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Hypertension, ISSN 0194-911X, 02/2012, Volume 59, Issue 2 Suppl 1, pp. 485 - 492
Journal Article
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 02/2012, Volume 59, Issue 2, pp. 300 - 307
Journal Article
Trends in Cardiovascular Medicine, ISSN 1050-1738, 2015, Volume 26, Issue 3, pp. 221 - 228
Abstract Angiotensin II, an important component of renin angiotensin system, is a potent vasopressor and its actions are mostly mediated via angiotensin II... 
Cardiovascular | Heart failure | Hypertension | Renin angiotensin system | Angiotensin receptor blocker | Diabetes mellitus | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTAGONIST | CLINICAL-TRIAL | HEART-FAILURE | DIABETIC-NEPHROPATHY | HYPERTENSIVE PATIENTS | AZILSARTAN MEDOXOMIL | FIMASARTAN | OLMESARTAN | IRBESARTAN | VALSARTAN | Kidney Diseases - physiopathology | Angiotensin II Type 1 Receptor Blockers - adverse effects | Heart Diseases - metabolism | Kidney - pathology | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Receptor, Angiotensin, Type 2 - drug effects | Kidney - metabolism | Drug Interactions | Myocardium - metabolism | Receptor, Angiotensin, Type 1 - drug effects | Drug Therapy, Combination | Kidney Diseases - metabolism | Heart - physiopathology | Kidney - drug effects | Angiotensin II - metabolism | Heart Diseases - physiopathology | Kidney Diseases - drug therapy | Treatment Outcome | Angiotensin II Type 2 Receptor Blockers - adverse effects | Angiotensin II Type 2 Receptor Blockers - therapeutic use | Animals | Receptor, Angiotensin, Type 2 - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Heart - drug effects | Renin-Angiotensin System - drug effects | Heart Diseases - drug therapy | Heart | Pharmacy | Angiotensin converting enzyme | Atherosclerosis | Angiotensin | Physiological aspects | Patient compliance | Studies | Cardiac arrhythmia | Advantages | Cardiomyopathy | Mortality | Inflammation | Diabetes | Kidney diseases | Metabolism
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 2015, Volume 308, Issue 9, pp. H1007 - H1019
In diabetic patients, left ventricular (LV) remodeling is highly prevalent; however, little is known about the impact of diabetes on right ventricular (RV)... 
Heart failure | Diabetic cardiomyopathy | Angiotensin-(1–7) | Right ventriclular fibrosis | heart failure | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | PULMONARY-HYPERTENSION | right ventriclular fibrosis | HEART-FAILURE | diabetic cardiomyopathy | AVE-0991 | RAT MODEL | HYPERTROPHY | PATHWAY | angiotensin-(1-7) | PERIPHERAL VASCULAR DISEASE | RECEPTOR MAS | DYSFUNCTION | ECHOCARDIOGRAPHY | CONVERTING-ENZYME | Diabetic Cardiomyopathies - drug therapy | Diabetic Cardiomyopathies - etiology | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | Coculture Techniques | Transforming Growth Factor beta1 - metabolism | Ventricular Dysfunction, Right - blood | Receptor, Angiotensin, Type 2 - drug effects | Male | Peptide Fragments - pharmacology | Diabetes Mellitus, Type 1 - complications | Diabetic Cardiomyopathies - physiopathology | Time Factors | Lipids - blood | Ventricular Dysfunction, Right - physiopathology | Angiotensin I - pharmacology | Diabetes Mellitus, Experimental - complications | Ventricular Function, Right - drug effects | Diabetic Cardiomyopathies - blood | Receptors, G-Protein-Coupled - drug effects | Heart Ventricles - pathology | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - drug effects | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Cells, Cultured | Ventricular Dysfunction, Right - prevention & control | Collagen - metabolism | Animals | Receptor, Angiotensin, Type 2 - metabolism | Heart Ventricles - physiopathology | Signal Transduction - drug effects | Ventricular Dysfunction, Right - etiology | Fibrosis | Diabetic Cardiomyopathies - pathology | Heart Ventricles - metabolism | Oxidative Stress - drug effects | Blood Glucose - metabolism | Ventricular Remodeling - drug effects | Ventricular Dysfunction, Right - pathology | Heart Ventricles - drug effects | Complications and side effects | Care and treatment | Abnormalities | Angiotensin | Diabetes | Properties | Heart ventricle, Right
Journal Article
Circulation, ISSN 0009-7322, 05/2004, Volume 109, Issue 19, pp. 2296 - 2301
Journal Article
Kidney International, ISSN 0085-2538, 04/2017, Volume 91, Issue 4, pp. 818 - 829
Journal Article
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 04/2008, Volume 294, Issue 4, pp. 1220 - 1226
The purpose of this review is to examine sex differences in response to stimulation and inhibition of the renin-angiotensin system (RAS). The RAS plays a... 
