Antagonists - chemistry | Luminescent Proteins - metabolism
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 01/2013, Volume 65, Issue 1, pp. 30 - 34
Objectives  With the aim of finding the structural features governing binding activity and selectivity against adenosine receptors (ARs), several 3‐subtituted... 
binding affinity | adenosine receptor ligands | amide derivatives | carbamate derivatives | coumarins | SERIES | 3-PHENYLCOUMARINS | DISCOVERY | MEDICINAL CHEMISTRY | POTENT | LIGANDS | PHARMACOLOGY | PHARMACOLOGY & PHARMACY | MAO | INHIBITORS | ANTAGONISTS | Coumarins - metabolism | Cricetulus | Amides - chemical synthesis | Humans | Adenosine A1 Receptor Antagonists - pharmacology | Structure-Activity Relationship | Adenosine A1 Receptor Antagonists - metabolism | Carbamates - chemistry | Carbamates - metabolism | Receptors, Purinergic P1 - chemistry | Adenosine A2 Receptor Antagonists - metabolism | Receptor, Adenosine A3 - metabolism | Amides - metabolism | Receptor, Adenosine A2A - genetics | Adenosine A3 Receptor Antagonists - pharmacology | Receptor, Adenosine A1 - genetics | CHO Cells | Carbamates - pharmacology | Amides - pharmacology | Binding, Competitive | Recombinant Proteins - metabolism | Cricetinae | Recombinant Proteins - antagonists & inhibitors | Hydroxylation | Receptors, Purinergic P1 - genetics | Receptor, Adenosine A1 - chemistry | Receptor, Adenosine A2A - metabolism | Receptor, Adenosine A1 - metabolism | Coumarins - pharmacology | Adenosine A2 Receptor Antagonists - pharmacology | Carbamates - chemical synthesis | Receptor, Adenosine A3 - chemistry | Animals | Coumarins - chemical synthesis | Amides - chemistry | Receptor, Adenosine A2A - chemistry | Receptor, Adenosine A3 - genetics | Adenosine A3 Receptor Antagonists - metabolism | Kinetics | Receptors, Purinergic P1 - metabolism | Adenosine A1 Receptor Antagonists - chemistry | Adenosine A2 Receptor Antagonists - chemistry | Adenosine A3 Receptor Antagonists - chemistry | Carbamates | Coumarins | Hydroxides | Chemical properties | Derivatives (Financial instruments) | Adenosine
Journal Article
Journal Article
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 05/2017, Volume 60, Issue 10, pp. 4327 - 4341
Journal Article