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Science, ISSN 0036-8075, 06/2016, Volume 352, Issue 6292, pp. aad1210 - aad1210
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2012, Volume 189, Issue 9, pp. 4674 - 4683
The complement system contributes to various immune and inflammatory diseases, including cancer. In this study, we investigated the capacity of lung cancer... 
IMMUNE-RESPONSE | IN-VITRO | BRONCHIAL EPITHELIAL-CELLS | COMPLEMENT INHIBITORY PROTEINS | FACTOR-H | SUPPRESSOR-CELLS | IMMUNOLOGY | VEIN ENDOTHELIAL-CELLS | TUMOR-GROWTH | EXPRESSION | T-CELLS | Human Umbilical Vein Endothelial Cells | Carcinoma, Squamous Cell - blood | Adenocarcinoma - pathology | Carcinoma, Squamous Cell - pathology | Humans | Carcinoma, Lewis Lung - immunology | Lung Neoplasms - pathology | Complement C5a - physiology | Complement C5a - biosynthesis | Complement Activation - immunology | Neovascularization, Pathologic - pathology | Tumor Microenvironment - genetics | Respiratory Mucosa - immunology | Female | Neovascularization, Pathologic - immunology | Neovascularization, Pathologic - therapy | Disease Models, Animal | Carcinoma, Non-Small-Cell Lung - pathology | Respiratory Mucosa - cytology | Adenocarcinoma - blood | Adenocarcinoma - immunology | Mice, Inbred C57BL | Carcinoma, Squamous Cell - immunology | Disease Progression | Carcinoma, Lewis Lung - prevention & control | Carcinoma, Non-Small-Cell Lung - immunology | Tumor Microenvironment - immunology | Complement Activation - genetics | Lung Neoplasms - immunology | Receptor, Anaphylatoxin C5a - physiology | Animals | Lung Neoplasms - prevention & control | Carcinoma, Lewis Lung - pathology | Cell Line, Tumor | Immune Tolerance - genetics | Carcinoma, Non-Small-Cell Lung - blood | Complement C5a - genetics | Mice | Receptor, Anaphylatoxin C5a - antagonists & inhibitors | Respiratory Mucosa - metabolism | Cell Line, Transformed
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 06/2018, Volume 25, Issue 6, pp. 472 - 481
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 02/2014, Volume 25, Issue 2, pp. 225 - 231
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7686, pp. 111 - 114
The complement system is a crucial component of the host response to infection and tissue damage. Activation of the complement cascade generates anaphylatoxins... 
ACID | SMALL-MOLECULE | OPIOID RECEPTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | GPCR | OLIGOMERIZATION | IDENTIFICATION | Receptor, Anaphylatoxin C5a - chemistry | Receptor, Anaphylatoxin C5a - genetics | Protein Structure, Secondary | Receptors, G-Protein-Coupled - metabolism | Humans | Imidazoles - chemistry | Benzodioxoles - metabolism | Models, Molecular | Crystallography, X-Ray | Imidazoles - pharmacology | Receptors, Adrenergic, beta-2 - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Animals | Drug Inverse Agonism | HEK293 Cells | Benzodioxoles - chemistry | Mutation | Protein Stability | Receptor, Anaphylatoxin C5a - antagonists & inhibitors | Binding Sites | Benzodioxoles - pharmacology | Receptors, G-Protein-Coupled - chemistry | Imidazoles - metabolism | Receptor, Anaphylatoxin C5a - metabolism | Drugs | Inflammatory bowel diseases | G protein-coupled receptors | Peptides | Complement component C5a | Manufacturing engineering | Complement | Antagonists | Helices | Arthritis | Production costs | Receptors | Reperfusion | Ischemia | Anaphylatoxins | Alzheimer's disease | Neurodegenerative diseases | Psoriasis | Medical treatment | Crystallization | Inflammation | Crohn's disease | Bioavailability | Mode of action | Complement activation | Immunogenicity | Rheumatoid arthritis | Sepsis | Ligands
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 09/2017, Volume 28, Issue 9, pp. 2756 - 2767
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2006, Volume 116, Issue 3, pp. 783 - 796
Journal Article