Angiotensin-converting enzyme inhibitors | Janus kinase/signal transducers and activators of transcription | Angiotensin receptor blocker | Nuclear factor-κβ | Transforming growth factor-β | COLLAGEN GENE-TRANSCRIPTION | angiotensin-converting enzyme inhibitors | PHYSIOLOGY | TGF-BETA | SPONTANEOUSLY HYPERTENSIVE-RATS | nuclear factor-kappa B | janus kinase/signal transducers and activators of transcription | angiotensin receptor blocker | transforming growth factor-beta | GROWTH-FACTOR-BETA | II-INDUCED HYPERTENSION | ENZYME-RELATED CARBOXYPEPTIDASE | NITRIC-OXIDE | GENDER-DIFFERENCES | SMOOTH-MUSCLE CELLS | CONVERTING-ENZYME | Kidney Diseases - physiopathology | Estradiol - metabolism | Angiotensin II - metabolism | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Kidney Diseases - drug therapy | Receptor, Angiotensin, Type 2 - drug effects | Male | Treatment Outcome | Angiotensin II Type 1 Receptor Blockers - pharmacology | Kidney - metabolism | Receptor, Angiotensin, Type 2 - metabolism | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Signal Transduction - drug effects | Receptor, Angiotensin, Type 1 - metabolism | Sex Factors | Female | Renin-Angiotensin System - drug effects | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Receptor, Angiotensin, Type 1 - drug effects | Chronic Disease | Kidney Diseases - metabolism
Journal Article
Hypertension, ISSN 0194-911X, 09/2012, Volume 60, Issue 3, pp. 722 - 729
Angiotensin II type 2 (AT2) receptor stimulation has been linked to vasodilation. Yet, AT2 receptor-independent hypertension and hypotension (or no effect on... 
coronary circulation | mouse | compound 21 | receptor | rat | vasorelaxation | angiotensin II | Langendorff model | METABOLITES | STIMULATION | RELAXATION | AT receptor | MEDIATED VASODILATION | CORONARY VASCULAR BED | NATRIURESIS | AT RECEPTORS | NONPEPTIDE AGONIST | PERIPHERAL VASCULAR DISEASE | VASOCONSTRICTION | Mesenteric Arteries - physiology | Tetrazoles - pharmacology | Iliac Artery - drug effects | Rats, Wistar | Calcium - metabolism | Humans | Middle Aged | Receptor, Angiotensin, Type 2 - physiology | Receptor, Angiotensin, Type 2 - drug effects | Endothelium, Vascular - drug effects | Male | Mesenteric Arteries - drug effects | Angiotensin II Type 2 Receptor Blockers - pharmacology | Endothelium, Vascular - physiology | Phenylephrine - pharmacology | Biphenyl Compounds - pharmacology | Adult | Calcium Ionophores - pharmacology | Female | Models, Animal | Vasodilation - physiology | Rats, Inbred SHR | Vasoconstrictor Agents - pharmacology | Receptor, Angiotensin, Type 2 - genetics | Coronary Vessels - drug effects | Coronary Vessels - physiology | Mice, Inbred C57BL | Rats | Thiophenes - pharmacology | Imidazoles - pharmacology | Sulfonamides - pharmacology | Iliac Artery - physiology | Mice, Knockout | Animals | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Mice | Pyridines - pharmacology | Vasodilation - drug effects | In Vitro Techniques
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2013, Volume 699, Issue 1-3, pp. 160 - 171
There is increasing evidence that angiotensin II (Ang II), through binding to the type 2 (AT ) receptor may have beneficial effects in various physiological... 
