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Molecular neurobiology, ISSN 0893-7648, 8/2015, Volume 52, Issue 1, pp. 664 - 678
.... Here, we show that activation of A2A adenosine receptor (AR) with an FDA-approved agonist potently permeabilizes an in vitro primary human BBB (hBBB... 
A2A adenosine receptor | Neurology | Neurosciences | Biomedicine | Tight and adherens junctions | Blood-brain barrier | Neurobiology | Paracellular permeability | Cell Biology | Rho-GTPase | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Stress Fibers - drug effects | Humans | Deoxycytidine - pharmacology | rhoA GTP-Binding Protein - metabolism | Antineoplastic Agents - therapeutic use | Receptors, Adenosine A2 - metabolism | Adherens Junctions - metabolism | Adenosine A2 Receptor Agonists - pharmacology | T-Lymphocytes - drug effects | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Phosphorylation - drug effects | Tight Junctions - drug effects | Tight Junctions - metabolism | Cell Line | Endothelial Cells - metabolism | Jurkat Cells | Mice, Inbred C57BL | Electric Impedance | Down-Regulation - drug effects | Blood-Brain Barrier - metabolism | Cell Movement - drug effects | Focal Adhesions - drug effects | Stress Fibers - metabolism | Animals | Signal Transduction - drug effects | T-Lymphocytes - cytology | Endothelial Cells - cytology | Cell Membrane Permeability - drug effects | Focal Adhesions - metabolism | Glioblastoma - pathology | Adherens Junctions - drug effects | Glioblastoma - drug therapy | Endothelial Cells - enzymology | Deoxycytidine - analogs & derivatives | Endothelial Cells - drug effects | Index Medicus
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