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Journal of Neuroscience, ISSN 0270-6474, 2013, Volume 33, Issue 28, pp. 11390 - 11399
Adenosine is a neuromodulator acting through inhibitory A1 receptors (A1Rs) and facilitatory A2ARs, which have similar affinities for adenosine. It has been... 
Mice, Inbred C57BL | Male | Receptor, Adenosine A2A - physiology | Pyrimidines - pharmacology | Mice, Knockout | Triazoles - pharmacology | Adenosine A2 Receptor Antagonists - pharmacology | Animals | 5'-Nucleotidase - physiology | Adenosine - metabolism | Corpus Striatum - drug effects | Corpus Striatum - physiology | Female | Mice
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 02/2015, Volume 87, Issue 2, pp. 305 - 313
Recently we identified a sodium ion binding pocket in a high-resolution structure of the human adenosine A2A receptor. In the present study we explored this... 
Dose-Response Relationship, Drug | Mutation - physiology | Allosteric Regulation - physiology | Protein Structure, Secondary | Humans | Binding Sites - physiology | HEK293 Cells | Receptor, Adenosine A2A - chemistry | Crystallography, X-Ray | Receptor, Adenosine A2A - physiology | Sodium - metabolism | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2005, Volume 8, Issue 7, pp. 858 - 859
Caffeine, a component of tea, coffee and cola, induces wakefulness. It binds to adenosine A1 and A2A receptors as an antagonist, but the receptor subtype... 
Arousal - physiology | Wakefulness - drug effects | Animals | Central Nervous System Stimulants - pharmacology | Caffeine - pharmacology | Wakefulness - physiology | Receptor, Adenosine A2A - physiology | Mice | Arousal - drug effects | Mice, Knockout | Psychological aspects | Adenosine | Neural transmission | Regulation | Research | Health aspects | Caffeine
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2011, Volume 117, Issue 1, pp. 100 - 111
Journal Article
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2014, Volume 41, Issue 1, pp. 218 - 231
Abstract Anxiety is one of the most commonly reported psychiatric conditions, but its pathogenesis is poorly understood. Ailments associated with activation of... 
Psychiatry | Allergy and Immunology | Interleukin-1 | Anxiety | Adenosine receptor | Caspase-1 | OXIDATIVE STRESS | ACTIVATION | A(2A) RECEPTORS | POTASSIUM CHANNELS | PSYCHIATRY | CAFFEINE | IMMUNOLOGY | NEUROSCIENCES | ELEVATED PLUS | IMMUNE-SYSTEM | PSYCHIATRIC-DISORDERS | MICE | EXTRACELLULAR ADENOSINE | Potassium - metabolism | KATP Channels - physiology | Receptors, Interleukin-1 Type I - physiology | Nerve Tissue Proteins - deficiency | Receptor, Adenosine A2A - physiology | Interleukin-1beta - genetics | Brain - metabolism | Glyburide - pharmacology | Exploratory Behavior - drug effects | Ion Transport - drug effects | Interleukin-1beta - biosynthesis | Caspase 1 - physiology | Locomotion - drug effects | Receptors, Interleukin-1 Type I - deficiency | Interleukin-1beta - physiology | Nerve Tissue Proteins - physiology | Mice, Inbred C57BL | Amygdala - metabolism | Anxiety - physiopathology | Adenosine - pharmacology | Enzyme Activation - drug effects | Maze Learning - drug effects | Feeding Behavior - drug effects | Mice, Knockout | Receptor, Adenosine A2A - drug effects | Cyclic AMP-Dependent Protein Kinases - physiology | Pyrroles - pharmacology | Animals | Caspase 1 - deficiency | Adenosine - toxicity | Anxiety - chemically induced | Mice | Mice, Inbred BALB C | Carbazoles - pharmacology | Receptor, Adenosine A2A - deficiency | none that are not included in title or abstract
Journal Article