AT2 receptor antagonist | MAPK activation | Angiotensin II | Neurite outgrowth | AT2 receptor agonist | receptor antagonist | receptor agonist | STIMULATION | PROTEIN-KINASE | INVOLVEMENT | AT receptor antagonist | RATS | NEURONAL DIFFERENTIATION | BLOOD-PRESSURE | AT2-RECEPTOR | AT receptor agonist | PHARMACOLOGY & PHARMACY | PC12W CELLS | CEREBRAL-ISCHEMIA | AGONIST | Angiotensin II - administration & dosage | Humans | Receptor, Angiotensin, Type 2 - drug effects | Carbamates - administration & dosage | Thiophenes - administration & dosage | Angiotensin II Type 2 Receptor Blockers - pharmacology | Dose-Response Relationship, Drug | HEK293 Cells | Indoles - pharmacology | Thiazolidinediones - pharmacology | Neurites - drug effects | Carbamates - pharmacology | Receptor, Angiotensin, Type 2 - agonists | rap1 GTP-Binding Proteins - metabolism | Angiotensin II - metabolism | Rats | Thiophenes - pharmacology | Imidazoles - pharmacology | Neurites - metabolism | Sulfonamides - pharmacology | Animals | Receptor, Angiotensin, Type 2 - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Line, Tumor | Angiotensin II Type 2 Receptor Blockers - administration & dosage | Ligands | Mice | Pyridines - pharmacology | Sulfonamides - administration & dosage | Mitogen-Activated Protein Kinase 1 - metabolism | Physiological aspects | Universities and colleges | Comparative analysis | Angiotensin
Journal Article
Free Radical Research, ISSN 1071-5762, 05/2011, Volume 45, Issue 5, pp. 575 - 584
Abstract The beneficial effects of telmisartan on Angiotensin (Ang)-II mediated oxidative stress and renal fibrosis in streptozotocin (STZ)-induced diabetic... 
Renin-angiotensin-aldosterone system | fibrosis | telmisartan | diabetic nephropathy | oxidative stress | Kidney - pathology | Receptors, G-Protein-Coupled - metabolism | Intracellular Signaling Peptides and Proteins - drug effects | Transforming Growth Factor beta1 - metabolism | Collagen Type III - metabolism | NADPH Oxidases - metabolism | Diabetic Nephropathies - drug therapy | Receptor, Angiotensin, Type 2 - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | Peptidyl-Dipeptidase A - drug effects | Angiotensin II Type 1 Receptor Blockers - pharmacology | Kidney - metabolism | NADPH Oxidases - drug effects | Diabetes Mellitus, Experimental | Peptidyl-Dipeptidase A - metabolism | Superoxides - metabolism | Transforming Growth Factor beta1 - drug effects | Receptor, Angiotensin, Type 1 - drug effects | Receptors, G-Protein-Coupled - drug effects | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - drug effects | Kidney - drug effects | Angiotensin II - metabolism | Antioxidants - pharmacology | Collagen Type III - drug effects | Diabetic Nephropathies - complications | Up-Regulation - drug effects | Hypertrophy - complications | Animals | Receptor, Angiotensin, Type 2 - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Fibrosis | PPAR gamma - agonists | Protein-Serine-Threonine Kinases - drug effects | Benzoates - pharmacology | Benzimidazoles - pharmacology | Mice | Oxidative Stress - drug effects | Hypertrophy - drug therapy
Journal Article