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Hearing Research, ISSN 0378-5955, 12/2017, Volume 356, pp. 51 - 62
Cannabinoids have been suggested as a therapeutic target for a variety of brain disorders. Despite the presence of their receptors throughout the auditory... 
Salicylate | Cannabinoids | Treatment | Tinnitus | Auditory cortex | Chronic recording | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | BRAIN-STEM | MODEL | NEUROSCIENCES | INDUCED HEARING-LOSS | RECEPTOR 1 | COCHLEAR | AUDITORY-CORTEX | OTORHINOLARYNGOLOGY | NEURAL ACTIVITY | NEURONS | RAT-BRAIN | ACOUSTIC TRAUMA
Journal Article
ChemMedChem, ISSN 1860-7179, 03/2012, Volume 7, Issue 3, pp. 452 - 463
The unwanted psychoactive effects of cannabinoid receptor agonists have limited their development as medicines. These CB1‐mediated side effects are due to the... 
peripheral | cannabinoids | agonists | receptors | protein models | CHEMISTRY, MEDICINAL | LIGAND-BINDING | ENDOCANNABINOID SYSTEM | ANALGESIC ACTIVITY | PHARMACOLOGY | RECEPTOR LIGANDS | MOUSE VAS-DEFERENS | LYSINE RESIDUE | LIGHTLY ANESTHETIZED RATS | PHARMACOLOGY & PHARMACY | ABDOMINAL CONSTRICTION RESPONSE | CRANIOFACIAL MUSCLE PAIN | Pyrazoles - therapeutic use | Benzopyrans - therapeutic use | Receptor, Cannabinoid, CB2 - agonists | Pyrazoles - chemical synthesis | Humans | Male | Pain - metabolism | Peripheral Nerves - drug effects | Peripheral Nervous System Agents - administration & dosage | Benzopyrans - chemical synthesis | Receptor, Cannabinoid, CB1 - agonists | Analgesics - chemical synthesis | Pain - drug therapy | HEK293 Cells | Peripheral Nerves - metabolism | Cannabinoids - metabolism | Binding, Competitive | Analgesics - therapeutic use | Injections, Intraperitoneal | Analgesics - administration & dosage | Models, Molecular | Rats | Blood-Brain Barrier - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Benzopyrans - administration & dosage | Pyrazoles - administration & dosage | Animals | Peripheral Nervous System Agents - chemical synthesis | Peripheral Nervous System Agents - therapeutic use | Mice | Pain Measurement | Nervous system | agonist | protein model | receptor | cannabinoid
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2011, Volume 659, Issue 2-3, pp. 139 - 145
'Spice' is an herbal blend that has been reported to produce cannabis-like effects when smoked and is marketed as an alternative to marijuana. Synthetic... 
Spice | receptor | JWH073 | Cannabinoid | CP47,497-C8 | JWH018 | DESENSITIZATION | CANNABIMIMETIC INDOLES | CLASSIFICATION | OPIOID TOLERANCE | HIPPOCAMPAL-NEURONS | INTERNALIZATION | TRANSMISSION | CB1 receptor | PHARMACOLOGY | DELTA-TETRAHYDROCANNABINOL | PHARMACOLOGY & PHARMACY | BINDING | cannabinoid
Journal Article
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 12/2012, Volume 367, Issue 1607, pp. 3353 - 3363
Human tissues express cannabinoid CB₁ and CB₂ receptors that can be activated by endogenously released 'endocannabinoids' or exogenously administered compounds... 
Receptors | Cannabinoids | Animal models | Pain | Medical treatment | Agonists | Morphine | Drug design | Endocannabinoids | Cannabinoid receptors | And CB2 | Blood-brain barrier | Cannabinoid receptor agonists | Δ9-tetrahydrocannabinol | Cannabinoid CB1 | Therapeutic applications and strategies | blood-brain barrier | Delta-tetrahydrocannabinol | cannabinoid CB1 and CB2 receptors | CB2 RECEPTOR | LIVER-DISEASES | AMYOTROPHIC-LATERAL-SCLEROSIS | ANXIETY-LIKE BEHAVIOR | MU-OPIOID RECEPTOR | RAT FORMALIN TEST | therapeutic applications and strategies | cannabinoid receptor agonists | NEUROPATHIC PAIN | MOUSE MODEL | BIOLOGY | PENTYLENETETRAZOLE-INDUCED SEIZURE | CENTRAL-NERVOUS-SYSTEM | Endocannabinoids - metabolism | Analgesics - pharmacology | Receptor, Cannabinoid, CB2 - agonists | Cardiovascular Diseases - drug therapy | Humans | Cannabinoid Receptor Agonists - pharmacology | Neurodegenerative Diseases - drug therapy | Pain - metabolism | Receptor, Cannabinoid, CB1 - agonists | Pain - drug therapy | Cannabinoid Receptor Agonists - therapeutic use | Dronabinol - pharmacology | Analgesics - therapeutic use | Cardiovascular Diseases - metabolism | Risk Assessment | Analgesics - administration & dosage | Clinical Trials as Topic | Neurodegenerative Diseases - metabolism | Blood-Brain Barrier - drug effects | Cannabinoid Receptor Agonists - administration & dosage | Drug Discovery | Blood-Brain Barrier - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Dronabinol - therapeutic use | Review
Journal Article
Journal Article
Journal Article
Journal Article
Neuroscience, ISSN 0306-4522, 2011, Volume 172, pp. 139 - 152
Abstract The cerebellum, which controls coordinated and rapid movements, is a potential target for the deleterious effects of drugs of abuse including cannabis... 
Neurology | intrinsic excitability | Purkinje neurone | cannabinoids | prenatal exposure | whole cell patch | cerebellum | Cerebellum | Intrinsic excitability | Cannabinoids | Prenatal exposure | Whole cell patch | RECEPTOR AGONISTS | SYNAPTIC-TRANSMISSION | CELL DYSFUNCTION | A-TYPE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | PYRAMIDAL NEURONS | CALCIUM CURRENTS | K+ CHANNELS | POLYCHLORINATED-BIPHENYLS | Motor Activity - physiology | Motor Skills - drug effects | Synaptic Transmission - physiology | Dyskinesia, Drug-Induced - physiopathology | Rats, Wistar | Cerebellum - drug effects | Motor Activity - drug effects | Cannabinoid Receptor Modulators - toxicity | Male | Cell Membrane - physiology | Cerebellum - abnormalities | Purkinje Cells - physiology | Receptor, Cannabinoid, CB1 - physiology | Receptor, Cannabinoid, CB1 - agonists | Time Factors | Behavior, Animal - drug effects | Female | Synaptic Transmission - drug effects | Purkinje Cells - drug effects | Benzoxazines - toxicity | Cell Membrane - drug effects | Organ Culture Techniques | Disease Models, Animal | Motor Skills - physiology | Rats | Behavior, Animal - physiology | Cerebellum - physiopathology | Prenatal Exposure Delayed Effects - physiopathology | Pregnancy | Calcium Channel Blockers - toxicity | Animals | Morpholines - toxicity | Naphthalenes - toxicity
Journal Article